Navigation Links
Mortality Data Presented for Patients Treated with Efient®/Effient® (Prasugrel) Who Underwent Isolated Coronary Artery Bypass Surgery
Date:11/16/2010

CHICAGO, Nov. 16, 2010 /PRNewswire-FirstCall/ -- New results from an observational substudy from TRITON–TIMI 38 presented today at the American Heart Association (AHA) Scientific Sessions annual meeting showed that patients treated with Efient®/Effient® (prasugrel) prior to coronary artery bypass graft surgery (CABG) had a reduced overall mortality rate compared to patients treated with Plavix® (clopidogrel) (2.3 percent versus 8.7 percent respectively, p=0.016).(1)

This retrospective analysis involved 346 patients with acute coronary syndrome (ACS) who had received either study drug and subsequently underwent isolated CABG at some point during the 15-month TRITON-TIMI 38 trial.(2)  

In addition to all-cause mortality, this same analysis found that the risk-adjusted rate of cardiovascular death at 30 days was also lower in patients treated with prasugrel compared with those receiving clopidogrel (0.6 percent versus 5.8 percent respectively, p=0.038).(3)  Prasugrel-treated patients experienced a statistically significantly higher volume of chest tube blood loss at 12 hours post-CABG compared to the clopidogrel-treated patients (655 +/- 580 milliliters with Effient versus 503 +/- 378 milliliters with clopidogrel.(1)

"This analysis showed that prasugrel was associated with a significantly lower mortality rate compared with clopidogrel among these CABG patients but with a significantly higher risk of serious bleeding events," said Peter K. Smith, M.D., professor of surgery and division chief of Cardiovascular and Thoracic Surgery at Duke University Medical Center and lead investigator for the retrospective CABG analysis. "This analysis helps better define the risk of mortality for physicians who care for the ACS patients who may be targeted for PCI but end up undergoing CABG instead."

The prasugrel prescribing information includes a warning and precaution against starting prasugrel in patients likely to unde
'/>"/>

SOURCE Eli Lilly and Company
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Adding INSPRA® (eplerenone) to Standard Therapy Significantly Reduces the Risk of CV Mortality and Morbidity in Patients With Chronic Heart Failure With Mild Symptoms, Study Shows
2. Robotic Prostatectomy Expert Dr. David Samadi Talks About Big Strides in the Fight Against Prostate Cancer - Mortality Rate Declines 45%
3. Analysis Shows Novartis Drug TOBI® Associated With Reduced Mortality in Cystic Fibrosis Patients With Common Lung Infection
4. Two New Clinical Studies Show That Limited Exposure to Blood Transfusion Significantly Increases Morbidity and Mortality After Surgery
5. Increased Mortality Associated With Nocturia
6. Unemployment, Health Care Spending Affect Mortality
7. Preliminary Data From Experimental Study Demonstrate Increased Mortality in Stroke Patients Treated With Epoetin Alfa
8. n-3 PUFAs Reduce Mortality and Hospital Admissions in Patients With Symptomatic Heart Failure
9. Study Shows Use of AdvanDxs PNA FISH(TM) Test was Associated with an 82% Reduction in Intensive Care Unit Mortality Rates from Staphylococcus aureus Bloodstream Infections
10. New Analyses of Data From RE-LY Trial, Involving Oral Anticoagulant Pradaxa, to be Presented at American Heart Associations Scientific Sessions
11. Ardea Announces Data on MEK Inhibitor BAY 86-9766 (RDEA119) to be Presented at EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/1/2015)... , July 1, 2015 Rock Creek ... company focused on chronic inflammatory disease and neurologic disorders, ... principle study with anatabine citrate, the Company,s lead compound. ... dose of anatabine citrate can significantly inhibit the activation ... The Company is developing this compound in a Phase ...
(Date:7/1/2015)... Pa. , July 1, 2015 ... fully integrated specialty pharmaceutical company focused on developing, ... that Bob Radie , president and chief ... conferences this summer. He will provide an update ... (ketorolac tromethamine) Nasal Spray, approved product ...
(Date:7/1/2015)... 1, 2015 New exchange plan enrollees spent ... compared to the same time a year ago, according ... ESRX ) Exchange Pulse™ report, released today. ... the number of new exchange plan enrollees who used ... the first quarter of 2015. However, when evaluating exchange ...
Breaking Medicine Technology:Rock Creek Pharmaceuticals Reports Human Proof of Principle Study of Lead Compound Demonstrating Inhibition of Inflammatory Markers In White Blood Cells 2Rock Creek Pharmaceuticals Reports Human Proof of Principle Study of Lead Compound Demonstrating Inhibition of Inflammatory Markers In White Blood Cells 3Rock Creek Pharmaceuticals Reports Human Proof of Principle Study of Lead Compound Demonstrating Inhibition of Inflammatory Markers In White Blood Cells 4Egalet to Present at Upcoming Conferences This Summer 2Egalet to Present at Upcoming Conferences This Summer 3Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 2Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 3Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 4Express Scripts Provides First Look at 2015 Public Exchange Pharmacy Trends 5
... Clinic Service Corporation (CSC), the leader in Colorado ... an agreement to be the exclusive provider of medical ... "We are thrilled to add this practice or our ... and Metabolism is an endocrinology leader and pioneer. He ...
... Oct. 1 In a continued effort to keep ... Cross, State Sponsored Business launched an innovative on-line Body ... wheel and web-based interactive practice sessions to help provide ... online BMI training program builds on Anthem,s efforts which ...
Cached Medicine Technology:Anthem Blue Cross Takes BMI Training Virtual with New Online Capability 2Anthem Blue Cross Takes BMI Training Virtual with New Online Capability 3
(Date:7/1/2015)... ... July 01, 2015 , ... After conducting a nationwide ... Tri-City Medical Center in Oceanside, Calif., has hired Cheryle Bernard-Shaw as ... organization-wide compliance adaptation efforts and growing a focus on risk management, Bernard-Shaw will ...
(Date:7/1/2015)... , ... July 01, 2015 , ... The Recovery ... with PAPRS, welcomed Scott Stossel, editor of The Atlantic, as a keynote on June ... combatting anxiety, and how telling his personal story added power and reach to the ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... of southeast Alabama, southwest Georgia and the Florida Panhandle, the regional southeast ... primary secure text messaging and clinical communications workflow solution provider. TelmedIQ, a ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... space, created a web-based resource where legal cannabis startups can interact ... visionary entrepreneurs and medical marijuana advocates looking to strategically enter and capitalize on ...
(Date:7/1/2015)... VA (PRWEB) , ... July 01, 2015 , ... Effective ... new board members and officers for 2015-2016. The annual board election process has been ... on a volunteer basis. , Suzanne Taylor, BS, FRBMA, succeeds Keith E. ...
Breaking Medicine News(10 mins):Health News:Tri-City Medical Center Hires New Chief Compliance Officer 2Health News:Tri-City Medical Center Hires New Chief Compliance Officer 3Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 2Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 3Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 4Health News:Scott Stossel, Editor of The Atlantic, Addressed Mental Health Professionals on Reducing Prejudice and Discrimination 5Health News:Southeast Alabama Community Health System Chooses TelmedIQ to Meet Secure Text Messaging Challenges for Healthcare 2Health News:First Harvest Financial Partners in Launch of Legal Medical Cannabis Documentary Initiative 2Health News:First Harvest Financial Partners in Launch of Legal Medical Cannabis Documentary Initiative 3Health News:Radiology Business Management Association Announces Board of Directors and Officers for 2015-2016 2Health News:Radiology Business Management Association Announces Board of Directors and Officers for 2015-2016 3Health News:Radiology Business Management Association Announces Board of Directors and Officers for 2015-2016 4
... Director of the Neuroscience Center of Excellence, Boyd Professor, ... Retinal Degenerative Diseases Research at LSU Health Sciences Center ... an omega three fatty acid in the diet protects ... resulting from a gene mutation in neurodegenerative diseases like ...
... on April 29th at 2pm EST/ 11am PST , ... (PRWEB) April ... hospital executives across North America think having a medical home strategy is ... will the HITECH Act impact your decision on which projects to focus ...
... a new nonprofit organization dedicated to supporting ... today, debuting its web site ( www.autismsciencefoundation.org ... Days" fundraising drive. ASF,s mission is to ... other assistance to scientists and organizations conducting, ...
... is recommending radon gas testing, remediation, and radon removal systems for ... towns affected by radon gas are Denver, Littleton, Boulder, Broomfield, Aurora, ... For homes with radon levels of 4.0 or higher, radon mitigation ... ...
... IRVINE, Calif., April 17 ISTA Pharmaceuticals, Inc. (Nasdaq: ... results on May 7, 2009, and will host a conference call ... p.m. Eastern Time. , , Date: Thursday, ... Conference call access:, Internet: www.istavision.com, ...
... Care Center and Surgical Care Affiliates, LLC have recently ... for use in each of their four operating rooms. ... and throat surgical teams as they perform knee, shoulder, ... procedures. Physicians, Surgical Care Center of Winter Park ...
Cached Medicine News:Health News:LSUHSC research shows fish oil protects against diseases like Parkinson's 2Health News:Autism Science Foundation Launches Operations; New Advocacy Group Will Focus on Non-vaccine-related Autism Research 2Health News:Autism Science Foundation Launches Operations; New Advocacy Group Will Focus on Non-vaccine-related Autism Research 3Health News:Autism Science Foundation Launches Operations; New Advocacy Group Will Focus on Non-vaccine-related Autism Research 4Health News:Radon Mitigation and Remediation Systems Recommended in Denver, Littleton, Broomfield Colorado Homes 2Health News:Radon Mitigation and Remediation Systems Recommended in Denver, Littleton, Broomfield Colorado Homes 3Health News:Physicians' Surgical Care Center of Winter Park and Surgical Care Affiliates (SCA) Are Proud to Announce New State of the Art Equipment 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: