Navigation Links
Mortality Data Presented for Patients Treated with Efient®/Effient® (Prasugrel) Who Underwent Isolated Coronary Artery Bypass Surgery
Date:11/16/2010

CHICAGO, Nov. 16, 2010 /PRNewswire-FirstCall/ -- New results from an observational substudy from TRITON–TIMI 38 presented today at the American Heart Association (AHA) Scientific Sessions annual meeting showed that patients treated with Efient®/Effient® (prasugrel) prior to coronary artery bypass graft surgery (CABG) had a reduced overall mortality rate compared to patients treated with Plavix® (clopidogrel) (2.3 percent versus 8.7 percent respectively, p=0.016).(1)

This retrospective analysis involved 346 patients with acute coronary syndrome (ACS) who had received either study drug and subsequently underwent isolated CABG at some point during the 15-month TRITON-TIMI 38 trial.(2)  

In addition to all-cause mortality, this same analysis found that the risk-adjusted rate of cardiovascular death at 30 days was also lower in patients treated with prasugrel compared with those receiving clopidogrel (0.6 percent versus 5.8 percent respectively, p=0.038).(3)  Prasugrel-treated patients experienced a statistically significantly higher volume of chest tube blood loss at 12 hours post-CABG compared to the clopidogrel-treated patients (655 +/- 580 milliliters with Effient versus 503 +/- 378 milliliters with clopidogrel.(1)

"This analysis showed that prasugrel was associated with a significantly lower mortality rate compared with clopidogrel among these CABG patients but with a significantly higher risk of serious bleeding events," said Peter K. Smith, M.D., professor of surgery and division chief of Cardiovascular and Thoracic Surgery at Duke University Medical Center and lead investigator for the retrospective CABG analysis. "This analysis helps better define the risk of mortality for physicians who care for the ACS patients who may be targeted for PCI but end up undergoing CABG instead."

The prasugrel prescribing information includes a warning and precaution against starting prasugrel in patients likely to unde
'/>"/>

SOURCE Eli Lilly and Company
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Adding INSPRA® (eplerenone) to Standard Therapy Significantly Reduces the Risk of CV Mortality and Morbidity in Patients With Chronic Heart Failure With Mild Symptoms, Study Shows
2. Robotic Prostatectomy Expert Dr. David Samadi Talks About Big Strides in the Fight Against Prostate Cancer - Mortality Rate Declines 45%
3. Analysis Shows Novartis Drug TOBI® Associated With Reduced Mortality in Cystic Fibrosis Patients With Common Lung Infection
4. Two New Clinical Studies Show That Limited Exposure to Blood Transfusion Significantly Increases Morbidity and Mortality After Surgery
5. Increased Mortality Associated With Nocturia
6. Unemployment, Health Care Spending Affect Mortality
7. Preliminary Data From Experimental Study Demonstrate Increased Mortality in Stroke Patients Treated With Epoetin Alfa
8. n-3 PUFAs Reduce Mortality and Hospital Admissions in Patients With Symptomatic Heart Failure
9. Study Shows Use of AdvanDxs PNA FISH(TM) Test was Associated with an 82% Reduction in Intensive Care Unit Mortality Rates from Staphylococcus aureus Bloodstream Infections
10. New Analyses of Data From RE-LY Trial, Involving Oral Anticoagulant Pradaxa, to be Presented at American Heart Associations Scientific Sessions
11. Ardea Announces Data on MEK Inhibitor BAY 86-9766 (RDEA119) to be Presented at EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... ALBANY, New York , July 11, 2014 /PRNewswire/ ... published by Transparency Market Research "Endoscopy Devices Market (Endoscopes, ... Analysis, Size, Share, Growth, Trends and Forecast, 2013-2019" the ... billion in 2012 and is expected to grow at ... reach an estimated value of USD 36.9 billion in ...
(Date:7/11/2014)... , July 11, 2014 ... to Safety & Health Expo 2014 were ... move to London , ... attending exhibition.          ... http://photos.prnewswire.com/prnh/20140711/696892-a )      (Photo: ...
(Date:7/10/2014)... , 11. Juli 2014  Dilon ... für die molekulare Bildgebung, einschließlich molekularer ... die CE-Zulassung für sein Navigator ® ... Dilon das Produkt jetzt europaweit vertreiben. ... Großteil der europäischen Länder ausgedehnt und ...
Breaking Medicine Technology:Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 2UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 3UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 4Dilon erhält CE-Zulassung für sein Navigator-Gamma-Sondensystem 2
... BellaNovus Development Company LLC, a medical design ... the Ouchless™ Needle Collection. The devices provide doctors ... creams and ice currently used to minimize localized ... and dermal fillers. Offered in three models, Ouchless™ ...
... CIVCO Medical Solutions is showcasing its RFSuite RFID tracking ... also hosting an RFSuite Symposium Monday, August 1st, from ... the Fairmont Waterfront, Vancouver. The event will include lunch, ... Click here to view the invitation and register . ...
Cached Medicine Technology:New Ouchless™ Needle Collection Revolutionizes Wrinkle Treatments With State-of-the-Art Pain Reducing Technology 2CIVCO Showcases RFSuite RFID Tracking and Verification System at AAPM 2011 Booth #817 2CIVCO Showcases RFSuite RFID Tracking and Verification System at AAPM 2011 Booth #817 3
(Date:7/14/2014)... Carepoint has been designed specifically to ... an intuitive interface for recording, sending, displaying and ... and reporting features. , Hall mc - an ... with Rebecca de Witte to create this exciting ... Carepoint provides seamless, real-time communication between ...
(Date:7/14/2014)... mental activity, and moderate physical activity in middle ... Alzheimer,s disease and dementia in later life, according ... Association International Conference 2014 (AAIC 2014) in Copenhagen. ... showed that sleep problems especially when combined ... dementia risk in veterans. Additionally, in a population ...
(Date:7/14/2014)... 2014 Spine Team Texas ... care—from diagnosis to treatment and recovery. Currently all physical ... in or training for certification in The McKenzie Method. ... completed the extensive program. , “We require certification of ... results in better outcomes for spine pain patients,” said ...
(Date:7/14/2014)... 2014 Cadeon Associates Inc. ... into Money,” today announced that it has joined ... that helps partners resell, deploy, and develop solutions ... platform. TIBCO Software Inc. is a global leader ... Spotfire analytics, providing businesses the ability to capture ...
(Date:7/13/2014)... TopDresses100.com, a popular dress company in the global market, ... dresses to its product line. According to the ... guaranteed to be quality made. Now, they are offered ... has a wide variety of elegant dresses for customers ... stock and ready to ship. As an innovation-based supplier, ...
Breaking Medicine News(10 mins):Health News:Home Health Care Professional and Marketing Firm Team Up to Create New Homecare Communication App 2Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 2Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 3Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 4Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 5Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 6Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 2Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 3Health News:Cadeon Associates Inc. Joins TIBCO Spotfire Partner Network 2Health News:Cadeon Associates Inc. Joins TIBCO Spotfire Partner Network 3Health News:Cheap Multi-colored Quinceanera Dresses From TopDresses100.com 2
... (IANS) While the Nepalese government's attention is focused on ... among migrant labourers, intravenous drug users and sex ... groups in the country with the rate of infection ... to Nepal's National Centre for AIDS and STD (sexually ...
... of dengue cases in affluent Singapore has surpassed an epidemic ... . ,The National Environment Agency (NEA) and ... that the weekly number of dengue cases reported last week ... week. This number breached the "epidemic threshold" of 378 cases ...
... exposed themselves outside the Supreme Court on Tuesday in ... legal challenge against advertising restrictions . ,The ... had all raised healthy children on natural breast milk. ... their breasts. ,"Infant formula is dangerous," ...
... John Travolta has blamed psychotropic drugs for the Virginia Tech and ... at the whole story , it has not so much to ... that if you analyze most of the school shootings, it is ... it," New York Post quoted Travolta, as saying. ,The ...
... increasingly monitoring what their kids watch on TV or the ... national survey of 1,008 parents of children ages 2-17, a ... their children's media use, while only 18 percent say that ... concerned about a lot of what they see in the ...
... heat content on interannual-to-decadal time scales much more ... an Indian scientist has revealed. ,Krishna ... Model Diagnosis and Intercomparison (PCMDI), and now at ... find the apparent discrepancies between modelled and observed ...
Cached Medicine News:Health News:Huge Rise in AIDS Cases Among Nepal Housewives 2Health News:Filipino Mothers Go Bare Protesting Against Milk Formula Companies 2Health News:Parents are More Concerned on What Their Kids Watch 2Health News:IIT Delhi Scientist Finds Climate Models Consistent With Ocean Warming Observations 2
... Easy Breeze Air Gel Dryer : Dry up ... 24 gels 8 10 cm without a ... rapid drying, or no heat for controlled drying ... transparent, dried gels. Add and remove gels at ...
Each GelAir™ system drying frame includes two main components, a plastic drying outer frame and a metal square inner frame, as well as 8 clamps per frame. Supplied as a set of two frames....
... Breeze Air Gel Dryer : Dry up to ... gels 8 10 cm without a vacuum ... drying, or no heat for controlled drying of ... dried gels. Add and remove gels at any ...
... SGD5040 Slab Gel Dryer incorporates sturdy metal housing and ... The large surface area makes it perfect for drying ... Slim Profile 40cm x 50cm (W x D) ... Rates allows you to optimize your heating ...
Medicine Products: