Navigation Links
MicroConstants Expands Biomarker Testing and Analysis Services for Preclinical and Clinical Diagnostic Research
Date:6/25/2013

SAN DIEGO, June 25, 2013 /PRNewswire/ -- MicroConstants, a Contract Research Organization (CRO) specializing in regulated bioanalysis and DMPK, announces the appointment of Doinita Serban, Ph.D. as director of biomarker research to oversee the expansion of biomarker testing and analysis services for preclinical and clinical diagnostic research. Doinita's extensive experience with biomarker assay development, validation, and profiling of disease panels, coupled with the implementation of the Luminex platform, will enable MicroConstants to broaden their biomarker analysis capabilities to include additional assay formats, such as multiplex immunoassays, gene expression and profiling assays.

Doinita brings to MicroConstants more than 15 years of experience in the pharmaceutical industry specializing in cancer and vascular biology, immunology, and bioanalysis in preclinical and clinical research. She has spent over 10 years developing and validating biomarker assays for biopharmaceuticals on a variety of instrumentation platforms to support clinical diagnostic research for various therapeutic areas, including oncology, inflammation, infectious and vascular diseases.

"Although multiplex biomarker assays are a new service offering for MicroConstants, Doinita's in-depth knowledge of biomarker analysis and pharmacodynamic targets will be a valuable asset to the department as we expand our capabilities," says David F. Beyerlein, vice president of global operations at MicroConstants. "These biomarker assays will provide our pharmaceutical and biotech clients with valuable insight into the efficacy of therapies for cancer and other complex diseases to help guide their decisions throughout all phases of drug development."

There is an urgent need for the discovery of biomarkers that can be used in blood-based, non-invasive molecular tests. These tests can be used to assist in the detection and diagnosis of diseases, to classify tissues and patients for clinical trials, and to monitor disease response to treatment and relapse. Furthermore, linking the molecular aberrations of diseases to drug responses can guide treatment choices and identify new therapeutic applications.

MicroConstants will use the Luminex platform to study the cellular fitness of engineered cells in response to a collection of drugs, enabling the systematic analysis of thousands of gene-drug interactions and unveiling of resistance mechanisms. The multiplex technology will also be used to perform both gene and protein expression assays. Custom assays can be created for genotyping and protein assessment (i.e. tyrosine kinases, growth factors etc.), and commercially available kits can be used to monitor cytokine levels.

About MicroConstants, Inc.

MicroConstants is a GLP-compliant Contract Research Organization (CRO) focused on performing regulated bioanalysis, drug metabolism and pharmacokinetic analysis to support discovery, preclinical and clinical drug development studies. They specialize in method development, method validation and sample analysis of small molecules, biopharmaceuticals, biomarkers and metabolites using LC/MS/MS, HPLC/UV, immunoassay and multiplex techniques. For more information, please visit http://www.microconstants.com.


'/>"/>
SOURCE MicroConstants
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. MicroConstants China Signs Site Management Organization Agreement with the Clinical Research Center of No. 307 Hospital
2. As Smartphone Usage Expands, Survey Says Nurses and Nursing Students Want Mobile Access to Credible Drug Data
3. BioSurplus Expands, Debuts New 8000 Square Foot Warehouse and Service Facility
4. RxAlly Expands National Network With Addition Of Nineteen Community Pharmacy Organizations Representing Over 2,000 Pharmacies
5. Clinical Interest in BioElectronics Products Expands to the Wound Care Market
6. S1 Biopharma Expands Focus to Include Male Sexual Health
7. PRA Expands Operations in Europe
8. USANA Health Sciences Expands Award-Winning Research and Development Team
9. Particle Sciences Expands its cGMP Capabilities with the Addition of Thin Films
10. Argus Expands Specialty Pharmacy with Amber Pharmacy Collaboration
11. Lilly Expands Strategic Partnership with Chinese Manufacturer Novast to Serve Chinese Patients with High-Quality Branded Generic Medicines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/4/2017)... -- According to the Centers for Disease Control and Prevention (CDC), influenza ... Care is helping communities across Massachusetts , ... no-cost* flu shots through the end of the month. *Some ... ... flu shot is by the end of October, according to the Centers ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
(Date:10/2/2017)... Denmark , Oct. 2, 2017 The Rebound ... in the struggle to reverse the tide of prescription drug ... for regulating their medicine intake and stepping down their dosage ... set to launch in December 2017; the first 100,000 people ... Learn more at http://www.rebound-solution.com/ ...
Breaking Medicine Technology:
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts ... Washington, D.C., for the 49th Congress of the International Society of Paediatric Oncology ... of the Center for Cancer and Blood Disorders at Children’s National, and ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... named one of Michigan’s 2017 Best and Brightest in Wellness® by Best and ... Wellness® awards program on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. ...
(Date:10/12/2017)... BALTIMORE (PRWEB) , ... October 12, 2017 , ... ... average of $3,296 in property taxes a year. In some states—like New York, ... higher. , By contrast, many overseas retirement havens have extremely low property-tax rates, ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... at the University of California Berkeley, and other leading institutions in announcing the ... power of institutions to change the way animals are raised for food. , ...
(Date:10/12/2017)... ... October 12, 2017 , ... Nvision Biomedical Technologies ... with the addition of industry sales leader, Thomas (Tom) Slott, as Senior Vice ... distribution and sales network, direct the efforts of the surgical sales teams, manage ...
Breaking Medicine News(10 mins):