Navigation Links
Moffitt Cancer Center and CvergenX, Inc. Sign Licensing Agreement
Date:7/27/2010

TAMPA, Fla., July 27 /PRNewswire/ -- Moffitt Cancer Center and CvergenX, Inc., announced today that they have entered into a licensing agreement under which CvergenX has acquired the exclusive worldwide rights to a technology platform that individualizes radiation therapy, InterveneXRT™. Researchers at Moffitt have used gene expression analysis and systems biology to create a radio-sensitivity classification index for individual tumors.  

"While genomic analysis has been applied in the development of diagnostic tools to guide chemotherapy use, this is the first time that the field has expanded to radiation therapy," said Dr. Javier F. Torres-Roca, the radiation oncologist who co-founded CvergenX with Steven A. Eschrich, Ph.D., both Moffitt faculty members.  "Radiation therapy has undergone vast changes with significant improvements in imaging and engineering that better direct the treatment, but this level of analysis will truly individualize each treatment, arming oncologists with answers as to when to radiate and how much to radiate — information that has been unavailable until now."

Radiation therapy is prescribed for more than 60 percent of all cancer patients, more than any single chemotherapy agent.  

"There has been an unmet need to develop biomarkers that predict response to radiation therapy," said Jarett Rieger, director of the Office of Technology Management and Commercialization at Moffitt.  "The cutting-edge and innovative research by Drs. Torres-Roca and Eschrich has led to this incredible breakthrough in the field of personalized medicine.  Our office is delighted that CvergenX, a Moffitt faculty startup based in Tampa Bay, will move this biomarker discovery from the laboratory to the clinic to improve patient care."  

Based upon seven years of research and more than $2 million in research primarily funded through the National Cancer Institute, the testing platform is undergoing clinical studies for further validation and optimization of its methods. Under the license agreement, CvergenX has agreed to pay Moffitt when various commercialization milestones are reached, as well as royalty payments on the sales of testing services and licensed products.

"The license agreement is one of the key milestones established for the company in 2010," said Mary Del Brady, chairman and CEO of CvergenX. "With the intellectual property fully protected, we are poised to proceed with the commercialization of InterveneXRT, including studies across multiple disease sites and, later, the opening of an independent advanced diagnostics laboratory.  We believe that the individualization of radiation therapy is an important component of personalized cancer treatment."  

About Moffitt Cancer Center

Located in Tampa, Florida, Moffitt Cancer Center  is an NCI Comprehensive Cancer Center - a designation that recognizes Moffitt's excellence in research and contributions to clinical trials, prevention and cancer control. Moffitt currently has 15 affiliates in Florida, one in Georgia and two in Puerto Rico. Additionally, Moffitt is a member of the National Comprehensive Cancer Network, a prestigious alliance of the country's leading cancer centers, and is listed in U.S. News & World Report as one of "America's Best Hospitals" for cancer. Moffitt's sole mission is to contribute to the prevention and cure of cancer.

About CvergenX, Inc.

CvergenX is an early stage advanced diagnostic services company that was founded to provide personalized medicine tools for the field of radiation oncology.  The Company's Intervene XRT testing platform applies genomic analysis to predict a tumor's response to radiation and to assist the oncologist in determining the optimal level of radiation dosing.  CvergenX joins a growing group of personalized medicine companies that are applying genomics-basis analysis to clinical practice to enable a more personalized and accurate approach to patient care.


'/>"/>
SOURCE Moffitt Cancer Center
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. CMC, Moffitt Partner to Study Cancer
2. Moffitt Cancer Center Signs Licensing Agreement with Frantz BioMarkers, LLC
3. Philips SmartArc Solution Helps Moffitt Cancer Center Reduce Radiation Treatment Time
4. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
5. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
6. Indevus Receives Approvable Letter From FDA for VALSTAR(R) for Bladder Cancer Therapy
7. EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
8. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
9. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
10. Novel Technology Breaks Through Cancer Pain
11. CEL-SCI Secures Manufacturing Facility for Multikine Cancer Drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/2/2017)... PHILADELPHIA , Oct. 2, 2017 Halo Labs announces ... particle analysis system called the HORIZON at MIBio 2017 in ... analyzes subvisible and visible particulate matter in biopharmaceutical samples with unprecedented ... use of the novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
(Date:9/27/2017)... Sept. 27, 2017  Commended for their devotion to personalized ... Ranked as number one in the South Florida Business Journal,s ... Inc. 5000 yearly list, the national specialty pharmacy has found ... Bardisa will soon be honored by SFBJ as the ... Set to receive his award in October, Bardisa ...
(Date:9/23/2017)... Janssen Biotech, Inc. (Janssen) announced today that ... U.S. Food and Drug Administration (FDA) for the Biologics ... treatment of moderately to severely active rheumatoid arthritis (RA). ... needed to further evaluate the safety of sirukumab in ... "We are disappointed ...
Breaking Medicine Technology:
(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids ... sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited ... all ages; it is a non-competitive, non-timed event, which is all about having fun ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the ... save lost souls in the Philippines. “The Journey: From the Mountains to the Mission ... of the Bible. She has taught all ages and currently teaches a class of ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the ... today its plans to open a flagship location in Covington, LA at 401 N. ... To Go store next to Office Depot in the Holiday Square shopping center. Its ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a nationally recognized ... have expanded their existing home health joint venture through an agreement, effective October ... a joint venture home health company with Asante, delivering clinically integrated care, for ...
(Date:10/12/2017)... Washington, D.C. (PRWEB) , ... October 12, 2017 , ... ... of their peers in Washington, D.C., for the 49th Congress of the International ... Ph.D ., Vice President of the Center for Cancer and Blood Disorders ...
Breaking Medicine News(10 mins):