Navigation Links
Mount Sinai Researchers Discover That Fasting Reduces Inflammation and Improves Chronic Inflammatory Diseases
Date:8/23/2019

Fasting regimens have gained public and scientific interest in recent years, but fasting shouldn’t be dismissed as a fad. In a study published in Cell, Mount Sinai researchers found that fasting reduces inflammation and improves chronic inflammatory diseases without affecting the immune system’s response to acute infections.

While acute inflammation is a normal immune process that helps fight off infections, chronic inflammation can have serious consequences for health, including heart disease, diabetes, cancer, multiple sclerosis, and inflammatory bowel diseases.

“Caloric restriction is known to improve inflammatory and autoimmune diseases, but the mechanisms by which reduced caloric intake controls inflammation have been poorly understood,” said senior author Miriam Merad, MD, PhD, Director of the Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai.

Working with human and mouse immune cells, Dr. Merad and colleagues showed that intermittent fasting reduced the release of pro-inflammatory cells called “monocytes” in blood circulation. Further investigations revealed that during periods of fasting, these cells go into “sleep mode” and are less inflammatory than monocytes found in those who were fed.

“Monocytes are highly inflammatory immune cells that can cause serious tissue damage, and the population has seen an increasing amount in their blood circulation as a result of eating habits that humans have acquired in recent centuries,” said Dr. Merad.

“Considering the broad spectrum of diseases that are caused by chronic inflammation and the increasing number of patients affected by these diseases, there is an enormous potential in investigating the anti-inflammatory effects of fasting,” said first author Stefan Jordan, PhD, a postdoctoral fellow in the Department of Oncological Sciences at the Icahn School of Medicine at Mount Sinai.

Researchers plan to continue trying to decipher the molecular mechanisms by which fasting improves inflammatory diseases, which could lead to novel preventive therapeutic strategies for the treatment of many human diseases.

About Mount Sinai Health System
The Mount Sinai Health System is New York City's largest integrated delivery system, encompassing eight hospitals, a leading medical school, and a vast network of ambulatory practices throughout the greater New York region. Mount Sinai's vision is to produce the safest care, the highest quality, the highest satisfaction, the best access and the best value of any health system in the nation. The Health System includes approximately 7,480 primary and specialty care physicians; 11 joint-venture ambulatory surgery centers; more than 410 ambulatory practices throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and 31 affiliated community health centers. The Icahn School of Medicine is one of three medical schools that have earned distinction by multiple indicators: ranked in the top 20 by U.S. News & World Report's "Best Medical Schools", aligned with a U.S. News & World Report's "Honor Roll" Hospital, No. 12 in the nation for National Institutes of Health funding, and among the top 10 most innovative research institutions as ranked by the journal Nature in its Nature Innovation Index. This reflects a special level of excellence in education, clinical practice, and research. The Mount Sinai Hospital is ranked No. 14 on U.S. News & World Report's "Honor Roll" of top U.S. hospitals; it is one of the nation's top 20 hospitals in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Geriatrics, Gynecology, Nephrology, Neurology/Neurosurgery, and Orthopedics in the 2019-2020 "Best Hospitals" issue. Mount Sinai's Kravis Children's Hospital also is ranked nationally in five out of ten pediatric specialties by U.S. News & World Report. The New York Eye and Ear Infirmary of Mount Sinai is ranked 12th nationally for Ophthalmology and the South Nassau Communities Hospital is ranked 35th nationally for Urology. Mount Sinai Beth Israel, Mount Sinai St. Luke's, Mount Sinai West, and South Nassau Communities Hospital are ranked regionally.

For more information, visit https://www.mountsinai.org or find Mount Sinai on Facebook, Twitter and YouTube.

Read the full story at https://www.prweb.com/releases/mount_sinai_researchers_discover_that_fasting_reduces_inflammation_and_improves_chronic_inflammatory_diseases/prweb16524341.htm.


'/>"/>
Source: PRWeb
Copyright©2019 Vocus, Inc.
All rights reserved


Related medicine technology :

1. Transvaginal Mesh Settlement Funding Amounts Increased At Legal-Bay
2. New Intermountain Healthcare Transformation Lab To Feature Soteras ViSi Mobile System
3. Xi3 Corporation Signs Collaboration Agreement with Intermountain Healthcare as Founding Member of Intermountains New Healthcare Transformation Lab
4. Sam Solakyan announces Paramount Management Services is now a full-scale MSO
5. Hospira Unveils New Quality Laboratory and Investments at Rocky Mount, N.C., Plant
6. JACO WS-14 Wall Mounted Tablet Security System Announcement
7. Valeant Pharmaceuticals Announced Redemption Of $450 Million Aggregate Principal Amount Of Its Outstanding 6.50% Senior Notes Due 2016
8. Berg e la Icahn School of Medicine presso Mount Sinai hanno annunciato una partnership per Ricerca e Sviluppo per la scoperta e lo sviluppo di farmaci
9. Berg und die Icahn School of Medicine at Mount Sinai geben F&E-Partnerschaft zur Erforschung und Entwicklung neuer Arzneimittel bekannt
10. Berg en Icahn School of Medicine van het Mount Sinai kondigen R&D- partnerschap aan voor ontdekking en ontwikkeling van geneesmiddelen
11. Transparency Life Sciences Partners With Oncology Researchers At Icahn School Of Medicine At Mount Sinai To Assess Metformin In Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/14/2019)... ... September 13, 2019 , ... ... in Montreal provided a plethora of breakthrough research studies including several cancer ... to detect breast cancer, response prediction of cancer immunotherapies and whole body, ...
(Date:9/14/2019)... ... 2019 , ... CME4Life, a leading provider of physician assistant ... at a world record “Longest Medical Lecture” on November 16, 2019. The lecture ... CME credits in 30 consecutive hours. ?The conference will take place at The ...
(Date:9/11/2019)... ... September 12, 2019 , ... Understanding the Drug Supply ... Webinar, Thursday, Sept. 26, 2019, 1:30-3:00 p.m. EDT, https://www.fdanews.com/understanding-the-dscsa , Need ... the company clear on nuances of the guidelines regulating the drug supply chain? ...
Breaking Medicine Technology:
(Date:9/11/2019)... ... September 11, 2019 , ... Ahipoki is excited to announce a new vegan ... to vegans, vegetarians, pescatarians and poke bowl fans alike. Ahimi is made of ... its meaty texture similar to tuna, Ahipoki customers will now have a ...
(Date:9/11/2019)... ... September 10, 2019 , ... Women’s Excellence is excited to announce ... at 32686 Woodward Ave, Suite 103, Royal Oak, MI 48073 in the heart of ... offers comprehensive women’s health services in a contemporary, spa-like atmosphere. We are thrilled ...
(Date:9/11/2019)... ... September 10, 2019 , ... Four Shriners for ... physicians have been recognized among the best doctors in the San Gabriel Valley ... Robert H. Cho, M.D. – Chief of Staff, scoliosis, spinal deformity ...
(Date:9/11/2019)... (PRWEB) , ... September 10, 2019 , ... ... provide critical support to the most vulnerable communities impacted by Hurricane Dorian. ... in South Carolina, the Episcopal Diocese of Georgia, and the Episcopal Farmworker Ministry, ...
(Date:9/9/2019)... HERNDON, Va. (PRWEB) , ... September 09, 2019 ... ... North America, today announced that IP Access International will integrate the iDirect iQ ... terminal, a portable and hybrid communications solution for first responders. The iQ 200 ...
Breaking Medicine News(10 mins):