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Multiple Programs from Merrimack Pharmaceuticals' Pipeline to be Presented at the 2011 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
Date:11/11/2011

ion of MM-111 and lapatinib dosing regimens using mathematical modeling and quantitative biology

Poster Session: Pharmacokinetics and Pharmacodynamics 3

Number: C118

Date/Time: Tuesday, Nov 15, 12:30 PM – 2:30 PM

Location: West Hall, Level One, Moscone Convention Center WestMM-302MM-302 is a nanotherapeutic encapsulation of doxorubicin designed to target ErbB2 (HER2) overexpressing cancer cells, while limiting uptake into non-target cells.Title:  HER2-targeted liposomal doxorubicin, MM-302, has a favorable cardiosafety profile in preclinical models

Poster Session: Novel Assay Technology

Number: C90

Date/Time: Tuesday, Nov 15, 2011, 12:30 PM – 2:30 PM

Location: West Hall, Level One, Moscone Center WestMM-151MM-151 is a mixture of three fully human monoclonal antibodies directed against distinct non-overlapping epitopes in EGFR.Title:  Elucidating mechanisms of action of MM-151, a mixture of three human antibody antagonists targeting EGFR

Poster Session: Therapeutic Agents: Biological 1

Number: A210

Date/Time: Sunday, Nov 13, 2011, 12:30 PM – 2:30 PM

Location: West Hall, Level One, Moscone Center WestTitle:  Therapeutically targeting high-affinity ligand activation of EGFR with MM-151, an oligoclonal therapeutic

Poster Session: EGFR / Her2

Number: A144

Date/Time: Sunday, Nov 13, 2011, 12:30 PM – 2:30 PM

Location: West Hall, Level One, Moscone Center WestMM-141MM-141 is a comprehensive IGF-1R signaling inhibitor that is designed to address the redundancies that occur in tumors where both IGF-1R and ErbB3 (HER3) are activated, an approach intended to improve patient response by blocking survival signaling promoted by two separate pathways. Title:  Therapeutically targeting redundant, growth
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