Navigation Links
More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies
Date:12/3/2008

nistered an oral calcium supplement of 500 mg and a multiple vitamin containing 400 IU of vitamin D daily.

Please see full Prescribing Information.

About RAD001

RAD001, an oral once-daily inhibitor of mTOR, is an investigational drug being studied in multiple tumor types. In cancer cells, RAD001 provides continuous inhibition of mTOR, a protein that acts as a central regulator of tumor cell division, cell metabolism and blood vessel growth.

The safety and efficacy profile of RAD001 has not yet been established in oncologyand there is no guarantee that RAD001 will become commercially available for oncology indications. The active ingredient in RAD001 is everolimus, which is available in different dosage strengths under the trade name Certican(R) for the prevention of organ rejection in heart and kidney transplant recipients. Certican was first approved in the EU in 2003.

RAD001 is being evaluated as a single agent or in combination with existing therapies for renal cell carcinoma, neuroendocrine tumors, lymphoma, breast, gastric, lung and other cancers, as well as tuberous sclerosis.

About LBH589 (panobinostat)

Panobinostat (LBH589), is an investigational pan-deacetylase (DAC) inhibitor which interferes with many of the pathophysiological mechanisms involved in cancer. Specifically, panobinostat causes an increased acetylation of both histone and non-histone proteins which are implicated in oncogenesis and thereby modulates their activity. In this way, panobinostat selectively induces the death of tumor cells. To date, objective clinical responses in patients with hematologic and solid malignancies have been observed with panobinostat.

Disclaimer

The foregoing release contains forward-looking statements that can be identified by terminology such as "potential," "pipeline," "to be," "t
'/>"/>

SOURCE Novartis Pharmaceuticals Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Related medicine technology :

1. CV Therapeutics Announces Eight Abstracts Accepted for Presentation at the European Society of Cardiology Congress 2007
2. Strength and Innovation of Novartis Oncology Products and Pipeline With Potential to Improve Patient Treatment Demonstrated by More Than 170 Abstracts at ASCO Annual Meeting
3. Genta Clinical Programs Featured in Multiple Abstracts at the Annual Meeting of the American Society of Clinical Oncology
4. Biodel Inc. Announces the Completion of Its Two Pivotal Trials and the Release of EASD Abstracts Containing Additional Interim Data From Its VIAject(TM) Program
5. New Data Reveal Topical Divigel(R) (estradiol gel) 0.1% Significantly Reduces Frequency and Severity of Hot Flashes
6. Study Results Reveal alli(R) Patient Satisfaction Linked to Weight Loss Achieved; Not Treatment Effects
7. A Sociolinguistic Analysis of In-Office Dialogue Reveals Psychiatrists and Parents Have Significantly Different Perceptions on ADHD and Psychiatric Comorbidities
8. New Conflict of Interest Violations Revealed at California Stem Cell Institute
9. St. Jude Gene Study Reveals Basis of Anti-Cancer Drug Resistance in Childhood Leukemia
10. Protein Tomography(TM) Reveals Molecular Mode of Action of Humax-EGFr Published in PNAS
11. Imaging Results From the ADAGIO-LIPIDS Reveal That Effects of Rimonabant on Cardiometabolic Risk Profile Include Loss of Visceral Fat and Mobilization of Liver Fat
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... CHAPEL HILL, N.C. , May 22, 2015 ... will be hosting its sixth Medical Affairs ... – 12:30PM (EDT) via a virtual roundtable to ... Outcomes Research." Best Practices, Medical Affairs ... for sharing insights about the key challenges they ...
(Date:5/22/2015)... , May 22 2015 /CNW/ - The Taskforce representing ... very appreciative of all the hard work that the Minister ... past six months. This program recognizes the needs of the ... at least $75,000 a year, tax free, with annual adjustments ... be eligible for annual payments of $100,000 based on the ...
(Date:5/22/2015)... May 22, 2015  Amgen (NASDAQ: ... commenced termination of its participation in the ... (LON:AZN, STO:AZN and NYSE: AZN ).  ... development for patients with moderate-to-severe plaque psoriasis, ... was based on events of suicidal ideation ...
Breaking Medicine Technology:Best Practices Sixth Medical Affairs Consortium Roundtable to Focus on Health Economics & Outcomes Research 2Amgen to terminate participation in co-development and commercialization of brodalumab 2Amgen to terminate participation in co-development and commercialization of brodalumab 3Amgen to terminate participation in co-development and commercialization of brodalumab 4Amgen to terminate participation in co-development and commercialization of brodalumab 5
... Nov. 3, 2011 Chembio Diagnostics, Inc. ... manufactures, markets and licenses point-of-care diagnostic tests, reported revenues and ... were $5.92 million for the quarter ended September ... to total revenues of $4.51 million for the quarter ended ...
... Endoscopy, Inc. (OTCPK: SNDY) is pleased to announce that the ... Apps, will be able to expand and improve collaboration with ... communicate efficiently.  Solos will now have the capability to communicate ... mobile device, helping the Company reduce its IT costs. ...
Cached Medicine Technology:Chembio Reports 3rd Quarter 2011 Results 2Chembio Reports 3rd Quarter 2011 Results 3Chembio Reports 3rd Quarter 2011 Results 4Chembio Reports 3rd Quarter 2011 Results 5Chembio Reports 3rd Quarter 2011 Results 6Chembio Reports 3rd Quarter 2011 Results 7Chembio Reports 3rd Quarter 2011 Results 8Chembio Reports 3rd Quarter 2011 Results 9Chembio Reports 3rd Quarter 2011 Results 10Chembio Reports 3rd Quarter 2011 Results 11Solos Endoscopy Goes Google 2Solos Endoscopy Goes Google 3
(Date:5/23/2015)... Injury lawyer Steven H. Heisler commented today on ... Maryland legislature but which has not been signed to date ... HB 449 with overwhelming bipartisan support on April 10, ... law. This bill ensures that fracking is prohibited in Maryland ... danger of fracking to our water supplies and the air ...
(Date:5/22/2015)... 2015 The American College of Traditional ... June. They will hold a webinar on the updates ... class on Classical Chinese Medicine. , Webinar – First ... Given, the Dean of Clinical Education, will lead this ... Professional Doctorate program. ACTCM is currently developing this degree ...
(Date:5/22/2015)... (PRWEB) May 22, 2015 Hundreds ... on behalf of individuals who allegedly experienced serious ... use continue to move forward in the U.S. ... a Pretrial Order dated May 4, 2015, the ... documents and electronically stored information. Among other things, ...
(Date:5/22/2015)... 2015 Combination therapy, or polytherapy, ... chronic obstructive pulmonary disorder (COPD) as the dominant ... plc as well as Germany’s Boehringer Ingelheim compete ... But will market payers, clinicians and patients be ... to completely new ones? , In spite of ...
(Date:5/22/2015)... Family, friends, students, colleagues, mentors and fellow ... LaSalle D. Leffall, on Monday, May 18, with an ... Rounds in the hospital’s Tower Auditorium. Leffall’s younger sister, ... trying to keep the secret. “I’d like to go ... he’ll know something is up,” she said. , After ...
Breaking Medicine News(10 mins):Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 2Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 3Health News:ACTCM Announces Upcoming June Events 2Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 2Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 3Health News:Court Overseeing Federal Xarelto Lawsuits Establishes Procedures Governing Preservation of Documents, Electronically Stored Information 4Health News:Chronic Obstructive Pulmonary Disorder Therapeutics Market Discussed in In-demand FirstWord Report Published at MarketPublishers.com 2Health News:Colleagues Surprise Dr. LaSalle Leffall with 85th Birthday Celebration 2
... Forest University School of Medicine and colleagues who are ... a second independent site within the HNF1B gene on ... variants that may contribute to risk of developing the ... previously discovered site in the same gene among two ...
... Tuesday 2 September 2008: , Compared to the 2003 ... the need for setting up networks of hospitals ... connected by an efficient ambulance service , the ... use of antithrombotic co-therapies with both primary PCI and fibrinolytis ...
... -- The Food and Drug Administration Modernization Act (FDAMA, ... children, has resulted in more than 130 label changes ... researchers at Duke Children,s Hospital. , Their analysis appears ... Under this and subsequent renewal of this legislation, pharmaceutical ...
... an increased risk for bipolar disorder in their offspring, ... Archives of General Psychiatry , one of the ... mood disorder involving episodes of mania and depression, according ... family history of psychotic disorders, few risk factors for ...
... of orphaned youth age 12 to 24 who head households ... report in the August issue of Archives of Pediatrics ... The combined effects of the 1994 genocide and the HIV ... in the worldan estimated 290,000 in 2005, according to background ...
... outcome months after patient went home , , MONDAY, Sept. ... the day while in rehabilitation have less functional recovery, ... expected to be published in the Sept. 1 issue ... and other predictors of recovery (e.g., mental status, hours ...
Cached Medicine News:Health News:Scientists find second site for prostate cancer gene 2Health News:Post-marketing studies finding adverse events in drugs used in children 2Health News:Post-marketing studies finding adverse events in drugs used in children 3Health News:Children of older fathers more likely to have bipolar disorder 2Health News:Depression common among Rwandan youth who head households 2Health News:Daytime Sleeping Linked to Poor Recovery in Older Patients 2