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Monogram Provides Update on Trofile(TM) Co-Receptor Tropism Assay
Date:9/18/2007

Pfizer reports long-term safety and efficacy data for HIV drug

Selzentry(TM) (Maraviroc)

SOUTH SAN FRANCISCO, Calif., Sept. 18 /PRNewswire-FirstCall/ -- Monogram Biosciences, Inc. (Nasdaq: MGRM) announced today that its collaborator Pfizer, Inc. (NYSE: PFE) has separately announced data that reinforces long-term safety and efficacy of Pfizer's oral CCR5-antagonist, Selzentry (Maraviroc), which was recently approved by the FDA and is now available throughout the U.S. Monogram's co-receptor tropism assay, Trofile(TM), was used for patient selection for Selzentry's clinical development program, and is currently being marketed by Monogram's 50-strong sales and marketing organization. Recently, Monogram announced that the contractor that administers Medicare programs in California has established coding procedures for the company's Trofile Assay, indicating Medicare coverage of Trofile throughout the U.S.

At the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) meeting in Chicago, Pfizer presented data from a planned 48-week analysis of its clinical studies of Selzentry in treatment-experienced patients. This analysis confirms the previous 24-week data on which the FDA approval of Selzentry was based. The 48-week analysis showed:

-- that nearly three times as many patients receiving Selzentry in

addition to an optimized background regimen achieved undetectable

levels of virus compared with thos
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SOURCE Monogram Biosciences, Inc.
Copyright©2007 PR Newswire.
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