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MultiCell Technologies Granted U.S. Patent Covering Therapeutics Which Fight Virus Infection And Cancer
Date:8/25/2014

producing virus antigen-specific T-cells resulting in significantly reduced virus levels present in the animal.

MultiCell is developing MCT-465 and MCT-475 for the treatment of hepatitis B virus infection and hepatitis C virus infection, and for the treatment of certain cancers. 

Chronic hepatitis B and chronic hepatitis C virus infection are recognized as major factors worldwide that increase the risk of hepatocellular carcinoma.  According to the U.S. National Cancer Institute (NCI), chronic hepatitis B virus infection and chronic hepatitis C virus infection account for about 30% to 40% of all reported USA cases of hepatocellular carcinoma.

Treatment of hepatocellular carcinoma, the most common form of primary liver cancer, represents a major unmet medical need.   Hepatocellular carcinoma is a leading cause of cancer death worldwide, and is the fourth most common cancer in the world.  Over 1 million cases of hepatocellular carcinoma are reported annually worldwide.  Current approaches for treatment of hepatocellular carcinoma are of limited efficacy.  According to the NCI, only 16% of patients diagnosed with primary liver cancer survive longer than 5 years.

MultiCell is also developing MCT-485, a very small dsRNA therapeutic, thought to target cancer by delivering a cytotoxic effect to only those cells having the highest tumor initiating capability that are part of the cancerous process such as cancer stem cells and tumor initiating cells.  MCT-485 appears to have no effect on cells not directly involved in the process of relapse, progression and metastasis of cancer.  MCT-485 appears to exert a preferential biological activity on liver cancer cells while showing no effect on normal liver cells.

About MultiCell Technologies, Inc.

MultiCell Technologies, Inc. is a clinical-stage biopharmaceutical company developing novel therapeutics and discovery tool
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SOURCE MultiCell Technologies, Inc.
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