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More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies
Date:12/3/2008

ct #1005: Saturday, December 6, 2008; 5:30 PM PST)
  • Phase IA/II Study of Oral Panobinostat (LBH589), a Novel Pan-Deacetylase Inhibitor (DACi) Demonstrating Efficacy in Patients with Advanced Hematologic Malignancies (ASH Abstract #958: Saturday, December 6, 2008; 5:30 PM PST)
  • A Phase II Study of Oral Panobinostat (LBH589) in Adult Patients with Advanced Refractory Multiple Myeloma (ASH Abstract #2774: Sunday, December 7, 2008; 6:00 PM PST)

    • Other highlights of data to be presented at SABCS include:

    RAD001

    • Multicenter Phase I clinical trial of daily and weekly RAD001 (everolimus) in combination with vinorelbine and trastuzumab in HER-2-overexpressing metastatic breast cancer with prior resistance to trastuzumab (SABCSAbstract #406: Friday, December 12, 2008; 7:00 - 9:00 AM CST)
    • RAD001 (everolimus) in combination with weekly paclitaxel and trastuzumab in patients with HER-2-overexpressing metastatic breast cancer with prior resistance to trastuzumab: a multicenter Phase I clinical trial (SABCSAbstract #3119: Friday, December 12, 2008; 5:00 - 7:00 PM CST)

    About Gleevec

    Gleevec(R) (imatinib mesylate) tablets are indicated for the treatment of newly diagnosed adult patients with Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in the chronic phase. Follow-up is limited to 5 years. Gleevec is also indicated for patients with Ph+ CML in blast crisis (BC), accelerated phase (AP), or in the chronic phase (CP) after failure of interferon-alpha therapy.

    Fetal harm can occur when administered to a pregnant woman; therefore, women of childbearing potential should be advised to not b
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    SOURCE Novartis Pharmaceuticals Corporation
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