Navigation Links
More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies
Date:12/3/2008

mg/kg if rise in serum creatinine to > 33% above average of the pretreatment measurements is seen at 2 consecutive visits, and cannot be attributed to other causes. For pediatric patients, reduce dose by 10 mg/kg if serum creatinine levels rise above age-appropriate upper limit of normal at 2 consecutive visits. If there is a progressive increase in serum creatinine beyond the age-appropriate upper limit of normal, interrupt Exjade use. Once the creatinine has returned to within the normal range, therapy with Exjade may be reinitiated at a lower dose followed by gradual dose escalation, if the clinical benefit is expected to outweigh potential risks.

Intermittent proteinuria (urine protein/creatinine ratio >0.6 mg/mg) occurred in 18.6% of Exjade-treated patients, compared to 7.2% of deferoxamine-treated patients in Study 1, and monthly monitoring is recommended.

There have been post-marketing reports of cytopenias (including agranulocytosis, neutropenia and thrombocytopenia) in patients treated with Exjade. Some of these patients died. The relationship of these episodes to treatment with Exjade is uncertain. Most of these patients had pre-existing hematologic disorders that are frequently associated with bone marrow failure. In line with standard clinical management, monitor blood counts regularly. Consider interrupting treatment with Exjade in patients who develop unexplained cytopenia. Reintroduction of therapy with Exjade may be considered once the cause of the cytopenia has been elucidated.

There have been post-marketing reports of hepatic failure, some with a fatal outcome, in patients treated with Exjade. Most of these events occurred in patients greater than 55 years of age. Most reports of hepatic failure involved patients with significant comorbidities, including liver cirrhosis and multi-organ failure. Monitor liver function tests monthly during Exjade treatment and consider dose modifi
'/>"/>

SOURCE Novartis Pharmaceuticals Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Related medicine technology :

1. CV Therapeutics Announces Eight Abstracts Accepted for Presentation at the European Society of Cardiology Congress 2007
2. Strength and Innovation of Novartis Oncology Products and Pipeline With Potential to Improve Patient Treatment Demonstrated by More Than 170 Abstracts at ASCO Annual Meeting
3. Genta Clinical Programs Featured in Multiple Abstracts at the Annual Meeting of the American Society of Clinical Oncology
4. Biodel Inc. Announces the Completion of Its Two Pivotal Trials and the Release of EASD Abstracts Containing Additional Interim Data From Its VIAject(TM) Program
5. New Data Reveal Topical Divigel(R) (estradiol gel) 0.1% Significantly Reduces Frequency and Severity of Hot Flashes
6. Study Results Reveal alli(R) Patient Satisfaction Linked to Weight Loss Achieved; Not Treatment Effects
7. A Sociolinguistic Analysis of In-Office Dialogue Reveals Psychiatrists and Parents Have Significantly Different Perceptions on ADHD and Psychiatric Comorbidities
8. New Conflict of Interest Violations Revealed at California Stem Cell Institute
9. St. Jude Gene Study Reveals Basis of Anti-Cancer Drug Resistance in Childhood Leukemia
10. Protein Tomography(TM) Reveals Molecular Mode of Action of Humax-EGFr Published in PNAS
11. Imaging Results From the ADAGIO-LIPIDS Reveal That Effects of Rimonabant on Cardiometabolic Risk Profile Include Loss of Visceral Fat and Mobilization of Liver Fat
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/1/2015)... , May 01, 2015 Research and Markets ... "Asian Dermatology Devices Market by Type, by End User - ... The Asian Dermatology Devices market is estimated to grow at ... China holds a larger share in the Dermatology ... Japan . The Asian Dermatology Devices market holds a ...
(Date:5/1/2015)... At the American Association of Neurological Surgeons (AANS) Annual ... , Elekta will highlight Leksell Gamma Knife® Registry ... enormous amount of data – generated by thousands of ... advance clinical research and further optimize patient care. ... allows practitioners to store, retrieve, and analyze Gamma Knife ...
(Date:5/1/2015)... Pharmacyclics, Inc. (the "Company") (NASDAQ: PCYC ) today ... 2015, as well as general business updates. Due to ... be held. Key Highlights , Total ... to $206 million from $119 million for the quarter ... (ibrutinib) net product revenue of $247 million was ...
Breaking Medicine Technology:Asian Dermatology Devices (Treatment & Diagnostic) Market by Type, by End User - Forecast to 2019 2Asian Dermatology Devices (Treatment & Diagnostic) Market by Type, by End User - Forecast to 2019 3Elekta to showcase Leksell Gamma Knife Registry at AANS Annual Meeting 2Elekta to showcase Leksell Gamma Knife Registry at AANS Annual Meeting 3Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 2Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 3Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 4Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 5Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 6Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 7Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 8Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 9Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 10Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 11Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 12Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 13Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 14Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 15Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 16Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 17Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 18Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 19Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 20Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 21Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 22Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 23Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 24Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 25Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 26Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 27Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 28Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 29Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 30Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 31Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 32
... from cutting-edge treatment, CHARLESTON, S.C., April 30 ... Charleston was diagnosed with craniosynostosis, a,condition that leads ... causing problems with normal brain and skull growth., ... Amelia,s skull was,growing in an asymmetrical fashion, a ...
... WILMINGTON, Del., April 30 AstraZeneca (NYSE:,AZN) today ... Application,(sNDA) to the U.S. Food and Drug Administration ... (budesonide/formoterol fumarate dihydrate),Inhalation Aerosol for the treatment of ... currently approved for the long-term,maintenance treatment of asthma ...
Cached Medicine Technology:STARscanner, STARband Cranial Helmets Making a Difference in the Lives of Children 2STARscanner, STARband Cranial Helmets Making a Difference in the Lives of Children 3AstraZeneca Submits an sNDA for SYMBICORT(R) for COPD Indication 2AstraZeneca Submits an sNDA for SYMBICORT(R) for COPD Indication 3AstraZeneca Submits an sNDA for SYMBICORT(R) for COPD Indication 4AstraZeneca Submits an sNDA for SYMBICORT(R) for COPD Indication 5
(Date:5/4/2015)... May 04, 2015 Today, Cireson reveals ... Cireson Platform to strengthen core service & ... a choice to consume Microsoft System Center and Cireson ... premise , Company transitioning from a direct ... Continuous innovation with expanding new solutions for password ...
(Date:5/3/2015)... Association 2015 Meeting & Tradeshow (PRWEB) May 03, ... full-service telemedicine and mobile health services provider today ... health services for chronic disease management, in the ... remote patient monitoring of a variety of chronic ... diabetes, COPD, hypertension and other chronic illnesses. , ...
(Date:5/3/2015)... ST. LOUIS, Missouri (PRWEB) May 03, 2015 ... in international business that will directly impact your ... (EMIB), is designed for dynamic leaders in multinational ... a multinational company. In a changing global landscape, ... business negotiations and relationships. The EMIB program develops ...
(Date:5/2/2015)... one of only 30 Illinois companies to be a ... Recognition Program (SHARP) certification, Essentra Specialty Tapes ... of Labor to host this special event. The ... Occupational Safety and Health Administration’s (“OSHA”) Onsite Consultation Program ... exceed all of the necessary regulations and standards, thanks ...
(Date:5/2/2015)... 02, 2015 It’s a pattern that ... disaster strikes anywhere on this planet, cyber scammers will ... and compassion for their own personal gain. And ... Readiness Team) issued an alert titled “Nepal Earthquake ... scams citing the earthquake in Nepal. The scam emails ...
Breaking Medicine News(10 mins):Health News:Cireson Unveils New Microsoft Cloud & System Center Strategy 2Health News:Cireson Unveils New Microsoft Cloud & System Center Strategy 3Health News:Cireson Unveils New Microsoft Cloud & System Center Strategy 4Health News:vitaphone e-health solutions U.S. Announces VITA Health Services for Remote Chronic Disease Management 2Health News:vitaphone e-health solutions U.S. Announces VITA Health Services for Remote Chronic Disease Management 3Health News:The Saint Louis University's Master of International Business Is Now Enrolling For Fall 2015 2Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 2Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 3Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 2Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 3Health News:Cyber Aftershocks from Nepal’s Earthquake Can Cripple Businesses Right Here at Home 4
... men with low-risk prostate cancer than the common method ... a research// team at the University of Michigan in ... conducted by lead researcher Dr. John T. Wei and ... the National Cancer Institute. Their studies have revealed that ...
... his electorate of Warringah this morning, AMA President, Dr ... already shrinking GP workforce will retire over the next ... week's Medical Journal of Australia confirming that general practice ... graduates, the challenge is how to support those staying ...
... find the response time of ambulance services for emergency calls ... details for how they responded to the most serious life-threatening ... target saying 75 per cent of such 'Category A' calls ... by the Information Center for Health and Social Care from ...
... grow rapidly unless eight countries in the region, especially ... measures, according to a new World Bank report. ... in South Asia, with the epidemic increasingly driven by ... said the report presented at the 16th International AIDS ...
... children from Isiolo District in Northern Kenya have died at ... a tropical infection caused by protozoa// of the genus Leishmania, ... ,It spreads to people through the bite of the sand ... in the victim’s body, invading the immune system. However, not ...
... a good alternative for identifying risks for kidney disease, cardiovascular ... by a researcher at the San Francisco VA Medical Center, ... is incapable of picking up chronic health risks among the ... others at risk for kidney disease, this is an important ...
Cached Medicine News:Health News:Watchful Waiting Effective for Low Risk Prostate Cancer 2Health News:Keep Australia's GP Workforce Numbers Healthy, AMA Urges 2Health News:Incorrect Recording Of Response Time By Six Ambulance Trusts 2Health News:India Urged to Take Stringent Measures to Combat AIDS 2Health News:India Urged to Take Stringent Measures to Combat AIDS 3Health News:Cystatin C Test- A Reliable Test to Detect Chronic Health Risks 2Health News:Cystatin C Test- A Reliable Test to Detect Chronic Health Risks 3
... Maximum Xtra, and Maximum ACT introducers ... and specialty hemostasis introducers in the ... premier hemostasis introducers for use in ... angiography, angioplasty, stenting, atherectomy, temporary pacing, ...
... provide outstanding insertion performance, with ... high kink resistance and minimal ... sheath cannula provides optimal strength ... an extra strong dilator to ...
Bx VELOCITY Coronary Stent with HEPACOAT...
A steerable diagnostic catheter with optimal maneuverability...
Medicine Products: