Navigation Links
NT-proBNP Guided Therapy Keeps Heart Failure Patients out of the Hospital Through a Reduction in Cardiovascular Events
Date:11/15/2010

INDIANAPOLIS, Nov. 15, 2010 /PRNewswire-FirstCall/ -- Roche (SIX: RO, ROG; OTCQX: RHHBY) and study investigators from Harvard University and Massachusetts General Hospital announced today that in the PROTECT (Pro-BNP Outpatient Tailored Chronic HF Therapy) trial, a strategy of NT-proBNP guided heart failure care was independently associated with a significant reduction in total cardiovascular events, the primary composite endpoint of the study, which included worsening heart failure, heart failure hospitalization and cardiovascular related death.

"The data of the study indicates a significant difference between the treatment arms in favor of the NT-proBNP group", the principal investigator Dr James Januzzi, associate professor of medicine at Harvard Medical School and director of the Cardiac Intensive Care Unit at the Massachusetts General Hospital, said in his talk. "We are excited to see that following the interim results, the full results of the trial support the concept of biomarker-guided heart failure care."

In the PROTECT study, patients with chronic systolic heart failure (left ventricular ejection fraction <40%) were randomized to one of two treatment approaches: a standard-of-care arm, where patients received aggressive guideline-compliant heart failure care, or an NT-proBNP arm, where patients were treated with similar aggressive clinical care, but with a simultaneous goal to decrease and maintain NT-proBNP concentrations below 1,000 pg/mL, a value which previous studies have shown the cardiovascular event risk in heart failure to be considerably lower.(1)

"While previous studies have returned mixed results with respect to the approach of "guided therapy" with natriuretic peptide testing, the reduction in total cardiovascular events in the NT-proBNP arm suggests the important role of this cardiac hormone in the management of heart failure," Dr. Januzzi said.

Heart failure R
'/>"/>

SOURCE Roche Diagnostics
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine technology :

1. Study Reveals Potential for NT-proBNP as a Marker to Predict Cardiovascular Risks From Anti-Inflammatory Drugs
2. Image Guided Radiation Therapy in Latham, NY. Now Fighting Cancer Using Fast and Precise RapidArc(TM) Radiotherapy Technology
3. Guided Delivery Systems, Inc. Successfully Treats First Patient with Mitral Regurgitation
4. Advanced Image-Guided Surgery Technology From BrainLAB Now Available in New York State
5. Abstract Submissions and Registration Now Open for 2nd International Symposium on MR-Guided Focused Ultrasound
6. MR-Guided Focused Ultrasound Symposium Announces Sponsors
7. Western European Market for Image-guided and Robot-assisted Surgery
8. Varian Medical Systems and IMRIS to Co-Develop Revolutionary New MR-Guided Radiation Therapy System
9. Varian Medical Systems Introduces New TrueBeam™ System for Image-Guided Radiotherapy and Radiosurgery to Clinicians in Asia at AOCMP in Taipei, Taiwan
10. Celsion Announces ThermoDoxs Prominence in Abstracts Presented at the 2nd International MR-Guided Ultrasound Symposium
11. Varian Medical Systems to Exhibit TrueBeam™ System for Image-Guided Cancer Treatments and New Software Capabilities at ASTRO Meeting in San Diego
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... , May 22, 2013 /PRNewswire-iReach/ -- World ... aligned with the latest trends and events, companies ... can predict where an industry is headed next, ... (Photo: http://photos.prnewswire.com/prnh/20130522/CG19099 ) ... with market research publisher GlobalData, offer decision makers ...
(Date:5/22/2013)... and MUNICH , May 22, 2013 /PRNewswire/ ... marketer of transcatheter aortic valve implantation (TAVI) systems for the ... results of the J enaValve Eval U ation of ... Pa T ients with S E vere Ao R tic ... . JUPITER is a post-market registry to evaluate five-year long ...
(Date:5/22/2013)... May 22, 2013  Milliman, Inc., a premier global ... its 2013 Milliman Medical Index (MMI), which measures the ... receiving healthcare benefits through an employer-sponsored preferred provider organization ... family in 2013 is $22,030. "For ... year on a percentage basis was the lowest in ...
Breaking Medicine Technology:Adapt, React, Evolve: Staying Ahead in the Breast Cancer Gene Testing, Solar Energy, and Oil & Gas Markets with Reliable Analytics and Actionable Insights from GlobalData's 700 Market Analysts 2Adapt, React, Evolve: Staying Ahead in the Breast Cancer Gene Testing, Solar Energy, and Oil & Gas Markets with Reliable Analytics and Actionable Insights from GlobalData's 700 Market Analysts 3Adapt, React, Evolve: Staying Ahead in the Breast Cancer Gene Testing, Solar Energy, and Oil & Gas Markets with Reliable Analytics and Actionable Insights from GlobalData's 700 Market Analysts 4First Results Of The JUPITER Registry On Long Term Performance And Safety Of The Transapical JenaValve TAVI System 2First Results Of The JUPITER Registry On Long Term Performance And Safety Of The Transapical JenaValve TAVI System 3First Results Of The JUPITER Registry On Long Term Performance And Safety Of The Transapical JenaValve TAVI System 4Annual Healthcare Cost for a Typical American Family is $22,030 According to 2013 Milliman Medical Index 2
... Liberate Cosmetic Surgery hopes to raise awareness of ... confidence within the cosmetic surgery industry through the launch of ... their on-going activity on the subject, such as question and ... launching some exciting new initiatives online, that it hopes people ...
... 2011 The U.S. Food and Drug Administration ... (olanzapine tablets) and Zyprexa Zydus (olanzapine orally disintegrating ... (Logo: http://photos.prnewswire.com/prnh/20090824/FDALOGO ) Schizophrenia ... About 1 percent of Americans have this illness. ...
Cached Medicine Technology:Liberate Cosmetic Surgery aims to Highlight Cosmetic Surgery Industry Issues 2FDA Approves First Generic Olanzapine to Treat Schizophrenia, Bipolar Disorder 2FDA Approves First Generic Olanzapine to Treat Schizophrenia, Bipolar Disorder 3
(Date:5/22/2013)... may be reaping enormous income for patients whose ... contracted in their intensive care units. , In ... American Journal of Medical Quality , the ... an avoidable central line-associated bloodstream infection (CLABSI) costs ... a similar infection-free patient. Moreover, hospitals earn nearly ...
(Date:5/22/2013)... 22, 2013 Phelps Memorial Hospital Center ... Westchester Lung Nodule Center for individuals who would like ... care. Lung cancer is the deadliest form of cancer for ... the U.S. die from lung cancer than from breast, colon ... early detection increases survival rates. It is well established ...
(Date:5/22/2013)... RI (PRWEB) May 22, 2013 Hurricane ... weatherproofing your home. That’s why Amica Insurance ... coverages for the upcoming hurricane season. , “An important ... said Bryan Cook, a senior assistant vice president at ... needs is before the threat of a storm.” , ...
(Date:5/22/2013)... Daytona Beach, FL (PRWEB) May 22, 2013 ... have signed on as a sponsor for this weekend's I ... will take place at 8:00 am at Cocoa Riverside Park ... the community through the I Talk to Strangers social movement. ... team of runners and walkers to participate in the event. ...
(Date:5/22/2013)... HR Strategies recently participated in the Gwinnett Relay ... on Friday May 10, 2013. For never having participated ... over $6,300 for cancer research. , HR Strategies ... first $3,000 for Bronze Level Sponsorship. HR Strategies CEO, ... match the company’s contribution of $3,000; and after just ...
Breaking Medicine News(10 mins):Health News:Hospitals profit when patients develop bloodstream infections 2Health News:Hospitals profit when patients develop bloodstream infections 3Health News:Hospitals profit when patients develop bloodstream infections 4Health News:Phelps Memorial Hospital Center Establishes The Westchester Lung Nodule Center To Diagnose And Administer Lung Cancer Care 2Health News:Phelps Memorial Hospital Center Establishes The Westchester Lung Nodule Center To Diagnose And Administer Lung Cancer Care 3Health News:Reviewing Insurance Policies: a Key Part of Hurricane Preparations 2Health News:Space Girl Organics to Sponsor May 25 Miracle Run/Walk 2Health News:HR Strategies Raises Over $6,300 for Cancer Research via Relay For Life 2
... government are needed to improve mental health in Australia//. ... in need of a new nationalwise approach with acute-care facilities ... on the Time for Service says mental health funding of ... years was being made. ,It added, about 13 ...
... researchers to find out about the breast cancer in younger ... ,Comparing with the white women the number of black ... contrary the mortality rate among the black women is much ... blacks under the age of 50 have a 77 percent ...
... of allied health professional converge on a platform to discuss ... Canada. ,In the words of Professor ... IOF World Congress on Osteoporosis 2006 Scientific Committee, “We are ... important congress as they form an important part of the ...
... Suspected malaria with jaundice has claimed 17 lives in ... in Tirap district of Arunachal Pradesh, district medical officer ... PTI that the preventive steps were taken on war ... on June four local legislator Wanki Lowang had claimed ...
... Asia-Pacific Economic Cooperation (APEC),launched a bird flu exercise ... emergency communication and response to a human,influenza pandemic. ... make real-time decisions,based on a hypothetical scenario in ... the first exercise in a series that will ...
... infant mortality rates, the Centre has asked the state governments ... of the initiative for polio immunisation. // ,Breast ... cent. It is not only the best food for the ... throughout life, Secretary Women and Child Development Reva Nayyar said., ...
Cached Medicine News:Health News:Breast Cancer Mortality Rate is Higher Among Black Women 2Health News:Breast Cancer Mortality Rate is Higher Among Black Women 3Health News:APEC Launches Bird Flu Exercise 2
Quantitative determination of Fibrinogen (Clauss Method). Freeze-dried human thrombin (~100NIH units/mL) with heparin inhibitor and calcium....
Determination of Prothrombin Time (PT) by STA Analyzers (ISI~1.3).Freeze-dried rabbit brain thromboplastin with heparin inhibitor....
Determination of Prothrombin Time (PT)by STA Analyzers (ISI~1.8).Freeze-dried rabbit brain thromboplastin with heparin inhibitor....
For the quantitative in vitro determination of creatinine in serum, plasma or urine....
Medicine Products: