Navigation Links
Morphotek®, Inc. Announces Initiation of Farletuzumab Phase II Study in First-Line Treatment of Non-Small Cell Lung Cancer
Date:6/28/2011

EXTON, Pa., June 28, 2011 /PRNewswire/ -- Morphotek®, Inc., a subsidiary of Eisai Inc., announced today that it has commenced a multi-center phase II study of farletuzumab in adenocarcinoma of the lung, a type of non-small cell lung cancer (NSCLC). The study will evaluate farletuzumab, a monoclonal antibody that specifically binds to folate receptor-alpha (FRA), with the physician's choice of one of three standard platinum-containing doublets that are approved and recommended for first-line metastatic lung cancer patients.

The trial is designed as a randomized, double-blind, placebo-controlled study to determine if  farletuzumab delays the time to tumor progression when it is added to one of the standard-of-care chemotherapy options for metastatic adenocarcinoma of the lung. Secondary objectives include safety, response rate and duration of response, and overall survival benefit of patients treated with the antibody plus chemotherapy versus the chemotherapy with a placebo. The patient population includes individuals with advanced NSCLC adenocarcinoma who have tumors that over-express FRA and have not received any prior radiation or chemotherapy for curative intent of their disease. It is estimated that about three-quarters of adenocarcinoma of the lung are FRA-positive.

Morphotek expects to enroll up to 120 patients in this clinical study, which is being conducted at clinical centers globally.  As part of the study, a Morphotek-developed diagnostic kit will be used to determine patient eligibility.  

"We are excited to have initiated this global phase II study of farletuzumab in cooperation with leading physicians.  Since farletuzumab targets FRA, this personalized approach will include only those patients who could potentially benefit from therapy with the new agent," stated Julia Maltzman, M.D., Senior Director of Clinical Development at Morphotek. "NSCLC has a generally poor prognosis, so we hope that farletuzumab
'/>"/>

SOURCE Morphotek, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Morphotek®, Inc. Announces Acquisition of Tumor Targeting Assets From Transmolecular, Inc.
2. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
3. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
4. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
5. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
6. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
7. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
8. Xenomics Announces Implementation of its First Diagnostic Test for Acute Myeloid Leukemia Into Clinical Practice
9. Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results
10. Amicus Therapeutics Announces Second Quarter 2007 Financial Results
11. Genta Incorporated Announces Second Quarter 2007 Financial Results and Corporate Highlights
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... Aug. 21, 2014  Decision Resources Group finds ... Brazil and ... and commonly prescribe long-acting beta-agonist (LABA)- and long-acting ... so within current severe cost/coverage constraints. Therefore, new ... expected to launch in these countries—which will considerably ...
(Date:8/21/2014)... , Aug. 21, 2014  Seventy-one percent of Americans ... OxyContin is a serious public health and safety issue in ... from a survey released today by Repass & Partners, a ... "Americans understand the severity of the prescription medication ... progress with this very serious health situation facing our country," ...
(Date:8/21/2014)... Aug. 21, 2014  Henry Schein, Inc. (NASDAQ: ... and services to office-based dental, animal health and medical practitioners, ... conferences in September: , September 4, 2014 – ... , NY at 12:50 p.m. ET , September 8, 2014 ... New York , NY at 1:25 p.m. ET ...
Breaking Medicine Technology:Novel Fixed-Dose Combinations for COPD in Brazil and Mexico Will Compete With Well-Established Therapies in an Environment Dominated by Aggressive Cost-Control Mechanisms 2Novel Fixed-Dose Combinations for COPD in Brazil and Mexico Will Compete With Well-Established Therapies in an Environment Dominated by Aggressive Cost-Control Mechanisms 3Consumers Desperate For Measures To Curb Prescription Drug Abuse 2Consumers Desperate For Measures To Curb Prescription Drug Abuse 3Henry Schein To Present At Two Investor Conferences In September 2
... 4, 2011 /PRNewswire-Asia-FirstCall/ -- Dehaier Medical Systems Ltd. ... "Company"), an emerging leader in the development, assembly, marketing ... in China, today announced that it will release financial ... June 30, 2011 on Monday, August 15, 2011 before ...
... Medical, Inc. (OTCBB: HASC), www.mysouthernmed.com , a ... Florida, and Mississippi, announced today that the Chairman ... guaranteed the financing that was used for the ... on May 17th, 2011. As part ...
Cached Medicine Technology:Dehaier Medical to Report Second Quarter 2011 Financial Results on August 15 2HASCO Medical Chairman Provides $2 Million in Capital and a Personal Guarantee on Additional $2 Million Promissory Note 2HASCO Medical Chairman Provides $2 Million in Capital and a Personal Guarantee on Additional $2 Million Promissory Note 3
(Date:8/21/2014)... The report "Indoor Location Market ... and Navigation, Location based analytics, Location based ... Market Forecasts and Analysis (2014 - 2019)" ... into various sub-segments with an in-depth analysis ... identifies the factors driving this market, various ...
(Date:8/21/2014)... therapy for depression has the added benefit of reducing ... doctors, according to a new study by the Centre ... Institute for Clinical Evaluative Sciences (ICES). , The research ... cognitive therapy showed a significant reduction in non-mental health ... who received other types of group therapy. , ...
(Date:8/21/2014)... As part of a continuing mission to ... joined with the Alliance for Safe Online Pharmacies (ASOP) ... sale of medicines. , “Helping to ensure the quality, ... a core mission for USP and an important tool ... T. Piervincenzi, chief executive officer of USP. “The illegal ...
(Date:8/21/2014)... According to a new market report published ... Industry Analysis, Size, Share, Growth, Trends and Forecast, 2012 ... at USD 236.1 million in 2011 and is estimated ... 2018 at a CAGR of 6.3% from 2012 to ... http://www.transparencymarketresearch.com/fundus-cameras.html . , Fundus cameras market growth in ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 Tibet has ... explore the mysterious mountaintop kingdom. Prayers flags whip ... Himalayas and the low rumble of chanting monks fill ... roof of the world’, access to Tibet is challenging ... the foreign land can prove to be daunting for ...
Breaking Medicine News(10 mins):Health News:Indoor Location Market Worth $3.9 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Indoor Location Market Worth $3.9 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Indoor Location Market Worth $3.9 Billion by 2019 - New Report by MarketsandMarkets 4Health News:Mindfulness-based depression therapy reduces health care visits 2Health News:USP Joins Efforts to Halt Illegal Online Drug Sales 2Health News:Fundus Cameras Market: Product Type- Mydriatic, Non-Mydriatic, Hybrid and ROP Cameras; End Users- Hospitals, Ophthalmology Clinics and Ophthalmic & Optometrist Offices 2
... Inc. (Nasdaq:,ENMD), a clinical-stage pharmaceutical company developing therapeutics ... reported financial,results for the three months ended March ... The Company reported a net loss for ... per share, compared with a net loss of ...
... Musician/photographer captures celebrity images for non-profit hearing ... awareness ... and,official photographer of the Hear the World initiative, today introduced,his photography ... exhibit. Last night,s opening was timed to celebrate the,beginning of Better ...
... ... Healthcare, OAKLAND, Calif., May 1 With talk of a ... poll,this week illustrates that Californians will once again pay particular,attention to ... poll this week by the influential Field Institute released documented,that CNA ...
... 1 LifeStem,International, Inc., (OTC Bulletin Board: LSTM), ... life sciences company,concentrating on the collection and banking ... today announced that as of May 2, it ... trading symbol, effected a,3000 for 1 reverse stock ...
... , , THURSDAY, May 1 (HealthDay News) -- Not having money ... than those making more money, according to a study that ... scored their feelings of pain on a scale of 0 ... household incomes below $30,000 a year reported moderate to severe ...
... a Unified National Acute Coronary Syndromes Registry,to Measure ... 1 The American College of,Cardiology Foundation,s National ... Get With The Guidelines(SM),(GWTG)-Coronary Artery Disease (CAD) Registry ... national unified registry for measuring and,improving safety and ...
Cached Medicine News:Health News:EntreMed Reports First Quarter 2008 Financial Results 2Health News:EntreMed Reports First Quarter 2008 Financial Results 3Health News:EntreMed Reports First Quarter 2008 Financial Results 4Health News:Photo: Bryan Adams Unveils Hear the World Ambassadors Photo Exhibit 2Health News:Photo: Bryan Adams Unveils Hear the World Ambassadors Photo Exhibit 3Health News:Field Poll: California Nurses Association Most Favorably Viewed Group in Healthcare Arena 2Health News:Field Poll: California Nurses Association Most Favorably Viewed Group in Healthcare Arena 3Health News:CalbaTech, Inc. Officially Changes Name to LifeStem International, Inc.; Lists New Symbol (LSTM) and Launches New Web Site 2Health News:Less Money Means More Hurting 2Health News:Less Money Means More Hurting 3Health News:The American College of Cardiology Foundation's NCDR(R) and the American Heart Association's GWTG Join Forces to Fight Heart Attacks 2Health News:The American College of Cardiology Foundation's NCDR(R) and the American Heart Association's GWTG Join Forces to Fight Heart Attacks 3
... to U.S. and international engineering and ... Screw and Plating System* provides seamless ... of use for open reduction internal ... TC-100 system works well beyond the ...
... The Alphatec Small Fragment ... wide range of fractures, including ... distal humerus, distal radius, distal ... malleolus, metatarsals, and metacarpals. The ...
Stainless steel threaded Steinman Pins available in point types A,D, E, and F....
Round Bevel-Point Pin Sets available in 2.3mm, 3.1mm, 4.7mm, and 6.3mm sizes....
Medicine Products: