Navigation Links
Microtest Laboratories Announces New Fast-Track Toxicity Testing for Medical Devices Using Zebrafish Embryos
Date:7/6/2011

AGAWAM, Mass. July 6, 2011 /PRNewswire/ -- Microtest Laboratories has announced a new fast-track test to screen plastics and polymers in medical devices for toxicity using Zebrafish embryos (Danio rerio), a technique already widely utilized in drug development studies.

"Testing has revealed that Zebrafish embryos are highly susceptible to toxins. In fact, Zebrafish labs are ubiquitous in most universities and research hospitals," said Steven Richter, Ph.D., president and scientific director of Microtest Laboratories, and former U.S. Food & Drug Administration (FDA) official.

"We've confirmed the application of Zebrafish embryos in the toxicity testing of materials used in medical devices," Dr. Richter said. "With our in-vitro test, manufacturers and bio materials researchers can screen thousands of polymers in less than a week — yielding significant economic savings in both the time and expense of medical device testing."

In its research, Microtest Laboratories found that the current "gold standard" USP Cytotoxicity Assay, which utilizes live mouse fibroblasts (L929) cells in culture, failed to detect the toxicity of a BPA extract during testing — while Microtest's new Zebrafish embryo screen succeeded.

BPA (bis-phenol A) is a suspected toxic polymer assumed as having both carcinogenic and teratogenic effects on humans. The U.S. Environmental Protection Agency (EPA) has indicated that BPA will be slated for screening soon.

"Microtest's new Zebrafish embryo assay has better sensitivity and generates more scientific data than the small animal tests currently recommended by the FDA," Dr. Richter said.

"The use of Zebrafish embryos will reduce or eliminate the current animal testing required for all medical devices testing. This important vertebrate model has demonstrated similarities to mammalian models and humans in toxicity testing," he noted.

Microtest Laboratories' new Zebrafish embryo assay for the toxicity testing of medical devices is immediately available. For more information, visit http://www.microtestlabs.com/zebrafish-embryos-testing or call 1-413-786-1680 or toll-free 1-800-631-1680

About Microtest Laboratories

Microtest Laboratories is a leader in medical device testing and related services for the medical device, pharmaceutical, and biotechnology industries. Based in Agawam, Massachusetts, U.S.A., the company provides expertise and flexible processes that enhance product safety and security, accelerate time to market, and minimize supply chain disruption. For more information, visit http://www.microtestlabs.com or call 1-413-786-1680 or toll-free 1-800-631-1680. Follow Microtest Laboratories on Twitter @MicrotestLabs at http://twitter.com/MicrotestLabs.

Download high resolution image from: http://www.microtestlabs.com/photos

Available Topic Expert(s): For information on the listed expert(s), click appropriate link.

Steve Richter, Ph.D.
https://profnet.prnewswire.com/Subscriber/ExpertProfile.aspx?ei=42622


'/>"/>
SOURCE Microtest Laboratories
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Columbia Laboratories NDA for PROCHIEVE® Vaginal Progesterone Gel Accepted for Filing by FDA
2. Vinomis Laboratories Launches Vindurance Challenge to Substantiate Claims of Enhanced Physical Endurance with Use of Resveratrol and Quercetin
3. Millennium Laboratories Announces New General Counsel Martin Price and Chief Compliance Officer Janna Sipes
4. Signal Genetics Announces Commercialization Partnership with NeoGenomics Laboratories for Multiple Myeloma Gene Expression Test
5. MO BIO Laboratories, Inc. Launches the PowerWater® Sterivex™ DNA Isolation Kit
6. Millennium Laboratories Founder and CEO James Slattery Named Ernst & Young Entrepreneur of the Year® San Diego Finalist
7. BD Launches BD MAX™ System in U.S. to Empower Laboratories and Clinicians to Respond to Emerging Diseases
8. BD Launches BD MAX™ Open System in Europe and Reveals Strategy to Build Broad Menu of Assays that Provide Timely, Accurate Information to Laboratories and Clinicians
9. Millennium Laboratories Launches New Educational Webinar Series for Pain Management Physicians
10. Pharmatek Laboratories Adds Spray Drying to Drug Development Services
11. Millennium Laboratories Founder and CEO James Slattery Named Ernst & Young Entrepreneur Of The Year® 2011 Award Semifinalist in San Diego
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... Bill is an internationally experienced medical device industry executive who ... global medical device companies, including Smith & Nephew, Angiodynamics, Orthovita and ... and building successful businesses in the sector and has worked in ... North America . ... Educated at the University of Edinburgh (Dental Surgery), ...
(Date:1/16/2017)... Calif. , Jan. 16, 2017  Rigel Pharmaceuticals ... January 3, 2017 and January 16, 2017 the Compensation ... of inducement stock options to purchase an aggregate of ... These awards were granted pursuant to the Rigel Pharmaceuticals, ... to the new employees entering into employment with Rigel, ...
(Date:1/15/2017)... January 16, 2017 Der Vorstand ... für die Regeneration des menschlichen Gewebes, gibt die Ernennung ... sofortiger Wirkung bekannt. ... Bill Allan ist ... bekleidete eine Reihe von Geschäftsführer- und anderen Führungspositionen bei ...
Breaking Medicine Technology:
(Date:1/16/2017)... WA (PRWEB) , ... January 16, 2017 , ... NexTec ... 2016, a group of 100 organizations honored for their accomplishments in the field of ... such growth, industry leadership and recognition, and innovation. Selection is not based on revenue ...
(Date:1/15/2017)... ... January 15, 2017 , ... Accreditation Commission ... accreditation for its specialty care services. Albertsons Companies is the largest national ... service for pharmacy patients. , Accreditation by ACHC reflects Albertsons Companies’ dedication and ...
(Date:1/15/2017)... ... 15, 2017 , ... The Gravity Vault Indoor Rock Climbing Gym is excited ... up on the 14,000+ square foot climbing gym, the owners anticipate to open sometime ... New Jersey and two in New York. With this being its first location in ...
(Date:1/14/2017)... ... 14, 2017 , ... AgileMinder develops innovative products and services that bring "Care, ... available on Apple as a fun, free emoji sticker pack for iMessage. Use the ... ten color coded values on The Emoji Scale. , On Apple: "The Emoji ...
(Date:1/13/2017)... ... January 13, 2017 , ... A January 10 ... procedures for 2017 according to the publication, with an emphasis on some new techniques ... M.D., F.I.C.S., F.A.C.S., who is known more casually to his patients and colleagues as ...
Breaking Medicine News(10 mins):