Navigation Links
Nektar Announces Start of Enrollment in Phase 2 Study of NKTR-181, a Novel Opioid Analgesic Molecule, for Treatment of Chronic Pain
Date:7/24/2012

udy include quality-of-life assessment, sleep and motor activity scoring, as well as tolerability endpoints. 

The company is also planning a separate human abuse liability study for NKTR-181 as part of Phase 2 development for the compound. This study will measure liking scores for NKTR-181 as compared to an active opioid in approximately 20 recreational drug users.

About Opioids and Pain Management
Pain is one of the most common reasons people seek medical treatment.1 The American Pain Society estimates that 35.5 percent of the U.S. population, or 105 million people, suffer from chronic pain in the United States. Chronic pain conditions, such as osteoarthritis, back pain and cancer pain, affect at least 126 million adults in the U.S. annually and contribute to over $100 billion a year in direct healthcare expenditures and lost work time.1 Opioids are considered the most effective therapeutic option for pain, with sales exceeding over $10 billion a year in the U.S. alone.2,3 However, opioids can cause serious side effects such as respiratory depression and sedation and have the potential for addiction, abuse and misuse. In 2010, the Centers for Disease Control and Prevention reported that emergency room visits for non-medical use of opioid analgesics increased 111 percent over a five-year period.4

About Nektar
Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms.  Nektar has a robust R&D pipeline of potentially high-value therapeutics in oncology, pain and other therapeutic areas. In the area of pain, Nektar has an exclusive worldwide license agreement with AstraZeneca for naloxegol (NKTR-118), an investigational drug candidate, which is being evaluated in Phase 3 clinical studies as a once-daily, oral tablet for the treatment of opioid-induced constipation.  This agr
'/>"/>

SOURCE Nektar Therapeutics
Copyright©2012 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Nektar to Announce Financial Results for the First Quarter of 2012 on Wednesday, May 2, 2012, After Close of U.S.-Based Financial Markets
2. Nektar Therapeutics Reports Financial Results for the First Quarter of 2012
3. Nektar Therapeutics President and CEO Howard W. Robin to Present at the Jefferies 2012 Global Healthcare Conference in New York
4. Nektar Announces that FDA Grants Fast Track Designation to NKTR-181, a New Oral Opioid Analgesic Molecule, for the Treatment of Moderate to Severe Chronic Pain
5. Precision Optics Corporation Announces $1 Million Order for Microprecision™ Based Endoscopes
6. Young Innovations, Inc. Announces Record Sales and EPS for the Quarter Ended March 31, 2012
7. JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies
8. Misonix Announces New Distribution Agreement For Panama
9. University of Maryland BioPark Announces MedImmunes Dr. Bahija Jallal as Newest Member of Board of Directors for UM Health Sciences Research Park
10. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
11. Boston Scientific Announces CE Mark and European Launch of Emerge™ PTCA Dilatation Catheter
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... OAKS, Calif. , May 23, 2013 Amgen ... Bank 38 th Annual  Healthcare Conference on Thursday, May ... Boston , beginning at 9:20 a.m. Eastern Daylight Time. ... Relations at Amgen, will present at the conference. Live audio ... on Amgen,s website, www.amgen.com , under Investors. A replay ...
(Date:5/23/2013)... -- A recently published clinical study conducted at TOPS Comprehensive ... demonstrates that 3D mammography (breast tomosynthesis) significantly reduces unnecessary ... The study, "Implementation of Breast Tomosynthesis in a Routine ... Stephen L. Rose , MD, and published ... of Roentgenology (AJR). The AJR is the scientific ...
(Date:5/23/2013)... Anthem Blue Cross patients with HIV/AIDS may ... to obtain their medications by mail order under a ... LLC.  The lawsuit, filed in January ... mandatory mail order program announced late last year illegally ... "This settlement brings to a close a nerve-racking ...
Breaking Medicine Technology:First Large-Scale U.S. Study Validates the Benefits of 3D Mammography (Breast Tomosynthesis) Exams 2First Large-Scale U.S. Study Validates the Benefits of 3D Mammography (Breast Tomosynthesis) Exams 3Blue Cross To Allow HIV/AIDS Patients to "Opt-Out" of Mandatory Mail-Order Rx Drug Program, Announces Consumer Watchdog 2Blue Cross To Allow HIV/AIDS Patients to "Opt-Out" of Mandatory Mail-Order Rx Drug Program, Announces Consumer Watchdog 3
... George Products Company, Inc. has announced the addition ... OASIS Inspection Systems. Florida Metrology, based ... OASIS Inspection Systems is a line of highly accurate ... control departments across the United States. Tim Row of ...
... Sutro Biopharma, a biopharmaceutical company developing both ... properties, today announced that it has appointed Trevor ... Hallam will lead Sutro,s ongoing efforts in the ... platform for the research and development of novel ...
Cached Medicine Technology:Florida Metrology To Distribute OASIS Inspection Systems 2Sutro Biopharma Appoints Trevor Hallam, Ph.D., as Chief Scientific Officer 2
(Date:5/24/2013)... Routinely measuring fractional flow reserve (FFR) using pressure ... chest pain leads to significant changes in the ... results from a study reported at EuroPCR 2013. ... influence management strategy at coronary angiography for diagnosis ... whether routine assessment of FFR in all the ...
(Date:5/24/2013)... 2013 In a coup that surely made ... of the Estetica Institute of the Palm Beaches performed ... FM’s popular morning show, “The Mo & Sally Morning Show.” ... their satisfaction with the results, giving Dr. DeLange and the ... Palm Beach Gardens, very valuable free publicity. , Dr. DeLange, ...
(Date:5/24/2013)... Electric™ Energy Straws, an exciting new brand of on-the-go energy ... be the lead sponsor on Munoz’s Chevy #26 car at ... who is part of Andretti Autosports’ fantastic five racing team, ... to be named the 2013 Indy 500 Fastest Rookie Driver ... , While Munoz is grabbing headlines around the racing world ...
(Date:5/24/2013)... General Data Company Inc., a ... and data management products and solutions, has announced ... (TBS) of Durham, North Carolina, a leading manufacturer ... the clinical and research pathology marketplace. TBS will ... provides specialty products and solutions to hospitals, independent ...
(Date:5/24/2013)... presented today shows that formation of new neurons in ... importance in learning and remembering - could cause forgetting ... brain circuits. Drs. Paul Frankland and Sheena Josselyn, ... argue this reorganization could have the positive effect of ... for new learning. These results were presented at ...
Breaking Medicine News(10 mins):Health News:Diagnostic coronary angiography: Functional flow reserve changes decisions in 25 percent of cases 2Health News:Dr. Greg DeLange of the Estetica Institute Recently Performed Eye Surgery on Both Members of Popular Morning Radio Team 2Health News:Unistraw Electric™ Energy Straw Chevy Car Powers Indianapolis 500 Rookie Driver Carlos Munoz 2Health News:Unistraw Electric™ Energy Straw Chevy Car Powers Indianapolis 500 Rookie Driver Carlos Munoz 3Health News:General Data Acquires Triangle Biomedical Sciences 2Health News:General Data Acquires Triangle Biomedical Sciences 3Health News:New neuron formation could increase capacity for new learning, at the expense of old memories 2
... The International Association for Dental Research (IADR) announces Dr. ... Diseases (NIAID) at the National Institutes of Health in ... Dr. Fauci will be recognized at the 87th General ... 1, 2009. , In 1984, Dr. Fauci became director ...
... -- Thirty-seven scientists from Cold Spring Harbor Laboratory (CSHL) and ... have issued a major challenge to the neuroscience community. ... a just-published paper, to assemble a comprehensive map of the ... age in which the genomes of many organisms, including that ...
... Ga. A failing heart makes a lot of a ... the body but not enough of the enzyme needed to ... developed, Medical College of Georgia researchers found people in heart ... pro-ANP, or pro-atrial natriuretic peptide, a hormone made by heart ...
... Special Calling: Knowledge ... Leadership ... A Commitment to Caring ... With a majority of its nurses nearing retirement age, the ... members to respond to a new calling this April - ... and Continence Nurses Week, April 12 - 18, the Society ...
... SAN FRANCISCO, March 31 Pacific Fertility Center is ... preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS). ... and PGS. The use of this science for such ... for which it is used today. Pacific Fertility Center ...
... The not-for-profit LENA Foundation is putting ... of the Society of Research in Child Development (SRCD). ... talks and one poster will be presented based on ... )"This year,s SRCD is a great opportunity for our ...
Cached Medicine News:Health News:CSHL neuroscientists propose project to comprehensively map mammalian brain circuits 2Health News:CSHL neuroscientists propose project to comprehensively map mammalian brain circuits 3Health News:CSHL neuroscientists propose project to comprehensively map mammalian brain circuits 4Health News:CSHL neuroscientists propose project to comprehensively map mammalian brain circuits 5Health News:New tests provide new insight into why patients are in heart failure 2Health News:New tests provide new insight into why patients are in heart failure 3Health News:Wound, Ostomy & Continence Nurses Society Focuses On Preparing the Next Generation of Leaders 2Health News:Wound, Ostomy & Continence Nurses Society Focuses On Preparing the Next Generation of Leaders 3Health News:PGD Technology Offers More Than Designer Babies 2Health News:PGD Technology Offers More Than Designer Babies 3Health News:PGD Technology Offers More Than Designer Babies 4Health News:Five Research Studies at International SRCD Meeting in Denver Use Technology from Boulder Foundation 2Health News:Five Research Studies at International SRCD Meeting in Denver Use Technology from Boulder Foundation 3
... Stand Magnifier offers versatility across a ... lens and the light are adjustable. ... hand held objects can be worked ... parallel to the work surface, lay ...
Bausch & Lomb magnifiers incorporates precision optics and patented ergonomic designs for increased clarity and comfort during use....
... Central platform with integrated neck. Piston ... an internal spring to recoil to ready ... precision milled cavity in platform. Accepts disposable ... Designed for the use in in the ...
... TLS Surgical Markers allows ... incision sites with a scrub-resistant, ... Surgical Markers are provided sterile, ... individually packaged in peel pouches. ...
Medicine Products: