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Minimally Invasive Heart Valve Therapy Improves Heart Function, Quality of Life for Mitral Regurgitation Patients
Date:3/14/2010

ad to heart failure, stroke, heart attack or death.  The MitraClip is designed to help these patients on a case-by-case basis, and is currently under review by the FDA.

Patients participating in the EVEREST II trial experienced improvements in heart function, quality of life and the ability to engage in normal physical activity.  "[Before the procedure] I had a hard time walking up the stairs. I would have to stop several times and sometimes sit down to catch my breath," said Beyna, an EVEREST II trial participant and NorthShore patient.  "Now it's different. I don't get out of breath and I can do the things I couldn't do before."

In Phase I of the trial, started in 2003, 107 patients had their mitral valves repaired with the MitraClip, a 4 mm-wide, polyester-covered device developed by Abbott Vascular, Inc. Under general anesthesia, the clip (or sometimes two) is inserted via catheter through an artery in the groin, threaded up to the heart and clamped to the mitral valve's two edges to hold them together. The heart beats normally during the procedure, and therefore does not require a heart-lung bypass machine.

The results of Phase II, announced today, are very promising. A one-year follow-up showed that only 9.6 percent of the 279 MitraClip patients had safety issues associated with the procedure vs. 57 percent of open-heart
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SOURCE NorthShore University HealthSystem
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