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National University Hospital Singapore Receives DSRB Approval to Use TIGR® Matrix Surgical Mesh in a New Randomized Controlled TRAM Flap Study
Date:9/13/2010

SINGAPORE, Sept. 13 /PRNewswire/ -- Novus Scientific Pte. Ltd today announced that the National University Hospital (NUH), Singapore has received Domain Specific Review Board (DSRB i.e. IRB equivalent) provisional approval for a new study: Abdominal Wall Closure After Lipectomy, TRAM/DIEP Flap - Comparison of TIGR (100% Resorbable) vs Polypropylene (Permanent) Mesh.

This is a randomized study, involving 86 patients. There are plans to expand this to a multi-site and possibly multi-centre study involving other hospitals in Singapore and in the U.S. TIGR® Matrix is the World's 1st Long-Term Resorbable Synthetic Mesh, which was launched for sale in the U.S. in June 2010. In February 2010, the US Food and Drug Administration (FDA) cleared, TIGR® Matrix Surgical Mesh for use in reinforcement of soft tissues where weakness exists.

"TIGR® Matrix is potentially an ideal prosthesis for patients undergoing breast reconstruction via TRAM Flap, as only a temporary donor site reinforcement is needed. Unlike permanent meshes, TIGR® Matrix is a long-term, synthetic, resorbable product that can be used as prophylaxis against hernia formation, while reducing the potential risk of permanent mesh related complications," said Associate Professor Thiam Chye Lim, Principal Investigator & Head of Division of Plastic, Reconstructive and Aesthetic Surgery, National University Hospital, Singapore.

TIGR® Matrix is knitted from two different resorbable fibers that degrade at different rates following implantation. This unique patented dual-fibre design provides an initial high strength / high stability configuration, with gradually increasing compliance over time as the product is degraded and resorbed. The macroporous structure is designed to permit tissue integration for tissue repair.

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