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NDRI Has Been Awarded $3.59 Million From the National Institutes of Health, 'The Directors Common Fund' to Provide Human Tissue for 'GTEx,' the New Genotype-Tissue Expression Project
Date:10/13/2010

hical Legal and Social Issues, which will provide an assessment of participant feedback on the consent process for the project.

The GTEx project is a 2.5-year pilot with the primary goal of testing the feasibility of collecting high-quality RNA and DNA from 30-50 tissues recovered from each of approximately 160 consented normal donors identified through low post-mortem interval autopsy or organ transplant settings. A small subset of tissues will be collected from a targeted population of 160 consented normal surgical patients to compare to post-mortem derived tissues. One of the goals of the pilot project is to test all systems that identify consented donors and the feasibility of timely recovery of a large number of biospecimens from each of many donors. The future plan is to expand the GTEx project to involve some 1000 donors.

"This is an amazing opportunity for NDRI and for the scientific community," stated Lee Ducat, founder and president of NDRI.  "This year is NDRI's 30th anniversary year providing quality donated human tissues to research studies nationally and internationally. We are tremendously proud to be a part of this important National Institutes of Health initiative." Ducat added that NDRI is in the "start-up" phase of the GTEx program and is prepared to move full speed ahead on this new and exciting GTEx initiative.  "We view this cutting-edge program as a major challenge in terms of consent issues, the number of donors required, the number of specimens requested from each donor and quality control issues," said Ducat.  "At the same time, we are confident in our NDRI staff expertise to administer the program and in our 'partners' ability to complete all tasks required."

Since 1980, NDRI has served a vital need providing some 5,000 scientists with more than 300,000 human biomaterials, leading to more than 2,600 papers published in scholarly journals on diseases from diabetes to cancer to HIV an
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SOURCE NDRI, The National Disease Research Interchange
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