MicuRx Pharmaceuticals Files Investigational New Drug Application... ( MRX-I is a next-generation oral oxazo...)

MicuRx Pharmaceuticals Files Investigational New Drug Application for MRX-I

Date:3/15/2010

MRX-I is a next-generation oral oxazolidinone antibiotic for treating methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) infections. Extensive animal studies have demonstrated that MRX-I cures infections due to Gram-positive bacteria including MRSA and VRE effectively. In addition, preclinical toxicology studies have shown that MRX-I is safe, and MicuRx anticipates a superior therapeutic window for this compound.

Multi-Drug Resistance: A Growing Global Public Health Crisis

Modern antibiotics have substantially reduced the threat posed by infectious diseases and contributed to a dramatic drop in mortality rates over the past 40 years. However, pathogenic bacteria resistant to current therapies have evolved over the years and become ubiquitous. The World Health Organization, Centers for Disease Control and the Infectious Disease Society of America have identified multi-drug resistant bacteria as a major public health threat today and into the future. In 2008, more than 65,000 people died of drug-resistant bacteria in the United States. In certain regions, the incidence of drug-resistant MRSA increased almost 70% over the last three years alone. MicuRx's compounds directly address the escalating problem of multi-drug resistant bacteria, with the potential to be used both in hospital and community-based settings.

SOURCE MicuRx Pharmaceuticals, Inc.
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