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NanoBio Corporation Completes Interim Analysis of Phase 2 Clinical Trial in Onychomycosis
Date:3/20/2008

iac toxicity, as well as the potential for drug interactions," Baker added.

NB-002 has documented fungicidal activity against numerous fungi involved in cutaneous infections, including Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis and Candida albicans.

About Onychomycosis

Onychomycosis is a chronic, persistent fungal infection of the nail bed resulting in unsightly thickening and discoloration of the nail, which sometimes can be accompanied by pain and disability. According to Podiatry Today, more than 35 million people in the United States have onychomycosis. Estimates indicate that up to 50 percent of those affected by the disease do not receive treatment.

Systemic treatments represent well over 80 percent of the market today, but they have potential toxicity issues and have shown to have relapse rates of 40 percent or higher. The only approved topical treatment for onychomycosis has demonstrated an efficacy rate ranging from 5 percent to 12 percent.

About NanoBio

NanoBio(R) Corporation is a privately held biopharmaceutical company focused on developing and commercializing anti-infective products and mucosal vaccines derived from its patented NanoStat(TM) technology platform. The company's lead product candidates are treatments for herpes labialis (cold sores), onychomycosis (nail fungus), MRSA and mucosal vaccines for influenza and hepatitis B. The company's headquarters and laboratory facilities are located in Ann Arbor, Mich.


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