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NanoBio Awarded Up To $10 Million In NIH Funding To Develop A Pandemic Influenza Vaccine
Date:10/29/2013

ANN ARBOR, Mich., Oct. 29, 2013 /PRNewswire/ -- NanoBio Corporation today announced that the company has been awarded an initial contract worth $5.5 million from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), to develop a nanoemulsion (NE) adjuvant for use with a pandemic influenza vaccine. The total contract is valued at approximately $10.5 million, if all options are exercised.

The funding from NIAID will specifically support the research and development of NanoVax®-Panflu, which combines NanoBio's proprietary NE adjuvant with a plant-based recombinant H5 pandemic influenza antigen. This adjuvanted vaccine has the potential to provide enhanced protection against infection by eliciting both mucosal and systemic immunity. Various research efforts have concluded that achieving mucosal immunity is critical for pathogens that enter the body across mucosal surfaces causing respiratory infections and sexually transmitted diseases.

"Our most recent studies at NanoBio have tested NE-adjuvanted vaccines for respiratory syncytial virus (RSV) and type 2 genital herpes (HSV2), two viruses that enter the body via mucosal sites," said David Peralta, chief executive officer of NanoBio. "The results of these studies very clearly demonstrate the ability of the NE adjuvant to elicit mucosal immunity and the important role this type of immunity plays in protecting against disease."

The award includes a future option to test the NE adjuvant with an HIV vaccine. The vaccine will combine NanoBio's NE adjuvant with recombinant HIV virus-like particles. HIV is a global epidemic; the virus is primarily transmitted through sexual contact. A vaccine that elicits mucosal immunity has the potential to minimize transmission of HIV.

Mr. Peralta added, "With this contract support from NIAID, we
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SOURCE NanoBio Corporation
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