Navigation Links
NanoBio Demonstrates New Topical Approach to Treating Nail Fungus That Circumvents Problems with Current Therapy
Date:10/27/2008

Data presented at annual ICAAC/IDSA meeting in Washington, D.C.

WASHINGTON, Oct. 27 /PRNewswire/ -- A novel topical therapy for nail fungus, NB-002, has demonstrated a new topical approach to healing nail fungus by penetrating skin pores and diffusing through the skin that surrounds the entire nail plate, according to a study conducted by NanoBio Corporation.

The data represent a unique approach to treating nail fungus (onychomycosis), which resists topical therapies because they cannot penetrate the nail and access the site of infection. The results were reported this morning at the 48th annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)/Infectious Diseases Society of America (IDSA) 46th annual meeting in Washington, D.C.

"In testing NB-002 on human cadaver skin, we have demonstrated that the lotion permeates and then laterally diffuses across tissue plains in the epidermis and the dermis to more than 1 centimeter away from the site of application," said Susan Ciotti, Ph.D., director of formulations and research and development, and presenting author of the data.

"The average great toenail measures 22 millimeters across, so we are able to deliver NB-002 across the entire span of an infected human large toenail, a huge advance in the treatment of onychomycosis," Ciotti said.

Because of its novel mode of penetration and diffusion, NB-002 is able to achieve 50 times the minimum drug concentration required to kill the fungus in the very center of the nail bed. Only 4 micrograms per gram of tissue are required for NB-002 to kill fungal infections.

Newer, more effective therapies for nail fungus are important because onychomycosis remains a large unmet medical need, according to the NanoBio scientists. Oral systemic medications are plagued by serious hepatic and cardiac toxicity concerns, while current topical medications are not effective because they are unable to penetrate to the site of i
'/>"/>

SOURCE NanoBio Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. NanoBio Corporation Completes Interim Analysis of Phase 2 Clinical Trial in Onychomycosis
2. NanoBio Corporation Successfully Completes Phase 2b Study in Herpes Labialis
3. NanoBio(R) Corporation Completes $30 Million in Equity Funding by Meeting Key Development Milestones
4. NanoBio Corporation Presents Preclinical and Interim Clinical Data on Topical Treatments for Herpes Labialis and Onychomycosis at AAD 2008
5. Landmark Study Demonstrates Potential of Radioimmunotherapy for Treatment of Indolent B-Cell Non-Hodgkins Lymphoma
6. HORIZONS AMI Trial Demonstrates Superior Outcomes with TAXUS(R) Drug-Eluting Stents in Heart Attack Patients
7. Video: Large, Multi-Center Trial Demonstrates Comparable Accuracy for Virtual Colonoscopy and Standard Colonoscopy
8. MultiVu Video Feed: Major Trial Demonstrates Comparable Accuracy of Virtual Colonoscopy and Standard Colonoscopy
9. Study Demonstrates That AHCC(R) Provides Immune Enhancement Against the West Nile Virus
10. 338 Patient Pivotal Trial Demonstrates Safety and Effectiveness of Polidocanol Sclerotherapy Product for Varicose Vein Treatment
11. Biosensors DES Demonstrates Equivalent Safety and Efficacy to Industry Leading DES in First Real World, All Comers Clinical Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... --  Memorial Hermann Health System and The University ... new partnership to provide a new level of specialized breast ... the greater Houston area. ... provider of professional breast radiology services for five of Memorial ... The Woodlands , Northeast, Southwest and ...
(Date:8/21/2014)... 2014  Publicis Groupe customer engagement agency ... and Healthcare Industry Group Leader, has been featured in ... most inspiring people in the life-sciences industry. Those chosen ... development, marketing, technology, creativity, strategy and medicine. ... partner in its leading Rosetta Consulting practice. In 2012, ...
(Date:8/21/2014)... HAMBURG, Germany , Aug. 21, 2014 /PRNewswire/ ... collaborating with Deutsches Elektronen-Synchrotron ( DESY ), a leading ... to speed up management and storage of massive volumes ... Analytics architecture based on IBM software defined technology ... data at peak performance and help scientists worldwide gain ...
Breaking Medicine Technology:Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 2Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 3Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 4Shannon Hartley Shines in PharmaVOICE 100 2DESY and IBM Develop Big Data Architecture for Science 2DESY and IBM Develop Big Data Architecture for Science 3
(Date:8/21/2014)... 21, 2014 The City of Garden ... entertainment and programming for its inaugural “Re:Imagine Garden Grove ... 12, 2014, from 11 a.m. to 4 p.m., 2.85-miles ... cars and the downtown will be filled with diverse ... Community Arts Resources (CARS), for all to enjoy. , ...
(Date:8/21/2014)... Aug. 21, 2014 (HealthDay News) -- Among seniors, dimming ... The study involved more than 2,500 people, aged 65 ... study and again two, six and eight years later. ... the person,s risk of death during the study period, the ... effect, researchers led by Sharon Christ of Purdue University in ...
(Date:8/21/2014)... 21, 2014 A new study published ... increase in disability associated with speech problems from 2001-02 ... than 15% increase in disability associated with hearing problems. ... rising numbers of children who are experiencing communication disorders, ... , On a broader level, the new study, ...
(Date:8/21/2014)... Aug. 21, 2014 Researchers in the United Kingdom ... can quickly and accurately diagnose a number of rare ... study published online today in Ophthalmology , ... Using a single test, doctors were able to tailor ... mutations reducing the time and money spent on diagnosis ...
(Date:8/21/2014)... The report "Industrial Flue Gas Treatment Systems & ... Particulate Control, Mercury Control) by Application (Power Generation, ... Global Trends & Forecasts to 2019" defines and ... & services market with analysis and projection of ... The industrial flue gas treatment systems & services ...
Breaking Medicine News(10 mins):Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 2Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 3Health News:"Re:Imagine Garden Grove - A Downtown Open Streets Event" 4Health News:Failing Vision Tied to Shorter Lifespans for Seniors 2Health News:New Pediatrics Study Reveals Dramatic Increase in Speech Problems in Children Over Past Decade 2Health News:New Pediatrics Study Reveals Dramatic Increase in Speech Problems in Children Over Past Decade 3Health News:New DNA test for diagnosing diseases linked to childhood blindness 2Health News:Industrial Flue Gas Treatment Systems Market Estimated to Worth $59, 546.7 Million by 2019 – Report by MarketsandMarkets 2Health News:Industrial Flue Gas Treatment Systems Market Estimated to Worth $59, 546.7 Million by 2019 – Report by MarketsandMarkets 3Health News:Industrial Flue Gas Treatment Systems Market Estimated to Worth $59, 546.7 Million by 2019 – Report by MarketsandMarkets 4
... have felt elated using the tanning beds and cannot seem ... the elation than just the look good factor of the ... , have researched the background of the ‘feel good’ ... tan could also be igniting euphoric sensations, akin to the ...
... Jerry Mendell a neurologist, co-director of the Muscular ... professor of pediatrics, neurology and pathology at Ohio ... the Neuromuscular Research Program and Gene Therapy Center ... injection of Asklepios Biopharmaceutical Inc (AskBio’s) Biostrophin, which ...
... 570,000 children under the age of 15 die of AIDS ... - states a new global report highlighting concerns about the ... the World Health Organization (WHO) and the Joint United Nations ... HIV ART in low- and middle- income countries more than ...
... Rayburn, a cardiologist from the University of Alabama, Birmingham, told ... the drug showed no significant difference in the rate of ... or placebos. The drug Vioxx is produced and marketed by ... told a jury that the studies, covering a total of ...
... At fairing well in examining the heart and making ... They fair better than medical students, residents, and other ... in accurately identifying abnormal heart sounds. This was revealed ... Archives of Internal Medicine. ,The study was performed ...
... A new study has found that smoking and drinking at ... has exposed the adverse effects of tobacco and alcohol has ... second leading cause of cancer deaths, and doctors generally recommend ... Typically, the disease is diagnosed in people in their late ...
Cached Medicine News:Health News:Wider Addictive Choices – Now, Tanned Addicts 2Health News:Trial Of DMD Gene Therapy Initiated At Ohio 2Health News:AIDS Deaths On The Rise Due To Low Access To Antiretroviral Treatment 2Health News:Could Long Tern Vioxx Users Suffer From Heart Attacks? 2