Navigation Links
MicroConstants China In-licenses Phase 2 Liver Cancer Drug from Canadian Pertinax Therapeutics
Date:9/9/2013

BEIJING, Sept. 9, 2013 /PRNewswire/ -- MicroConstants China Inc. has signed a definitive agreement to in-license the China rights for a promising Phase 2 liver cancer drug, PTX-9908, from Pertinax Therapeutics of Canada. MicroConstants China will be responsible for funding the clinical development of PTX-9908 in China. Pertinax will receive a royalty in connection with the sales of the product in China, as well as any future assignment or transfer of the rights.

PTX-9908 is an analog of Stromal Derived Factor -1 (SDF-1), a major chemotactic factor that plays a significant role in mediating cell trafficking via selective binding to CXCR4. When PTX-9908 binds to CXCR4, it stops the cancer cells from spreading to other parts of the body, a process called metastasis.

PTX-9908 has been tested in healthy human volunteers and cancer patients in several Phase I/II clinical trials in North America. These studies showed PTX-9908 to be safe and well-tolerated in human and preliminary evidence of efficacy was observed. MicroConstants China will conduct clinical research in China to establish the efficacy, safety and tolerability of PTX-9908 in patients with unresectable hepatocellular carcinoma using PTX-9908 infused intravenously.

"Our collaboration with MicroConstants China will enable expedited development of PTX-9908 in China and give us the opportunity to provide a potentially life-saving treatment to a large number of liver cancer patients with limited treatment options," said Dr. Bev Incledon, president of Pertinax. "With MicroConstants China's expertise in global drug development and their GLP/GCP compliance record, I am confident that data generated in China will complement our global development of PTX-9908 for the treatment of other cancers."

"The execution of this licensing agreement with Pertinax verifies our business model and is an important milestone for us," said Dr. Q. David Yang, chief executive officer of MicroConstants China. "PTX-9908 is an excellent candidate for liver cancer and our partner Pertinax has extensive preclinical and clinical expertise to support further development of the compound in China."

About Pertinax Therapeutics Inc.
Pertinax Therapeutics is a specialty pharmaceutical company leveraging networks to acquire, enhance and partner undervalued human-experienced drug candidates. Its lead product, PTX-9908, and a portfolio of SDF-1 mimetics, have significant therapeutic potential in cancer and autoimmune disorders due to their extensive clinical experience and robust data packages.

Pertinax's affiliated company, Concept 2 Clinic Inc., is an executive R&D management company specialized in the pharmaceutical and biotechnology sectors. They provide R&D leadership and infrastructure to pharmaceutical sponsors requiring virtual drug development expertise. For more information, please visit http://www.concept2clinic.com.

About MicroConstants China Inc.
MicroConstants China is a Site Management Organization (SMO) and Contract Research Organization (CRO) located in Beijing, China. Established in 2007 by the president of MicroConstants, Inc. in San Diego, California, MicroConstants China is focused on providing clinical trial management services, regulated bioanalysis, pharmacokinetic studies and quality system consulting to pharmaceutical and biotech companies. They also implement ICH GCP quality systems and provide clinical site management services to clinical trial centers in China. For more information, please visit http://www.microconstants.com.cn.



'/>"/>
SOURCE MicroConstants China Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. MicroConstants China Signs Site Management Organization Agreement with the Clinical Research Center of No. 307 Hospital
2. MicroConstants Expands Biomarker Testing and Analysis Services for Preclinical and Clinical Diagnostic Research
3. Top buyers including Atico, Coles Group Asia, Kmart, Staples, Office Depot and Target Australia pre-registered to attend Global Sources spring China Sourcing Fairs
4. CentraState and Freehold Radiology Group train physicians from China
5. Johnson & Johnson (China) Investment Ltd. Acquires Guangzhou Bioseal Biotechnology Co., Ltd.
6. ResearchMoz: Global and China 4A Zeolite Industry 2012 Deep Research Report - Market Research Report
7. China Biologic Products to Host Earnings Conference Call on May 9, 2012 at 8:00 a.m. EDT (NY)
8. China Biologic Products Reports Higher Results for the First Quarter 2012
9. China Pharma Holdings, Inc. Reports First Quarter 2012 Financial Results
10. Osteoporosis Drug Market- Global And China Market Analysis, Size, Trends And Forecast (2010-2015)
11. China Botanic Attends 67th PHARMCHINA Fair
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... Research and Markets has announced ... Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality ... - Global Forecast to 2021" report to their ... global pharmaceutical excipients market is projected to reach USD ... in the forecast period 2016 to 2021. ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... Market Analysis 2016 - Forecast to 2022" report to ... report contains up to date financial data derived from varied ... major trends with potential impact on the market during the ... segmentation which comprises of sub markets, regional and country level ...
(Date:6/23/2016)... -- Bracket , a leading clinical trial technology and ... platform, Bracket eCOA (SM) 6.0, at the 52 nd ... 2016 in Philadelphia , Pennsylvania.  A demonstration ... of its kind to fully integrate with RTSM, will be ... is a flexible platform for electronic clinical outcomes assessments that ...
Breaking Medicine Technology:
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements ... was developed to enhance the health of felines. The formula is all-natural and is ... herbs in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library ... City Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ... for fumigation is not a common occurrence, but a necessary one in the event that ...
(Date:6/25/2016)... ... 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the ... to iHire in recognition of their exemplary accomplishments in worksite health promotion. , The ... Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... ... Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair ... hour by 2020 and then adjusting it yearly to increase at the same rate as ... the wage floor does not erode again, and make future increases more predictable. , The ...
Breaking Medicine News(10 mins):