Navigation Links
Micromet Highlights Clinical Plans and Regulatory Strategy for Lead Product Candidate Blinatumomab at its Annual R&D Day
Date:2/10/2010

BETHESDA, Md., Feb. 10 /PRNewswire-FirstCall/ -- At its annual investor R&D Day today, Micromet, Inc. (Nasdaq: MITI) outlined the design of a registration study for the Company's lead product candidate blinatumomab in acute lymphocytic leukemia (ALL), highlighted clinical data demonstrating the breadth of blinatumomab's activity in B-cell non-Hodgkin's lymphomas and announced plans to expand clinical development of blinatumomab in the U.S.

"We are very pleased with the strong support received from the medical community for the planned pivotal study in adult ALL," said Christian Itin, Ph.D., Micromet's President and Chief Executive Officer. "Based on our discussions with the EMEA on the study design, we plan to initiate patient enrollment in the EU in mid-2010."  

Blinatumomab Development Program Highlights

Micromet provided additional details today on its plans to expand development of blinatumomab in leukemia:

  • EU pivotal study of blinatumomab in MRD-positive adult ALL – The Company plans to initiate a pivotal, single-arm study that will seek to enroll approximately 130 adult patients with MRD-positive ALL. Patients will receive up to four 4-week treatment cycles of blinatumomab at a dose of 15 micrograms/m2/day.  Key endpoints of the study include molecular complete response (MRD negativity) and relapse-free survival rate.  The Company currently anticipates enrolling patients in both the EU and US.  The Company plans to discuss its registration strategy for blinatumomab in the U.S. with the FDA later this year.

  • Development of blin
    '/>"/>

SOURCE Micromet, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Final Data from Phase 2 Study Confirm High Response Rate of Micromets Blinatumomab in Patients with Acute Lymphoblastic Leukemia
2. Bayer Schering Exercises Option to Develop Solid Tumor BiTE Antibody with Micromet
3. Micromet to Present at The 8th Annual BIO Investor Forum Conference on October 29, 2009
4. Micromets Blinatumomab Achieves Primary Endpoint in Phase 2 Study with Acute Lymphoblastic Leukemia Patients
5. Micromet Presents Update on Blinatumomabs Response Rate and Duration in a Phase 1 Study in Non-Hodgkins Lymphoma Patients
6. Micromet Presents Update on BiTE Antibody Pipeline and Reviews Key AACR Presentations at R&D Day
7. Micromet Presents Preclinical Data Showing Activity of Erbitux and Vectibix Based BiTE Antibodies against KRAS- and BRAF-mutated Human Colorectal Cancer Cells
8. Micromet Receives Milestone Payment for Filing of the First Clinical Trial Application for MT203
9. Micromet Has Started a New Phase 2 Trial with Adecatumumab in Colorectal Cancer Patients
10. Micromet Key Events for 2009
11. Micromet Expands Committed Equity Financing Facility to $75 Million
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Jan. 22, 2015 /PRNewswire/ - Pivotal Therapeutics Inc. (OTCQX:PVTTF; CSE:PVO), ("Pivotal" ... on Omega-3 therapies for cardiovascular disease and overall health is ... accomplishments in 2014 and its outlook for 2015 from the ... Shareholders, We would like to take this opportunity ...
(Date:1/22/2015)... DIEGO , Jan. 22, 2015  Profil Institute for ... on diabetes and obesity, announced today a new textbook,  ... Development,  published by Springer, a leading global scientific publisher. ... analyze and illustrate techniques for use in early phase ...
(Date:1/22/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/x3hp3g/microbiology ... "Microbiology Testing/Clinical Microbiology Market by Product, Clinical Application ... report to their offering. Clinical ... for the detection of infectious diseases. The respiratory ...
Breaking Medicine Technology:Pivotal Therapeutics: Year in Review and CEO Update 2Pivotal Therapeutics: Year in Review and CEO Update 3Pivotal Therapeutics: Year in Review and CEO Update 4Pivotal Therapeutics: Year in Review and CEO Update 5Pivotal Therapeutics: Year in Review and CEO Update 6Pivotal Therapeutics: Year in Review and CEO Update 7New Textbook "Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development" Provides Critical Review Of Current And Emerging Clinical Investigation Methods 2New Textbook "Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development" Provides Critical Review Of Current And Emerging Clinical Investigation Methods 3Global Microbiology Testing/Clinical Microbiology (Instrument, Analyzer, Incubator, Kit, Microscope, Molecular Diagnostics) Market - Forecast to 2019 2Global Microbiology Testing/Clinical Microbiology (Instrument, Analyzer, Incubator, Kit, Microscope, Molecular Diagnostics) Market - Forecast to 2019 3
... Scientific Corporation (NYSE: BSX ) today announced ... District of Delaware found that Cordis Corporation owed Boston ... which covers intellectual property associated with coronary stent technologies. ... $1 million in reasonable royalties to Boston Scientific. ...
... 2011 Applied Isotope Technologies (AIT), a company ... environmental, healthcare and industrial segments by applying its ... established operations in a 1,500 square foot analytical ... life sciences campus on the south side of ...
Cached Medicine Technology:Boston Scientific Announces Favorable Jury Verdict Against Cordis Corporation in Stent Patent Litigation 2Boston Scientific Announces Favorable Jury Verdict Against Cordis Corporation in Stent Patent Litigation 3Applied Isotope Technologies Opens New Facility in PLSG Life Sciences Campus 2
(Date:1/22/2015)... The Incredible Bulk is a revolutionary method put together by ... up to 30lbs in less than 12 weeks without traditional ... prompting an investigative review. , “Our Incredible Bulk review ... that allows the body to pack on a massive amount ...
(Date:1/22/2015)... 22, 2015 The federal court overseeing thousands ... District Court, Southern District of West Virginia has upheld a ... proceeding’s first bellwether trial. In an Order dated January 21st, ... after finding that C.R. Bard had not proven a miscarriage ...
(Date:1/22/2015)... 22, 2015 Autocarinsurancebest.com has released a new ... commercial auto insurance policy . , Auto insurance quotes ... It is no longer necessary to call an agent or ... available online on a single website: http://autocarinsurancebest.com/ . , ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 A ... Sports Medicine flagship journal Medicine & Science in ... before exercise may help reduce gastrointestinal (GI) problems ... , Participants in the double-blind, placebo-controlled study ...
(Date:1/22/2015)... 22, 2015 Four years since the release of ... coincided with the marriage of Avasa & Matthew Love – the ... is scheduled for release through White Swan Records on February 24, ... is a sacred path available to all of us to walk ...
Breaking Medicine News(10 mins):Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4
... different proteins interact with one another to enable self ... oxygen supply// to the tissue may eventually pave ... failure. ,Such self-destruction of the kidney can ... the kidney, removal of kidney during kidney transplantation and ...
... revolution of sorts. A clue into what might be ... at reducing// or totally obliterating the side-effects by evolving ... information. Indeed this will be a whole new story ... M. Issa, a pharmacologist and clinical epidemiologist is the ...
... one of the challenges of a relationship, even for couples deeply ... boyfriend// is something she can do without when she wants to ... but he isn't bothered by Lisa's desire not to. ... way it is now is completely OK with me." ...
... (ADAF) and the National Institute of Standards and Technology (NIST) ... the construction or repair of bones in the face, skull ... method for making scaffolds for bone tissue. The scaffold is ... a cement paste consisting of minerals, available in natural bone. ...
... Scientists have found that applying antiviral coating on bank ... help in fighting the epidemics//. ,Materials researcher ... has discovered a coating of metal, metal oxide and ... online edition of New Scientist. ,Applying ...
... to eradicate malnutrition among children, the state's Minister for ... ,The 'Bal Shakti Yojana' - strong child scheme ... health and the women and child development departments, Vishnoi ... and nutritional rehabilitation of severely malnourished children aims at ...
Cached Medicine News:Health News:New Research Offers Hope In Kidney FailureTreatment 2Health News:Sleeping Position Speaks A Lot About The Couples Relationship 2Health News:Sleeping Position Speaks A Lot About The Couples Relationship 3
Premier pouches provide the ultimate in skin protection with our long wearing Flextend skin barriers and superior comfort with our soft and silky ComfortWear panels....
Inquire...
... assay for the detection of the APC ... to activated protein C (APC). The test ... the anticoagulant function in vivo and provides ... inherited and acquired APC resistance. Detects the ...
Inquire...
Medicine Products: