Navigation Links
MicroConstants Now Offers Nanoparticle Formulation Services
Date:3/8/2010

SALT LAKE CITY, March 8 /PRNewswire/ -- MicroConstants, a GLP-compliant Contract Research Organization (CRO) specializing in bioanalytical and pharmacokinetic analysis, has acquired access to a new nanosizing technology that transforms water insoluble compounds into nanoparticles, making formulation preparation and dosing for toxicology studies easier. In multiple cases, our method has been proven to increase the gastro-intestinal absorption of highly insoluble compounds ensuring maximal oral exposure for toxicology studies.

Many commercially available medications and a large majority of New Chemical Entities (NCEs) produced are poorly soluble. For existing medications, this leads to costly and poorly absorbed medications that are minimally effective. For poorly soluble NCEs, higher doses, poor efficacy results and increased production costs often make them non-commercializable. Nanotechnologies have been proven as a valuable adjunct to the development of new therapeutics. Nanoparticles provide a much larger surface area thereby increasing the dissolution rate resulting in enhanced absorption. Nanosizing your compound elicits improved drug loading, exposure and bioavailability, and faster onset (earlier Tmax).

The patented, proprietary nanosizing process used at MicroConstants does not involve water or mechanical shear, so it is faster and more efficient than aqueous-based technologies. Furthermore, the process typically does not require the addition of excipients, leaving the pure Active Pharmaceutical Ingredient (API) ready for easy dispersion as a convenient suspension formulation. Our cost effective technique provides higher dose loading (50-60%), and is amendable to all routes of extravascular administration. The particle size is reproducible and the process is completely scalable.

If you are working with a difficult formulation or a compound with poor absorption, let MicroConstants transform your compound into nanoparticles. Visit us at booth 221 during the SOT Annual Meeting March 8-10, 2010 in Salt Lake City, Utah to learn more.

About MicroConstants

MicroConstants is a GLP-compliant Contract Research Organization (CRO) dedicated to providing premier quality bioanalytical, drug metabolism, pharmacokinetic, formulation and immunoassay support services to pharmaceutical and biotech companies worldwide. We are the largest bioanalytical LC/MS/MS service provider on the West Coast, and specialize in method development, method validation and sample analysis. For more information about our nanoparticle formulation services, or any of the services offered by MicroConstants, please visit our website at http://www.microconstants.com.

SOURCE MicroConstants

Back to top

RELATED LINKS
http://www.microconstants.com

'/>"/>

SOURCE MicroConstants
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Slo-Niacin(R) Offers More Than 20 Years of Heart Health Support
2. MedQuist Performance Monitor Offers Transparency, Detailed Reporting and Measurement of Clinical Documentation Metrics
3. International Merchant Advisors, Inc. Offers to Invest in Pharmaceutical Chain
4. Bionorica Offers Tips on Selecting Safe and Effective Natural Remedies for Children
5. Babson Executive Education Offers Bio-Pharma: Mastering the Business of Science
6. Blue Cross and Blue Shield of Illinois Offers Consumer Tips for Safe Disposal of Prescription Drugs
7. AstraZeneca Offers Online Enrollment and Additional Improvements to Patient Assistance Program
8. Inverness Medical Innovations Offers to Acquire Standard Diagnostics
9. GeoInvesting.com Offers Insight Into Two Growing Chinese Pharmaceutical Firms
10. Waismann Method Offers Safe and Alternative Treatment for Dependency to Ambien
11. Thomson Reuters Clinical Surveillance Solution Offers Powerful New Functionality to Improve Clinical Quality and Reduce Costs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2017)... YORKTOWN, N.Y. and EDMONTON, ... IBM ) scientists and the University of ... have published new data in Nature,s partner journal, ... learning algorithms helped predict instances of schizophrenia with ... technology predicted the severity of specific symptoms in ...
(Date:7/19/2017)... , July 19, 2017  Mako Medical Laboratories partnered ... the Military Family Assistance Fund (MFA) to bring 140 ... to visit with their families one last time before ... coordinate the travel and logistics needed for these soldiers. ... soldiers and their families. We just wish we could ...
(Date:7/13/2017)... WILLIAMSTON, Mich. , July 13, 2017  Centurion Medical Products, ... offers its DisImpactor ® fecal impaction removal device for hospice ... ... Patient pain management ... DisImpactor for Hospice can help alleviate patient pain while preventing unneeded ...
Breaking Medicine Technology:
(Date:7/26/2017)... ... July 26, 2017 , ... Isodiol International ... cannabis innovator, specializing in the development of pharmaceutical and consumer products, announces the ... to June 30, 2017. Iso International LLC recorded unaudited fiscal Q1 profits of ...
(Date:7/25/2017)... ... July 25, 2017 , ... “Now Hiring!” is a popular phrase at ... company has achieved record-breaking sales for over 30 consecutive years and now plans to ... The upcoming year offers excitement and growth at HDIS, following the company’s acquisition by ...
(Date:7/25/2017)... ... 25, 2017 , ... Therachat , a smart journaling ... providing demos of its smart journaling platform at the 125th American Psychological Association ... from August 3-6, 2017. , The APA Annual Convention is one of the ...
(Date:7/25/2017)... (PRWEB) , ... July 25, 2017 , ... ... Winner for its Product Innovation in the prestigious CEO World Awards®. The coveted ... performance, new products and services, CEO case studies, corporate social responsibility, and milestones ...
(Date:7/24/2017)... ... 24, 2017 , ... SignatureCare Emergency Center is looking to award ... semester to a deserving student. Get your applications in now as the deadline ... Mariana Castillo who is a nursing student at Prairie View A&M University with a ...
Breaking Medicine News(10 mins):