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MonoSol Rx, LLC Announces Suboxone Sublingual Film Achieves 25% Share of Total U.S. Suboxone Market Volume at Year-End 2010
Date:2/22/2011

WARREN, N.J., Feb. 22, 2011 /PRNewswire/ -- MonoSol Rx, LLC ("MonoSol Rx"), the developer of PharmFilm® drug delivery technology, today announced that Reckitt Benckiser Pharmaceuticals Inc., a wholly-owned subsidiary of Reckitt Benckiser Group plc ("the Group") (LSE: RB), provided an update on U.S. market adoption of Suboxone® (buprenorphine HCl/naloxone HCl dihydrate) sublingual film for the treatment of opioid dependence during its announcement of full-year 2010 financial results.

Full-year 2010 net revenue for the Group's Subutex and Suboxone prescription drug business grew 24% to 737 million pounds Sterling. At the end of 2010, the market volume share for Suboxone sublingual film was 25%, and at this level would represent approximately 23% of the total U.S. net revenue for Reckitt Benckiser Pharmaceuticals Inc. (approximately 138m pounds on an annualized basis).

Suboxone sublingual film was developed through an exclusive agreement with Reckitt Benckiser Pharmaceuticals and MonoSol Rx, utilizing MonoSol Rx's proprietary PharmFilm® technology, to deliver a convenient, quick-dissolving better tasting therapeutic dose of buprenorphine, a partial opioid agonist, and naloxone, an opioid antagonist. The drugs rapidly absorb under the tongue to ensure efficacy and compliance.

A. Mark Schobel, President and CEO of MonoSol Rx, stated, "The patients and treating physicians acceptance of Suboxone sublingual film demonstrates not only the advantages of our dosage form but also the value we create for our partners as they look to protect their product franchises following exclusivity losses.  We are very happy with the market penetration of the new Suboxone sublingual films and are looking forward to continued success in 2011 and beyond."

On October 8, 2009, Suboxone lost the U.S. exclusivity afforded by its orphan drug status. In September 2010, Reckitt-Benckiser Pharmaceuticals introduced Suboxone sublingual film, a
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SOURCE MonoSol Rx, LLC
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