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NSVascular, Inc., a NeuroSigma Subsidiary, Signs an Exclusive License Covering UCLA's Thin-Film Nitinol (TFN) Stent Technology for Endovascular Applications
Date:7/18/2011

tain aneurysms.  Last month, in support of continuing pre-clinical trials at UCLA, NeuroSigma entered into a contract with UCLA to fund the development of prototype TFN-covered stents for use in upcoming human trials.

Peripheral Artery Disease (PAD) Stent

Ten million Americans suffer from PAD, a common circulatory problem in which narrowing of arteries can lead to a reduction in blood flow to the limbs and a possible precursor to amputation or death from heart attack and stroke.

The license with UCLA also includes the use of TFN-covered stents for the treatment of PAD.  Since 2009 under an NIH Challenge Grant, UCLA has been conducting in vivo pre-clinical trials to demonstrate that its TFN-covered stents may eventually be used for the treatment of PAD by remaining patent even in vessels as small as 3 millimeters.  A unique surface treatment of UCLA's TFN film provides super-hydrophylic properties, which greatly reduces the adherence of platelets.

CAUTION: NSVascular's TFN-covered stents are investigational devices and at this time are limited by United States law for investigational pre-clinical use only.

About NeuroSigma, Inc.

NeuroSigma is a Los Angeles-based medical technology company established to in-license and develop early stage technologies with the potential to transform medical practice.  Currently we have a specific focus on neuromodulation and through our majority-owned subsidiary, NSVascular, on Thin-Film Nitinol covered stents for endovascular applications.  NeuroSigma employs two therapy platforms: Trigeminal Nerve Stimulation (TNS) and Deep Brain Stimulation (DBS).  NeuroSigma has amassed significant intellectual property licensed on an exclusive basis from the University of California, Los Angeles (UCLA), including potential therapies for epilepsy, depression and post-traumatic stress disorder (PTSD) via TNS and for PTSD, obesity and cachexia via DB
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