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NDRI Has Been Awarded $3.59 Million From the National Institutes of Health, 'The Directors Common Fund' to Provide Human Tissue for 'GTEx,' the New Genotype-Tissue Expression Project
Date:10/13/2010

PHILADELPHIA, Oct. 13 /PRNewswire/ -- NDRI, The National Disease Research Interchange, a Philadelphia-based national human tissue center celebrating its 30th year, today announced it has been awarded a $3.59 million subcontract from the National Institutes of Health (NIH) for the new cutting-edge project "GTEx" (Genotype-Tissue Expression). The funds for the 30-month project are provided by the NIH Common Fund and awarded through NCI (the National Cancer Institute), NIMH (the National Institute of Mental Health) and NHGRI (the National Human Genome Research Institute). The goal of this "Pilot Project" is to test systems that will enable scientific investigation of the relationship between genetic variation and regulation of gene expression on a tissue-specific basis.

"GTEx will begin to provide researchers with a comprehensive view of genetic variation and a more precise understanding of how it affects genes critical to the normal function of tissue and organs," said NIH Director, Francis S. Collins, MD, PhD. "This resource will add a new dimension to our understanding of human biology and the mechanisms that lead to disease."

This subcontract has been awarded to NDRI to utilize its established systems and partners to collect multiple human tissues from a large number of consented normal donors, which will then be characterized for genetic variability and genotyping. For the GTEx pilot, NDRI will partner with the Philadelphia-based "Gift of Life Donor Program" under the supervision of Rick Hasz, Vice President of Clinical Services, Drexel University College of Medicine, Fernando U. Garcia, M.D., Regional Director of Anatomic Pathology and in Virginia, LifeNet Health, Gary Walters, Senior Director of Tissue Recovery and Kidney Perfusion. In addition, for the GTEx project, NDRI will partner with Laura Siminoff, Ph.D., Professor and Chair of the Department of Social and Behavioral Health at Virginia Commonwealth University for a Study of Associated Et
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SOURCE NDRI, The National Disease Research Interchange
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