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NSVascular, Inc., a NeuroSigma Subsidiary, Signs an Exclusive License Covering UCLA's Thin-Film Nitinol (TFN) Stent Technology for Endovascular Applications
Date:7/18/2011

with a new team of engineers and physicians from UCLA," said Lodwrick M. Cook, Chairman of NeuroSigma.

"The successful convergence of engineering and medicine is exemplified by the accomplishments of this team.  We would like to applaud these accomplishments and the dedication on the medical side of Drs. Fernando Vinuela, Dan Levi, David Rigberg and Colin Kealey and on the engineering side of Professors Greg Carman and Youngjae Chun and Dr. K.P. Mohanchandra, to transition TFN-covered stents from the laboratory to the clinic and welcome them as co-founders and scientific advisors of NSVascular," said Leon Ekchian, Ph.D., President and CEO of NeuroSigma.

Intracranial Aneurysm (IA) Flow-Diverting Stent

Intracranial aneurysms result from weaknesses in cerebral blood vessels, which can rupture and lead to stroke and death.  It is estimated that up to one in fifteen people in the United States develop a brain aneurysm during their lifetime.  The traditional method of surgical clipping to treat brain aneurysms is very invasive requiring removal of a section of the skull.  Since 1995, endovascular coils, have gained popularity, now accounting for the majority of current procedures.

"Pre-clinical in vivo testing has shown a remarkable 100% aneurysm occlusion rate within minutes of treatment, an achievement unmatched by competing flow-diverting technologies," said Fernando Vinuela, M.D., Director of UCLA's Division of Interventional Neuroradiology and a co-founder and scientific advisor to NSVascular.  "Furthermore, our TFN-covered flow-diverting stent keeps the flexibility of the delivery system allowing safer distal intracranial navigation and stenting of a larger number of aneurysms," added Vinuela.  

The company believes that flow-diverting stents represent one of the fastest growing segments of the neurovascular market and may supplant intracranial coiling as the preferred treatment for cer
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SOURCE NeuroSigma, Inc.
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