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Micromet Presents Update on BiTE Antibody Pipeline and Reviews Key AACR Presentations at R&D Day
Date:4/24/2009

tations in KRAS and BRAF oncogenes do not respond to treatment with Erbitux or Vectibix. These patients make up more than 40% of colorectal cancer patients.

"Micromet has developed one of the industry's most extensive and exciting antibody pipelines. Our BiTE antibody platform continues to gain validation in the clinic leading to the planned initiation of a pivotal trial for ALL next year," said Micromet President and CEO Christian Itin. "Micromet continues to advance pre-clinical and clinical programs independently and with its partners Bayer Schering, Nycomed, Merck Serono and MedImmune."

An archive of the event's presentations is available at www.micromet-inc.com.

About Micromet

Micromet, Inc. (www.micromet-inc.com) is a biopharmaceutical company with offices in Bethesda, MD and Munich, Germany. The Company is focused on developing novel, proprietary antibodies for the treatment of cancer, inflammation and autoimmune diseases. The Company's novel antibody technology is based on its proprietary BiTE(R) antibody platform, representing a new class of antibodies that specifically activate T cells from the patient's own immune system to eliminate cancer cells or other disease related cells. Four of the Company's antibodies are currently in clinical trials, with the remainder of its product pipeline in preclinical development. The Company's lead program is a BiTE antibody known as blinatumomab, or MT103. It is in a phase 2 clinical trial for the treatment of patients with acute lymphoblastic leukemia and a phase 1 clinical trial for the treatment of patients with non-Hodgkin's lymphoma. Micromet's second BiTE antibody in clinical development is MT110, which targets the epithelial cell adhesion molecule (EpCAM). The Company owns all rights to MT110
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Related medicine technology :

1. Micromet Presents Preclinical Data Showing Activity of Erbitux and Vectibix Based BiTE Antibodies against KRAS- and BRAF-mutated Human Colorectal Cancer Cells
2. Micromet Receives Milestone Payment for Filing of the First Clinical Trial Application for MT203
3. Micromet Has Started a New Phase 2 Trial with Adecatumumab in Colorectal Cancer Patients
4. Micromet Key Events for 2009
5. Micromet Expands Committed Equity Financing Facility to $75 Million
6. Micromet Presents Data at the 23rd Annual Meeting of the International Society for Biological Therapy of Cancer on the Activity of Human Antibody Adecatumumab against KRAS-mutated Colon Cancer Cells
7. Micromet Presents Data at ESMO 2008 on Anti-EpCAM Antibody Adecatumumab (MT201) in Combination with Chemotherapy
8. Micromet, Inc. to Host Webcast and Conference Call to Discuss Blinatumomab Data Published in SCIENCE
9. Micromet, Inc. to Host Conference Call and Webcast to Discuss Second Quarter 2008 Financial Results
10. Micromet and Nycomed Begin Formal Preclinical Safety Studies for Antibody MT203 for Inflammatory and Autoimmune Diseases
11. Micromet and MedImmune Commence Treatment in Phase 2 Trial of BiTE Antibody Blinatumomab (MT103/MEDI-538) in Patients with Acute Lymphoblastic Leukemia
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