Navigation Links
NVA237 Filed in Europe and Positive Phase III Data at European Respiratory Society Congress
Date:9/26/2011

TOKYO, September 27, 2011 /PRNewswire/ --

NVA237 has been filed for marketing authorisation by Novartis with the European Medicines Agency (EMA) under the brand-name Seebri® Breezhaler®, triggering a $5m milestone payment to Sosei

Studies show investigational once-daily NVA237 provides superior 24-hour bronchodilation and increases exercise endurance relative to placebo

Additional data show NVA237 significantly prolonged time to first moderate/ severe COPD exacerbation and reduced associated hospitalizations compared to placebo

Sosei Group Corporation ("Sosei"; TSE Mothers Index: 4565), today announces that NVA237 (glycopyrronium bromide), a long-acting muscarinic antagonist (LAMA) being investigated as a once-daily treatment for chronic obstructive pulmonary disease (COPD), has been filed by Novartis for marketing authorisation with the European Medicines Agency (EMA), under the brand-name Seebri® Breezhaler®, triggering a $5m milestone payment to Sosei.

In addition, Novartis has presented new NVA237 Phase III data at the European Respiratory Society (ERS) congress.  The GLOW1 and GLOW3 studies in chronic obstructive pulmonary disease (COPD) patients show that NVA237 (glycopyrronium bromide) significantly increased patients' lung function compared to placebo with a fast onset of action at first dose, as well as improving exercise endurance.  NVA237 is a new drug in the long-acting anti-muscarinic (LAMA) class.

The GLOW1 study met its primary endpoint by showing that NVA237 50 mcg once-daily produced a significant improvement in lung function of 108 mL in trough FEV1 (forced expiratory volume of breath in one second) after 12 weeks in patients with moderate-to-severe COPD compared to placebo (p<0.001). Moreover, NVA237 had a rapid onset of action, with a 93 mL improvement in FEV1 compared to placebo at five minutes post-dose fo
'/>"/>

SOURCE Sosei Group Corporation
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Phase III Study Shows Once-Daily NVA237 is Superior to Placebo and Similar to Tiotropium in Improving Lung Function in COPD
2. Sosei and Vectura Announce Start of Phase III Clinical Study With NVA237
3. NVA237 Phase II Results Presented at the European Respiratory Society Annual Meeting Show Promising Efficacy and Tolerability With Potentially Faster Onset Than Tiotropium
4. 13D Amendment Filed for RepliGen Corporation
5. Mr. Ronald L. Chez Filed Amended 13D for RepliGen Corporation
6. Recalled DePuy ASR Hip Implant Lawsuits Filed By John David Hart
7. Simcere Pharmaceutical Group Filed 2010 Annual Report on Form 20-F
8. Recalled DePuy Hip Implant Lawsuits Filed in Fort Worth, Texas
9. Shrink Nanotechnologies Announces That Critical Cell Align Tissue Engineering Platform Patent as Well as IP on a Novel Immunoassay Substrate Material Has Been Filed With the USPTO
10. Law Offices of John David Hart: DePuy Recalled Hip Device Lawsuit Filed by Houston Woman
11. DePuy Recalled Hip Device Lawsuit Filed in Austin, Texas
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... Ireland , August 22, 2014 /PRNewswire/ ... and Markets ( http://www.researchandmarkets.com/research/x34qgv/global_laboratory ) has announced the ... Market 2014-2018"  report to their offering.  ... balance is an essential instrument for any ... the precise weighing of materials. It can ...
(Date:8/22/2014)...  Diplomat, the nation,s largest independent specialty pharmacy, ... in the 2014 Innovations in Specialty Pharmacy Competition, ... of the competition were announced in the August ... Diplomat was honored as a Top Innovator ... Through Diplomat University, the company has implemented a ...
(Date:8/22/2014)... , Aug. 22, 2014 Research ... "Stem Cell Research Products: Opportunities, Tools & Technologies" ... already supply stem cell research products or you wish ... essential and lucrative this market is. The authors know ... sell more effectively to scientists, to generate improved revenues ...
Breaking Medicine Technology:Global Laboratory Electronic Balance Market 2014-2018: Key Vendors are A&D Company, Mettler-Toledo, Sartorius and Thermo Fisher 2Diplomat honored as a Top Innovator by Specialty Pharmacy News 2Global Stem Cell Research Products: Opportunities, Tools & Technologies - 2014 Report 2Global Stem Cell Research Products: Opportunities, Tools & Technologies - 2014 Report 3
... 2011 Bayer HealthCare Pharmaceuticals Inc. today ... cohort safety study offer insights into the increased risk ... a well-established risk in women who use combination oral ... Specifically, the new data provides healthcare providers with information ...
... Therapeutics today announced  the initiation of a Phase ... XMT-1001 , a novel DNA topoisomerase I inhibitor based ... in second-line gastric cancer and second-/third-line non-small cell lung ... clinical centers in the US.  The Phase 1b follows ...
Cached Medicine Technology:New Interim Data About Combination Oral Contraceptives 2New Interim Data About Combination Oral Contraceptives 3New Interim Data About Combination Oral Contraceptives 4New Interim Data About Combination Oral Contraceptives 5New Interim Data About Combination Oral Contraceptives 6Mersana Therapeutics Initiates Phase 1b Extension Study of XMT-1001 in Gastric Cancer and Non-Small Cell Lung Cancer 2Mersana Therapeutics Initiates Phase 1b Extension Study of XMT-1001 in Gastric Cancer and Non-Small Cell Lung Cancer 3
(Date:8/22/2014)... Va. (PRWEB) August 22, 2014 On ... Center for Medical and Health Sciences , hosting a ... area’s top influencers in government and public welfare. , ... College of Osteopathic Medicine (LUCOM) joined Liberty staff, ... and the launch of the new medical school. Classes ...
(Date:8/22/2014)... Las Vegas, NV (PRWEB) August 22, 2014 ... authentic content that is written by marketing experts for ... and affiliate links has caught the attention of Shane ... is involved with Internet marketing in any way knows ... or failure in the industry,” reports Michaels. “But even ...
(Date:8/22/2014)... 2014 Japantown Dental is excited to ... whitening technique. Air polishing is a technique used to ... teeth can be caused by a number of factors, ... internal stains. External stains include coffee, wine, tea, smoking ... certain medications, such as tetracycline, and direct trauma to ...
(Date:8/22/2014)... team has found that targeted automated alerts in ... in hospital patients with urinary catheters. In addition, ... the rate of improvement dramatically increased. , The ... urinary catheters in the first place and then ... that have not been removed within a recommended ...
(Date:8/22/2014)... NV (PRWEB) August 22, 2014 Natural ... Kevin Richardson to restore his own vision from legally blind ... Michaels, prompting an investigative review. , “There is a ... or contacts for everyday function, and most people just think ... to corrective eye surgery that can be pretty risky at ...
Breaking Medicine News(10 mins):Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 2Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 3Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 4Health News:My Writers: Review Exposes Online Source for Quality Marketing Content 2Health News:Japantown Dental Introduces Air Polishing 2Health News:Penn study: Electronic alerts significantly reduce catheter-associated urinary tract infections 2Health News:Penn study: Electronic alerts significantly reduce catheter-associated urinary tract infections 3Health News:Natural Clear Vision: Review Exposes Kevin Richardson’s Program for Restoring Vision Naturally 2
... Inaugural Gala, NORTH ADAMS, Mass., Nov. 14 ... today announced that it will hold,its first Roundtable meeting ... Institute, established by NPSF in May 2007, is a,think ... action for,the field of patient safety. Its goal is ...
... , Ohio -- Scientists are one step closer to ... for supporting life. , For the first time, scientists ... protein molecules to enable different functions to happen. , ... of the Proceedings of the National Academy of Sciences, ...
... your name and initials? Most people do and, as past ... other important behaviors. For example, Jack is more likely to ... is more likely to move to Philadelphia and marry Phyllis. ... it is influential enough to encourage the pursuit of name-resembling ...
... in the World Journal of Gastroenterology on November 7, ... case of gastric carcinosarcoma obtained in this part of ... Tomislav Randjelovic as surgeon and Dr. Branka Filipovic as ... his team; the anatomical and patoanatomical evaluation of macroscopic ...
... Asenapine -- a fast-,dissolving, sublingual tablet being ... and well-tolerated in patients with acute schizophrenia,according to ... of the Journal,of Clinical Psychiatry. These data were ... meeting and at the annual,congress of the European ...
... International,Isotopes Inc. (OTC Bulletin Board: INIS) is pleased ... Chief Financial Officer (CFO),effective November 13, 2007. ... 2007,as Chief Accounting Officer. Ms. McKenzie-Carter has approximately ... Previously, she served as,chief accountant for a sizeable ...
Cached Medicine News:Health News:Lucian Leape Institute Announces First Roundtable 2Health News:Lucian Leape Institute Announces First Roundtable 3Health News:Scientists get first look at how water 'lubricates' proteins 2Health News:What's in a name? Initials linked to success, study shows 2Health News:Study Shows Organon's Asenapine Demonstrates Efficacy and Tolerability in Treating Acute Schizophrenia 2Health News:Study Shows Organon's Asenapine Demonstrates Efficacy and Tolerability in Treating Acute Schizophrenia 3Health News:Study Shows Organon's Asenapine Demonstrates Efficacy and Tolerability in Treating Acute Schizophrenia 4Health News:Laurie McKenzie-Carter Named Chief Financial Officer of International Isotopes Inc. 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: