Navigation Links
MicroConstants Expands Biomarker Testing and Analysis Services for Preclinical and Clinical Diagnostic Research
Date:6/25/2013

SAN DIEGO, June 25, 2013 /PRNewswire/ -- MicroConstants, a Contract Research Organization (CRO) specializing in regulated bioanalysis and DMPK, announces the appointment of Doinita Serban, Ph.D. as director of biomarker research to oversee the expansion of biomarker testing and analysis services for preclinical and clinical diagnostic research. Doinita's extensive experience with biomarker assay development, validation, and profiling of disease panels, coupled with the implementation of the Luminex platform, will enable MicroConstants to broaden their biomarker analysis capabilities to include additional assay formats, such as multiplex immunoassays, gene expression and profiling assays.

Doinita brings to MicroConstants more than 15 years of experience in the pharmaceutical industry specializing in cancer and vascular biology, immunology, and bioanalysis in preclinical and clinical research. She has spent over 10 years developing and validating biomarker assays for biopharmaceuticals on a variety of instrumentation platforms to support clinical diagnostic research for various therapeutic areas, including oncology, inflammation, infectious and vascular diseases.

"Although multiplex biomarker assays are a new service offering for MicroConstants, Doinita's in-depth knowledge of biomarker analysis and pharmacodynamic targets will be a valuable asset to the department as we expand our capabilities," says David F. Beyerlein, vice president of global operations at MicroConstants. "These biomarker assays will provide our pharmaceutical and biotech clients with valuable insight into the efficacy of therapies for cancer and other complex diseases to help guide their decisions throughout all phases of drug development."

There is an urgent need for the discovery of biomarkers that can be used in blood-based, non-invasive molecular tests. These tests can be used to assist in the detection and diagnosis of diseases, to classify tissues and patients for clinical trials, and to monitor disease response to treatment and relapse. Furthermore, linking the molecular aberrations of diseases to drug responses can guide treatment choices and identify new therapeutic applications.

MicroConstants will use the Luminex platform to study the cellular fitness of engineered cells in response to a collection of drugs, enabling the systematic analysis of thousands of gene-drug interactions and unveiling of resistance mechanisms. The multiplex technology will also be used to perform both gene and protein expression assays. Custom assays can be created for genotyping and protein assessment (i.e. tyrosine kinases, growth factors etc.), and commercially available kits can be used to monitor cytokine levels.

About MicroConstants, Inc.

MicroConstants is a GLP-compliant Contract Research Organization (CRO) focused on performing regulated bioanalysis, drug metabolism and pharmacokinetic analysis to support discovery, preclinical and clinical drug development studies. They specialize in method development, method validation and sample analysis of small molecules, biopharmaceuticals, biomarkers and metabolites using LC/MS/MS, HPLC/UV, immunoassay and multiplex techniques. For more information, please visit http://www.microconstants.com.


'/>"/>
SOURCE MicroConstants
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. MicroConstants China Signs Site Management Organization Agreement with the Clinical Research Center of No. 307 Hospital
2. As Smartphone Usage Expands, Survey Says Nurses and Nursing Students Want Mobile Access to Credible Drug Data
3. BioSurplus Expands, Debuts New 8000 Square Foot Warehouse and Service Facility
4. RxAlly Expands National Network With Addition Of Nineteen Community Pharmacy Organizations Representing Over 2,000 Pharmacies
5. Clinical Interest in BioElectronics Products Expands to the Wound Care Market
6. S1 Biopharma Expands Focus to Include Male Sexual Health
7. PRA Expands Operations in Europe
8. USANA Health Sciences Expands Award-Winning Research and Development Team
9. Particle Sciences Expands its cGMP Capabilities with the Addition of Thin Films
10. Argus Expands Specialty Pharmacy with Amber Pharmacy Collaboration
11. Lilly Expands Strategic Partnership with Chinese Manufacturer Novast to Serve Chinese Patients with High-Quality Branded Generic Medicines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/23/2017)... , Südkorea, 23. Februar 2017 LG Innotek ... Sterilisationsaufgaben vorgestellt. Die Sterilisationsleistung beträgt das 1,5-fache des 45-mW-Moduls ... Strahlung im Bereich zwischen 200 und 280 nm und eignet ... Bakterien, indem es ihre DNA zerstört. Das Produkt von ... ...
(Date:2/23/2017)... Feb. 23, 2017 ITL Limited, ( ASX: ITD ), ... for the half year ended 31 December 2016 compared with the ... presentation can be viewed here . Highlights ... $1.04m; up 104%) Earnings per share of 2.2 ... of $17.5m (Dec 2015: $15.7m; up 11%) Profit ...
(Date:2/23/2017)... 2017 Research and Markets has announced the addition ... report to their offering. ... The latest research Menopause Drugs Price Analysis and Strategies - 2016, provides ... research answers the following questions: What are ... they positioned in the Global Menopause market? What are ...
Breaking Medicine Technology:
(Date:2/26/2017)... ... 2017 , ... Occupational pesticide exposure is linked to an ... according to a study released today at the 1st Pan American Parkinson’s and ... pesticides and incidence of sporadic PD through occupational exposure. This latest study, led ...
(Date:2/24/2017)... ... February 24, 2017 , ... ... replacement options at his office, Antoine Dental Center. Currently, patients can get single ... restrictions may apply, but patients can learn more about these offers by contacting ...
(Date:2/24/2017)... , ... February 24, 2017 , ... An in-depth computational ... the University of Pittsburgh points to eight genes that may explain why susceptibility to ... to the results of a study published today in the journal npj Schizophrenia. ...
(Date:2/24/2017)... ... , ... In the Health Care IT campaign, Robert Herjavec discusses health IT ... you will be attacked, but when.” However, he and many others involved highlight a ... Improvements in auditing and monitoring have taken security in health care a very long ...
(Date:2/24/2017)... ... , ... The narrative in “ Signal 8: An Australian Paramedic’s Story ” ... paramedic experiences. Schanssema describes the tragedies he saw, as well as his struggles with ... Schanssema, initially unsure of the career path he wanted to take, found fulfillment in ...
Breaking Medicine News(10 mins):