Navigation Links
Monogram Biosciences Provides Progenics Pharmaceuticals with HIV Assays for Use in Clinical Trials
Date:4/1/2008

Trofile to be used to screen patients for clinical program of monoclonal

antibody to CCR5

SOUTH SAN FRANCISCO, Calif., April 1, 2008 /PRNewswire-FirstCall/ -- Monogram Biosciences, Inc., (Nasdaq: MGRM) announced today that it had entered into an agreement with Progenics Pharmaceuticals, Inc. (Nasdaq: PGNX) to provide resistance and tropism testing for Progenics' clinical development program of PRO 140, an investigational CCR5 monoclonal antibody being studied for the treatment of HIV. In its ongoing phase 2 studies, Progenics is using Monogram's Trofile(TM) tropism test to screen and monitor HIV infected individuals whose virus uses the CCR5 receptor as a portal of entry to healthy cells. Progenics is also using Monogram's PhenoSense GT(TM) assay to measure viral resistance to drugs from other HIV-1 treatment classes.

"We are pleased to play such an important role in the development of this promising new HIV therapy," said Chris Petropoulos, Monogram's Chief Scientific Officer. "Monogram continues to help pave the path for many of the most highly anticipated new HIV drugs in development."

Trofile is a patient selection co-receptor tropism assay that determines whether a patient is infected with a strain of HIV that uses the CCR5 co- receptor, the CXCR4 co-receptor, or a combination of CCR5 and CXCR4 to enter cells. Trofile is the only clinically validated tropism assay and has been used to select patients in all phase 2 and phase 3 studies of CCR5 antagonists to date.

About PRO 140

Progenics announced the start of the phase 2 program for PRO 140 in January 2008. PRO 140 is a novel monoclonal antibody that binds CCR5 and is designed to prevent HIV from entering immune system
'/>"/>

SOURCE Monogram Biosciences, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Monogram Announces Posters to be Presented at the 30th San Antonio Breast Cancer Symposium
2. Monogram Provides Update on Trofile(TM) Co-Receptor Tropism Assay
3. Medicare Contractor Establishes Reimbursement Coding Guidance for Monograms Trofile Assay
4. Sangamo BioSciences and Sigma-Aldrich Announce Publication of Study Demonstrating Zinc Finger Technology for Rapid Generation of Knock-Out Cell Lines
5. Novel PCT Method Unveiled by Pressure BioSciences, Inc. and Collaborators at the Harvard School of Public Health
6. Ardea Biosciences Reports Positive Phase 2a Results for Lead HIV Candidate, RDEA806, Demonstrating up to 2.0 Log Reduction in Plasma Viral Load
7. Ardea Biosciences Presents Preclinical Data Demonstrating Favorable Resistance Profiles for Non-Nucleoside Reverse Transcriptase Inhibitors for the Treatment of Human Immunodeficiency Virus
8. Sangamo BioSciences Reports 2007 Fourth Quarter and Year-End Financial Results
9. Neurocrine Biosciences Reports Fourth Quarter and Year-End 2007 Results
10. CeloNova BioSciences Introduces a New Class of Coronary Stent: The CATANIA(TM) Coronary Stent System with NanoThin Polyzene(R)-F
11. CeloNova BioSciences Announces Positive Results from European Study of Embozene(TM) Microspheres for Treatment of Uterine Fibroids
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2014)... PLEASANTON, Calif. , July 21, 2014 ... leader in device-based mechanical circulatory support therapies to save, ... will report its operating results for the second quarter ... The company will hold a conference call to ... all interested parties, at 1:30 p.m., Pacific Daylight Time ...
(Date:7/21/2014)... , July 21, 2014  EHE International, the ... with a nationwide physician network, today announced that Dignity ... Vegas, NV has been named an EHE-certified ... Las Vegas region now have ... proactively maintain their health. "EHE is ...
(Date:7/21/2014)... 21, 2014 /PRNewswire-iReach/ -- Top Brooklyn Pediatrician ... to an article, which suggests that caffeine may be ... http://photos.prnewswire.com/prnh/20140718/128611 A few decades ... to children, but now it happens rather frequently, according ... study, published in the journal Pediatrics, discussed a new ...
Breaking Medicine Technology:Thoratec Schedules Second Quarter Conference Call, Webcast 2EHE International Certifies Dignity Health Medical Group Nevada, LLC as Its Newest Partner 2Dr. Michael Gabriel a Brooklyn Pediatrician Comments on an Article, Which Suggests Caffeine May Be Dangerous for Children 2
... options and research directions , , WASHINGTON, June ... therapeutic option for many patients with interstitial cystitis (IC). IC ... 8 million women and 1.5 million men in the United ... noticed a correlation between allergies and IC. Recently, a urologist ...
... Families of Spinal Muscular Atrophy has just released details ... funded therapeutic pipeline. , , Families of SMA ... Quinazolines to boost gene expression; 2) Tetracyclines at Paratek ... replacement program at California Stem Cell and UCI. ...
Cached Medicine Technology:Urologist and Allergist Explore Link Between Allergies and Interstitial Cystitis 2Urologist and Allergist Explore Link Between Allergies and Interstitial Cystitis 3Urologist and Allergist Explore Link Between Allergies and Interstitial Cystitis 4Families of Spinal Muscular Atrophy Announces Latest Developments on Three SMA Drug Discovery Programs 2Families of Spinal Muscular Atrophy Announces Latest Developments on Three SMA Drug Discovery Programs 3
(Date:7/22/2014)... The Middle East Drilling fluid and Completion fluid ... fluid market in Middle East with analysis and forecast of ... East is estimated to grow from around $560 million in ... 5.7%, for the given period. , Browse through the TOC ... report, to get an idea of the in-depth analysis provided. ...
(Date:7/22/2014)... 2014 Dimension One Spas’ retailers across ... on all models during the “Let’s Take This Outside” ... http://www.d1spas.com/financing for more information and to apply. ... Spas offers a wide variety of outdoor hot tubs ... waterfalls, music, customizable massage, and personal controls. ...
(Date:7/22/2014)... July 22, 2014 Marine threats ... environmental destruction, sea-borne illegal immigration, and international criminal ... regulated and standard maritime security systems. Due to ... has crossed $13.93 billion in 2014 and is ... global maritime security market is expected to grow ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 Location-based ... ubiquitous applications on location-based data. The retail and ... in order to reduce transportation costs. Due to ... market has reached $8.12 billion in 2014, and ... at a calculated CAGR of 37.50% during this ...
(Date:7/22/2014)... HealthDay Reporter TUESDAY, July ... day help predict survival and the course of the disease ... Gehrig,s disease, Italian researchers report. , , The components in ... is progressing are called albumin and creatinine. These components are ... the U.S. National Library of Medicine. But now it ...
Breaking Medicine News(10 mins):Health News:Middle East Drilling Fluid & Completion Fluid Market is Expected to Reach $740 Million in 2018 - New Report by MicroMarket Monitor 2Health News:Middle East Drilling Fluid & Completion Fluid Market is Expected to Reach $740 Million in 2018 - New Report by MicroMarket Monitor 3Health News:Middle East Drilling Fluid & Completion Fluid Market is Expected to Reach $740 Million in 2018 - New Report by MicroMarket Monitor 4Health News:Middle East Drilling Fluid & Completion Fluid Market is Expected to Reach $740 Million in 2018 - New Report by MicroMarket Monitor 5Health News:Middle East Drilling Fluid & Completion Fluid Market is Expected to Reach $740 Million in 2018 - New Report by MicroMarket Monitor 6Health News:North America Maritime Security Market is Expected to Reach $4.76 billion in 2019 - New Report by MicroMarket Monitor 2Health News:North America Maritime Security Market is Expected to Reach $4.76 billion in 2019 - New Report by MicroMarket Monitor 3Health News:North America Maritime Security Market is Expected to Reach $4.76 billion in 2019 - New Report by MicroMarket Monitor 4Health News:North America Location Based Services (LBS) Market is Expected to Reach $13.10 Billion in 2019 - New Report by MicroMarket Monitor 2Health News:North America Location Based Services (LBS) Market is Expected to Reach $13.10 Billion in 2019 - New Report by MicroMarket Monitor 3Health News:North America Location Based Services (LBS) Market is Expected to Reach $13.10 Billion in 2019 - New Report by MicroMarket Monitor 4Health News:North America Location Based Services (LBS) Market is Expected to Reach $13.10 Billion in 2019 - New Report by MicroMarket Monitor 5Health News:Blood Test Might Help Predict Survival With Lou Gehrig's Disease 2Health News:Blood Test Might Help Predict Survival With Lou Gehrig's Disease 3
... Jude scientist honored , , MEMPHIS, Tenn., June 16 ... in the Pathology Department at St. Jude Children,s Research Hospital, ... Sciences. , , Selected by The Pew Charitable Trusts ... scientists, Mullighan will receive a $240,000 award over four years ...
... , NIXA, Mo., June 16 The National Autism Association ... charge to qualifying couples who have a child with autism. ... divorce within the autism community, the NAA,s Family First Program ... need of marriage counseling. Now the organization is providing tools ...
... -- Duke University engineers have taken a first ... by combining chemotherapy with heat administered from the end ... it should be technically possible to treat brain tumors ... of surgery, systemic chemotherapy or radiation. The bioengineers ...
... and the Association of Medicine and the Person are collaborating ... . The peer-reviewed, international journal is aimed at medical ... field of ethics and quality of life. The first ... The Journal of Medicine and the Person ...
... of organizations representing healthcare stakeholders throughout Greater Boston ... Foundation (RWJF) to participate in a planning grant ... Quality (AF4Q) initiative. AF4Q is the Foundation,s signature ... in targeted communities, reduce racial and ethnic disparities, ...
... ... ... , , ,Who: ,Dr. Jeffrey Sturchio, Chairman, Corporate Council on Africa, ... Office of the U.S. Global AIDS Coordinator, U.S. Department of State ,Dr. Kate Tulenko, ...
Cached Medicine News:Health News:St. Jude Scientist Named Pew Scholar 2Health News:St. Jude Scientist Named Pew Scholar 3Health News:National Autism Association's Family First Program Now Providing Free Tools to Help Combat Autism Divorce Rates 2Health News:Potential for noninvasive brain tumor treatment 2Health News:Springer to publish Journal of Medicine and the Person 2Health News:Greater Boston unites to transform health care 2Health News:Building Healthcare Leadership in Africa: A Call to Action 2
... The AlphaPette Pipettor is the #1 ... Offers accuracy, comfort, and reliability. Continuously ... volume readout sub-micrometer. Easy interchangeable ejector ... tiny hands. Adjustable rapid pipet tip ...
... The Finnpipette Digital offers improved ergonomics ... rounded handle, modified grippy finger rest ... operator comfort and efficiency. Finnpipette Digitals ... power-boosted gearing mechanism (pat. pend.) and ...
... is the #1 Pipettor for sub-microliter ... and reliability. Continuously adjustable. Features lPLUS, ... Easy interchangeable ejector buttons to fit ... rapid pipet tip ejector with three ...
... Recommended for aqueous samples of moderate viscosity and density. Proven ergonomic design ... Volume Range(ul) ... 0.8~1.5 Imprecision(%) ... (ul) ...
Medicine Products: