Navigation Links
Michael J. Fox Foundation Awards $2 Million for Research on Cognitive and Mood Symptoms of Parkinson's Disease
Date:10/14/2008

ity of life. Dr. Schmand, who began his study with 120 people with PD and 70 controls, will now follow the remaining cohort of 90 patients and 60 controls with the objective of identifying early predictors of cognitive decline. Because preliminary data suggest that 20 percent of enrolled PD patients exhibited early cognitive impairment not observed in controls, extending the study should help detect further changes that will increase understanding of the phenomenology of cognitive changes in PD.

Connie Marras, MD, PhD, of the University of Toronto (Canada) will work to validate a well-known test for cognitive impairment, the Montreal Cognitive Assessment (MoCA), for diagnosing Parkinson's-related cognitive changes. Currently available tests for detecting cognitive impairment are either insensitive to the specific changes that occur in Parkinson's, test only some of the brain functions that can be impaired in PD-related dementia, and/or can be highly time-consuming. The MoCA, which takes less than 10 minutes to administer, could offer a wider window for detecting changes in PD patients. Dr. Marras will enroll 140 PD patients to take the MoCA questionnaire, whom she will then follow over time to determine the ability of MoCA to detect cognitive impairment in PD. Validation of the MoCA will provide a critical research tool needed to improve diagnosis of PD cognitive changes as well as for testing of novel therapeutics in future clinical trials.

Celeste Napier, PhD, of Rush University (USA) will work to shed light on the pathological gambling and other problems with impulse control that may be linked to dopamine replacement therapy in PD. While dopamine is involved with both the motor and reward systems, it is unclear why some Parkinson's patients exhibit reward-seeking behavior, particularly when taking dopaminergic drugs. Dr. Napier will combine preclinical models of Parkinson's disease and addictive behavior with the goal of developing a preclinical m
'/>"/>

SOURCE Michael J. Fox Foundation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Michael J. Fox Foundation Funds $1.1 Million for Cutting-Edge Approaches to Parkinsons Disease Under Rapid Response Innovation Awards 2008
2. Prepared Remarks of Attorney General Michael B. Mukasey Before the House Judiciary Committee
3. Michael J. Fox Foundation Awards $2.7 Million for Industry Efforts to Speed New Parkinsons Therapeutics
4. Michael J. Fox Foundation Awards $2.4 Million for Validation of Nine Promising Therapeutic Targets for Parkinsons Disease
5. The Foundation for Biomedical Research Announces Winners of the 7th Annual Michael E. DeBakey Journalism Awards
6. Michael J. Fox Foundation Announces $5.6-Million Award for Phase 2 Clinical Trial Studying Neuroprotective Potential of Inosine
7. Michael J. Fox Foundation Commits up to $10 Million for Pre-Clinical Drug Development Under Therapeutics Development Initiative
8. New Michael J. Fox Foundation Initiative Will Drive Development of Web-Based Tools to Increase Patient Participation in Parkinsons Clinical Trials
9. Michael J. Fox Foundation Commits Up to $3 Million for Clinical Trials That Can Improve Treatment of Parkinsons Disease
10. Michael J. Fox Foundation Awards Up to $3 Million to Industry Teams to Jumpstart Promising PD Drug Development
11. Alzheimers Foundation of America Survey: Americans With Memory Concerns Fall Short of Talking to Doctors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/14/2014)... 14, 2014 InformEx, North America,s ... chemistry, will hold the 30 th edition of its ... Convention Center from January 21-24. (Logo: http://photos.prnewswire.com/prnh/20131028/NY05330LOGO-a ... pharmaceutical, fine chemical and specialty chemical companies will take part ...
(Date:1/14/2014)... , Jan. 14, 2014 Animal Emergency Critical Care, a ... Leesburg, Virginia is the first in ... chamber. Dr. Susan M. Barnes , Medical ... Barnes and husband, Dr. Cole Taylor , are avid scuba ...
(Date:1/14/2014)... , January 14, 2014 ... Transfer Devices (CSTD) for hazardous drugs, today announced that it ... fourth straight year.   Equashield,s closed ... technicians, pharmacists, nurses and other medical professionals who ...
Breaking Medicine Technology:Media Advisory: InformEx 2014 Events & Speaker Lineup for 30th Edition Conference in Miami Beach 2Hyperbaric Veterinary Medicine (hvm) Announces Animal Emergency Critical Care Installs A Small Animal Hyperbaric Chamber 2Equashield's Sales Grow by 60% in 2013 2
... 9 BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX ) today ... the Company,s Board of Directors. Dr. Sanders brings to ... and professor of medicine. , "We are pleased ... Zola P. Horovitz, Ph.D., Chairman of the Board of BioCryst ...
... , LONDON, Dec. 9 ... $1 billion in the European Union (EU), which includes total ... anticholinergics used for disease symptom relief. With the introduction of ... guidelines that call for using dopamine agonists as first-line therapy, ...
Cached Medicine Technology:BioCryst Pharmaceuticals Elects Charles A. Sanders to its Board of Directors 2BioCryst Pharmaceuticals Elects Charles A. Sanders to its Board of Directors 3BioCryst Pharmaceuticals Elects Charles A. Sanders to its Board of Directors 4Drug Candidates in Pipeline Offer Potential for Parkinson's Disease Therapeutics Market, Says Frost & Sullivan 2Drug Candidates in Pipeline Offer Potential for Parkinson's Disease Therapeutics Market, Says Frost & Sullivan 3
(Date:7/9/2014)... occurrence of allergic diseases has risen dramatically in Western ... less exposed to microorganisms and have fewer infections than ... , A study by researchers at Sahlgrenska Academy, University ... to examine maturation of the immune system in relation ... rural areas of the Vstra Gtaland Region, half of ...
(Date:7/8/2014)... UCLA Program in Memory Restoration has been awarded up ... Agency (DARPA) for a four -year project aiming to ... team of experts in neurosurgery, engineering, neurobiology, psychology and ... a memory prosthesis in the brain. , Memory is ... the brain encode information, store it and retrieve it. ...
(Date:7/8/2014)... hygiene rates were found to be three times higher ... there were no auditors present, according to a study ... The study, titled, "Quantification of the Hawthorne effect in ... a retrospective cohort study," published today on-line in the ... author Dr. Jocelyn Srigley, who did the study as ...
(Date:7/8/2014)... have increased risks of dying at a young age ... stroke, diabetes, and kidney and liver diseases, according to ... large studies of people from three countries. The study, ... part of the National Institutes of Health, found that ... dramatic reduction in life expectancy compared with people of ...
(Date:7/8/2014)... LOUIS Military physicians will soon pick up joysticks instead ... children with serious health threats. , James Gerard, M.D., a ... $541,807 grant from the Department of Defense Office of ... develop a video game that will train physicians on pediatric ... to use one of the most popular tools gaming ...
Breaking Medicine News(10 mins):Health News:DARPA awards UCLA $15 million to restore lost memory 2Health News:DARPA awards UCLA $15 million to restore lost memory 3Health News:Health-care worker hand hygiene rates increase three-fold when auditors visible 2Health News:Health-care worker hand hygiene rates increase three-fold when auditors visible 3Health News:NCI study finds extreme obesity may shorten life expectancy up to 14 years 2Health News:Save, don't kill: SLU pediatrician to develop educational video game for training military physician 2
... MONDAY, Dec. 19 (HealthDay News) -- When it comes to toys, ... for parents, who find themselves asking two crucial questions. The ... safe for my child? And the second, though not as ... media aimed at spurring a child,s development: Which of these toys ...
... EDITOR,S PICK: Potential concern about drugs in clinical trial ... derived naturally in the body from a major component ... [EETs]) are currently in clinical trials for the treatment ... researchers led by Dipak Panigrahy and Mark Kieran, ...
... COLUMBUS, Ohio -- Drinking enough alcohol to become intoxicated increases ... according to new research. But people without that trait ... when they,re sober. That trait is the ability to ... focus on the here and now, without thinking about the ...
... 19 (HealthDay News) -- Knee pain is common in middle-aged and ... of data collected from nearly 500 women, ages 44 to 57, ... older reported persistent, incident or intermittent knee pain. Forty-four percent ... percent said they had knee pain on most days of the ...
... Known for her poetry, letters, love affair and marriage ... legacy of unanswered questions about her lifelong chronic illness. ... her daughter, may have unraveled the mystery. Born in ... weakness, heart palpitations, intense response to heat and cold, ...
... better quality of life (QOL) and diminished cardiovascular disease ... adenotonsillectomy, according to new research published in the December ... Surgery . SDB is an increasingly common ... apnea syndrome (OSAS). Cardiovascular (CV) disease frequently has been ...
Cached Medicine News:Health News:Discerning Gift-Givers Look for Toys That Offer More Than Fun 2Health News:Discerning Gift-Givers Look for Toys That Offer More Than Fun 3Health News:Discerning Gift-Givers Look for Toys That Offer More Than Fun 4Health News:JCI online early table of contents: Dec. 19, 2011 2Health News:JCI online early table of contents: Dec. 19, 2011 3Health News:JCI online early table of contents: Dec. 19, 2011 4Health News:JCI online early table of contents: Dec. 19, 2011 5Health News:JCI online early table of contents: Dec. 19, 2011 6Health News:JCI online early table of contents: Dec. 19, 2011 7Health News:1 trait has huge impact on whether alcohol makes you aggressive 2Health News:1 trait has huge impact on whether alcohol makes you aggressive 3Health News:Knee Pain Plagues Many Women Over 50 2Health News:Elizabeth Barrett Browning's illness deciphered after 150 years 2Health News:Elizabeth Barrett Browning's illness deciphered after 150 years 3Health News:Effect of adenotonsillectomy in children with sleep-disordered breathing 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: