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National Jewish Health, the Nation's Premier Respiratory Hospital, Announces Lung Cancer Screening Trial Using Blood Test and CT
Date:5/1/2012

.  Approximately 85% of patients with lung cancer remain undiagnosed until the disease is symptomatic and has reached an advanced stage. Early detection of lung cancer and diagnosis improves prognosis – the current 5-year survival rate is approximately 60% for stage I lung cancer but is only 1% for those with stage IV disease. The potential of early detection of lung cancer to improve outcomes has for the first time been shown to benefit from a screening program with CT, NLST, on over 53,000 high risk smokers and ex-smokers showed a 20% mortality benefit for screening with CT compared to chest X-ray. This confirmed previous screening study reports which showed an increase in early stage and longer survival in populations which had been screened for lung cancer (2-4).  Lung cancer five-year survival rates in the US have remained at approximately 16% for decades. However, CT screening is expensive and initial calculations from the trial show it will be difficult to achieve a cost-effective position to justify broad screening use. Another concern with CT is the large number of false positive results which are produced. It is therefore very important to find a test that can further enhance the performance of CT.

About EarlyCDT-Lung

EarlyCDT-Lung – is a simple blood test that detects cancer at its earliest stages of development. EarlyCDT-Lung has been available in the US for more than two years and has been shown to detect early and late stage cancers in research studies as well as in clinical use. An audit of more than 1,600 patients, confirms the test performs in the clinical setting as expected. Oncimmune's EarlyCDT-Lung test uses a panel of tumor antigens to detect the presence of immuno-biomarkers (autoantibodies) produced by the patient's immune system when lung cancer is present. Elevation of any one of the panel of immuno-biomarkers (autoantibodies) above a predetermined cut-off value su
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SOURCE Oncimmune
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