Navigation Links
NT-proBNP Guided Therapy Keeps Heart Failure Patients out of the Hospital Through a Reduction in Cardiovascular Events
Date:11/15/2010

11; a global burdenIt is estimated that as many as five million Americans have heart failure, with 400,000-500,000 new cases/year; the diagnosis carries a mortality rate that exceeds many cancers. Heart failure ranks among the most costly chronic conditions in developed countries, with the burden being greatest among the elderly. Heart failure hospitalization represents a major burden on the healthcare system both in the U.S. and the rest of the world.

Given this rapidly increasing incidence of heart failure and relative shortage of novel therapies for diagnosis, a new strategy of care utilizing existing therapies, including the intention to not only address symptoms, but also to lower NT-proBNP concentrations with the goal of reducing risk in parallel, would not only contribute to better patient outcomes, but also likely reduce healthcare costs.

About the Roche sponsored PROTECT studyPROTECT, a prospective randomized trial comparing a strategy of aggressive heart failure therapy guided by levels of a cardiac hormone—amino-terminal pro-B type natriuretic peptide (NT-proBNP)—versus standard heart failure treatment without NT-proBNP guidance has been enrolling subjects in the Heart Center at the Massachusetts General Hospital since 2006.  In December 2009 the promising results of the interim analysis supported the early closure of the study.

Besides the primary endpoint of total cardiovascular events over a one year period, other endpoints in PROTECT will include effects of NT-proBNP guidance on quality of life, effect of NT-proBNP guided care on cardiac structure and function, and overall costs of care.  Publication of the results is expected in the next few months.

About NT-proBNPTests for NT-proBNP, a cardiac hormone that is released into the blood when the heart wall is stretched, are developed and marketed by Roche. NT-proBNP was approved by the U.S. Food and Drug Administration (FDA) as an objective marker
'/>"/>

SOURCE Roche Diagnostics
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Study Reveals Potential for NT-proBNP as a Marker to Predict Cardiovascular Risks From Anti-Inflammatory Drugs
2. Image Guided Radiation Therapy in Latham, NY. Now Fighting Cancer Using Fast and Precise RapidArc(TM) Radiotherapy Technology
3. Guided Delivery Systems, Inc. Successfully Treats First Patient with Mitral Regurgitation
4. Advanced Image-Guided Surgery Technology From BrainLAB Now Available in New York State
5. Abstract Submissions and Registration Now Open for 2nd International Symposium on MR-Guided Focused Ultrasound
6. MR-Guided Focused Ultrasound Symposium Announces Sponsors
7. Western European Market for Image-guided and Robot-assisted Surgery
8. Varian Medical Systems and IMRIS to Co-Develop Revolutionary New MR-Guided Radiation Therapy System
9. Varian Medical Systems Introduces New TrueBeam™ System for Image-Guided Radiotherapy and Radiosurgery to Clinicians in Asia at AOCMP in Taipei, Taiwan
10. Celsion Announces ThermoDoxs Prominence in Abstracts Presented at the 2nd International MR-Guided Ultrasound Symposium
11. Varian Medical Systems to Exhibit TrueBeam™ System for Image-Guided Cancer Treatments and New Software Capabilities at ASTRO Meeting in San Diego
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... Calif. , July 10, 2014 Integrated ... leader in advanced memory and analog IC solutions, today ... on Thursday, July 24, 2014, at 7:00 a.m. Pacific ... financial results for the fiscal 2014 third quarter ended ... call via telephone, dial 1-888-556-4997 before 6:50 a.m. Pacific ...
(Date:7/10/2014)...  Valeant Pharmaceuticals International, Inc. (NYSE: VRX ... the sale to Galderma of all rights to Restylane, ... Valeant for $1.4 billion in cash, pursuant to the ... its acquisition of Galderma. "We are ... a company that is firmly committed to the aesthetic ...
(Date:7/10/2014)... R.I. , July 10, 2014 CVS Caremark ... board of directors has approved a quarterly dividend of $0.275 ... dividend is payable on August 1, 2014, to holders of ... CVS Caremark is dedicated to helping people ... pharmacy company in the United States . ...
Breaking Medicine Technology:
... Calif., Oct. 10 Amgen (Nasdaq:  AMGN) today ... pivotal Phase 3 trials comparing denosumab to Zometa® ... the prevention of skeletal related events (SREs) in ... separate analyses, denosumab demonstrated a clinically meaningful, consistent ...
... Oct. 8 The American Dental Association (ADA) has ... ), the largest provider of health care products and ... at $860,000 to students in the Community Dental Health ... initially for hands-on clinical training in the program, which ...
Cached Medicine Technology:Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 2Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 3Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 4Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 5Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 6Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 7Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 8Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 9Integrated Analysis Demonstrates That Denosumab Delays the Onset of Bone Complications Compared to Zometa® 10Henry Schein Inc. Donates Equipment to ADA Community Dental Health Coordinator Pilot Program 2Henry Schein Inc. Donates Equipment to ADA Community Dental Health Coordinator Pilot Program 3
(Date:7/13/2014)... TX (PRWEB) July 13, 2014 The Pearland, ... children ranging in age from four months to 12 years ... and karate classes to birthday parties and Summer Camps, is ... Little Gym of Pearland after spending over six ... of roles, including Gym Director. , Berry has over ...
(Date:7/13/2014)... Recently, MyDressCity.com, one of the most popular suppliers of ... its new range of elegant Quinceanera dresses . ... discounted prices. Worldwide clients can enjoy this special offer ... online shop, there are plenty of beautiful dresses for ... materials. MyDressCity.com’s hot items are prom gowns, bridesmaid gowns, ...
(Date:7/13/2014)... 13, 2014 According to the Kidney Disease ... step by step guide on what to do to eliminate ... quickly. Vkool writes in its review that readers can easily ... to revitalize their kidney health. Vkool also informs in its ... reverse their damaged kidney functions naturally. The book consists of ...
(Date:7/13/2014)... Hope Palliative & Hospice Care announced today that they will ... Senior Living Community in Palatine, IL. The group, called “New ... Wednesdays of every month. This group will begin on ... 55 S. Greeley St. Palatine, IL 60067. It is ... for the group. , “A grief support group is ...
(Date:7/12/2014)... 13, 2014 According to the new ... Systems, Airborne Systems, and Naval Systems) - Global Forecasts ... Security and Surveillance Radar market are estimated to be ... a CAGR of 5.97% to reach $8.61 billion by ... with 47 figures spread through 161 pages and in-depth ...
Breaking Medicine News(10 mins):Health News:The Little Gym of Pearland, TX Now Under New Ownership and Management 2Health News:Cheap Elegant Quinceanera Dresses Unveiled by MyDressCity.com 2Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 2Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 3Health News:Hope Hospice Announces Grief Support Group at the Tamarack Senior Living Community 2Health News:Security and Surveillance Radar Market Estimated to Reach $8.61 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Security and Surveillance Radar Market Estimated to Reach $8.61 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Security and Surveillance Radar Market Estimated to Reach $8.61 Billion by 2020 – New Report by MarketsandMarkets 4
... a startling find. Around 75 percent of whites or those ... of developing heart diseases. And that’s not all. These genes ... diabetes. ,The findings, made by two independent groups of ... even if they do not have clear risk factors such as ...
... American doctor has threatened to mobilise US congressmen and senators ... Information (RTI) Act in a case relating to his crusade ... Saha, whose wife died of alleged wrongful treatment in India ... my senators and congressmen in US and will ask them ...
... Human Resource Development in collaboration with National AIDS Control ... Adolescence Education Programme (AEP) which is being implemented by ... ,The Programme is aimed at the ... of the major concerns, i.e. process of growing up ...
... that can enable the blind to hear what they cannot see ... texts through an embedded system and converts them into voice that ... can only read text, but later it is likely to pick ... that took six months to develop the device and the software ...
... to detect epidemic diseases has entered the phase of clinical ... methods that rely on antigen or antibody test, the new ... DNA or RNA, to confirm epidemic diseases such as hepatitis ... Centre of US National Institutes of Health (NIH). ...
... and women who consumed higher levels of calcium and vitamin ... brain lesions, regions of damage// that can increase risk of ... Payne and her co-investigators from Duke and the University of ... men and women (79 men, 153 women) between the ages ...
Cached Medicine News:Health News:Gene Mutations Leave Caucasians Prone To Heart Diseases And Diabetes 2Health News:NRI Threatens to Move US Congress for Justice in India 2Health News:Higher Intake of Calcium and Vitamin D Linked With Brain Lesions in Older People 2
... The Asnis III™ Cannulated Screw System has ... and TCS Systems and combined them to ... screws in both titanium and stainless steel. ... System is designed to optimize surgical outcomes ...
The 6.5mm cannulated cancellous ACE SCFE Screw is specifically designed for the treatment of slipped capital femoral epiphysis. The ACE SCFE Screw simplifies insertion and facilitates removal....
... a wide variety of cannulated screw products. ... partially threaded and fully threaded versions. , ... and 7.0 mm products. These incorporate innovative ... a little easier. Ratchet screwdrivers have proven ...
Biomet® Arthrodesis Nail indications include: , Failed external fixation , Aseptic failed total knee arthroplasty , Periarticular fractures where repair is not possible , Limb salvage in tumor...
Medicine Products: