Navigation Links
Michael J. Fox Foundation Awards $2.9 Million for Two New Parkinson's Disease Clinical Trials
Date:1/12/2009

NEW YORK, Jan. 12 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation for Parkinson's Research awarded about $2.9 million total for two clinical studies that will test drugs already approved in other disease indications for potential efficacy against Parkinson's disease. Because both drugs being tested are already known to be safe for humans, they hold potential to move swiftly toward regulatory approval for use in Parkinson's patients if they prove effective in PD.

One funded team will investigate the potential of simvastatin (marketed under the trade name Zocor), a drug currently used to treat high cholesterol, to reduce dyskinesias -- the disruptive, uncontrollable movements that are a side effect of long-term dopamine replacement. The other team will undertake a Phase 2 study to determine whether isradipine (marketed under the trade name Dynacirc), an approved high blood pressure medication, can rescue dopamine neurons from the degeneration seen in Parkinson's.

Although the drugs' current uses for cholesterol and blood pressure management might not seem relevant for PD, researchers found that the mechanisms by which each drug acts had unintended but beneficial effects on Parkinson's disease pathways in preclinical models of the disease.

The funding was awarded under the Foundation's Clinical Intervention Awards initiative, one of MJFF's three annually recurring Edmond J. Safra Core Programs for PD Research. The program supports novel or critical clinical intervention trials of promising therapeutic approaches that can significantly and fundamentally improve treatments for Parkinson's disease.

Funded projects are listed below. Detailed information, including grant abstracts and researcher bios, is available at www.michaeljfox.org.

A Randomized, Placebo-controlled, Multiple Crossover (n-of-1), Pilot tri
'/>"/>

SOURCE Michael J. Fox Foundation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Michael J. Fox Foundation Awards Up to $3 Million to Industry Teams to Jumpstart Promising PD Drug Development
2. Michael J. Fox Foundation Commits Up to $3 Million for Clinical Trials That Can Improve Treatment of Parkinsons Disease
3. New Michael J. Fox Foundation Initiative Will Drive Development of Web-Based Tools to Increase Patient Participation in Parkinsons Clinical Trials
4. Michael J. Fox Foundation Commits up to $10 Million for Pre-Clinical Drug Development Under Therapeutics Development Initiative
5. Michael J. Fox Foundation Announces $5.6-Million Award for Phase 2 Clinical Trial Studying Neuroprotective Potential of Inosine
6. The Foundation for Biomedical Research Announces Winners of the 7th Annual Michael E. DeBakey Journalism Awards
7. Michael J. Fox Foundation Awards $2.4 Million for Validation of Nine Promising Therapeutic Targets for Parkinsons Disease
8. Michael J. Fox Foundation Awards $2.7 Million for Industry Efforts to Speed New Parkinsons Therapeutics
9. Prepared Remarks of Attorney General Michael B. Mukasey Before the House Judiciary Committee
10. Michael J. Fox Foundation Funds $1.1 Million for Cutting-Edge Approaches to Parkinsons Disease Under Rapid Response Innovation Awards 2008
11. Michael J. Fox Foundation Awards $2 Million for Research on Cognitive and Mood Symptoms of Parkinsons Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)...  Today the U.S. Food and Drug Administration (FDA) announced ... serogroup B meningococcal disease in individuals ages ... received FDA approval in October, represent a significant step ... "I have heard over and over from parents ...
(Date:1/23/2015)... DES MOINES, Iowa , Jan. 23, 2015  The Partnership to ... Iowa health care leaders and a new study ... prescription medications. The PFCD is a nationwide coalition working to educate ... The research released at the Capitol was focused on how the ...
(Date:1/23/2015)... than a third of reproductive-aged women enrolled in Medicaid, and ... a prescription for an opioid pain medication each year during ... Mortality Weekly Report (MMWR). Opioids are typically ... pain.  They are also found in some prescription cough medications. ...
Breaking Medicine Technology:The National Meningitis Association (NMA) Applauds FDA Approval of Second Vaccine To Protect Against Serogroup B Meningococcal Disease 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3
... May 11 /PRNewswire-Asia-FirstCall/ -- China Nepstar Chain,Drugstore Ltd. (NYSE: ... China based on the number of directly operated stores,announced today that ... financial results to Tuesday, May 18, 2010 , before,market open. , ... The ...
... SHANGHAI, China , May 11 /PRNewswire-Asia/ -- ... research and development outsourcing company serving the,pharmaceutical, biotechnology, and medical ... United States , today announced its financial results for,first-quarter 2010. ... Highlights, -- First-Quarter 2010 ...
Cached Medicine Technology:China Nepstar Chain Drugstore Reschedules First Quarter 2010 Results to May 18 2China Nepstar Chain Drugstore Reschedules First Quarter 2010 Results to May 18 3WuXi PharmaTech Announces First-Quarter 2010 Results 2WuXi PharmaTech Announces First-Quarter 2010 Results 3WuXi PharmaTech Announces First-Quarter 2010 Results 4WuXi PharmaTech Announces First-Quarter 2010 Results 5WuXi PharmaTech Announces First-Quarter 2010 Results 6WuXi PharmaTech Announces First-Quarter 2010 Results 7WuXi PharmaTech Announces First-Quarter 2010 Results 8WuXi PharmaTech Announces First-Quarter 2010 Results 9WuXi PharmaTech Announces First-Quarter 2010 Results 10WuXi PharmaTech Announces First-Quarter 2010 Results 11WuXi PharmaTech Announces First-Quarter 2010 Results 12WuXi PharmaTech Announces First-Quarter 2010 Results 13WuXi PharmaTech Announces First-Quarter 2010 Results 14WuXi PharmaTech Announces First-Quarter 2010 Results 15WuXi PharmaTech Announces First-Quarter 2010 Results 16
(Date:1/22/2015)... its top dressmaking technologies, has been a leading dress supplier ... latest designs of wedding dresses and launching a site-wide promotion ... the fresh new products are designed for 2015, and they ... All the clothes from LunaDress follow up with the latest ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Gabe’s Chemo Duck Program ... App, the first app ever created for kids with cancer. The ... phones and devices, is filled with enjoyable games to help children ... treatments. The free app helps to keep kids entertained, educated and ...
(Date:1/22/2015)... 22, 2015 The Incredible Bulk is a ... to increase lean muscle by up to 30lbs in less ... attention of HealthyandFitZone.com’s Stan Stevenson, prompting an investigative review. , ... a step-by-step, scientific diet formula that allows the body to ...
(Date:1/22/2015)... 2015 AngelWeddingDress, the premier women’s dress ... wedding dresses. View website of AngelWeddingDress.com to ... maternity wedding dresses online for a bridal party. AngelWeddingDress ... quality for them. Its maternity wedding dresses are specially ...
(Date:1/22/2015)... A new white paper by The ... in the long-term care environment as well as provides ... The paper, “The Power of Person-Centeredness in Long-Term Care: ... of the patient, resident and family experience in long-term ...
Breaking Medicine News(10 mins):Health News:LunaDress Shows The Latest Styles Of Wedding Dresses In 2015 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3
... ... oral ingestion, and this is known to cause jitters and crashing effects. Now there,s a new ... pepper. Spray Awake is the world,s first personal energy spray to use capsaicin as a way ... ...
... 6 CEL-SCI Corporation (NYSE Amex: CVM ), a ... of infectious diseases and a late-stage oncology company, announced today ... School of Medicine (Johns Hopkins) has given clearance for the ... Johns Hopkins will host the study, which will be led ...
... Calif., Nov. 6 California American Water has designated the ... Drain" week for its Sacramento service area as part of ... toward the common mission of reducing pharmaceutical pollution in our ... household items free of charge at: , , ...
... ... the American Heart Association for the Start! Fit-Friendly Companies Award. , ... Covington, LA (PRWEB) November 6, 2009 ... award winning approach to health and lifestyle management and was recently honored with Platinum-Level ...
... CAMBRIDGE, Mass., Nov. 5 ETEX Corporation, an ... with Alphatec Spine, of Carlsbad, California. Alphatec Spine ... substitute portfolio on a non-exclusive basis in the ... http://www.newscom.com/cgi-bin/prnh/20080424/NETH117LOGO ) , Initial sales and ...
... ELA association and Zinedine Zidane, its emblematic ambassador, are ... regaring the gene therapy in adrenoleukodystrophy conducted in France ... Two children have been treated and their diseases have ... unexpected for a disease destroying the brain in a ...
Cached Medicine News:Health News:New Energy Spray Uses Capsaicin to Deliver Caffeine for Sustained Mental Focus 2Health News:CEL-SCI to Conduct First Clinical Study of Investigational LEAPS-H1N1 Treatment for Hospitalized H1N1 Infected Patients at Johns Hopkins University School of Medicine 2Health News:CEL-SCI to Conduct First Clinical Study of Investigational LEAPS-H1N1 Treatment for Hospitalized H1N1 Infected Patients at Johns Hopkins University School of Medicine 3Health News:California American Water Celebrates 'No Drugs Down the Drain' Week in Sacramento 2Health News:Gilsbar is Sole Louisiana Company to Win National Award from the American Heart Association 2Health News:ETEX Corporation Announces Distribution Agreement with Alphatec Spine 2Health News:ETEX Corporation Announces Distribution Agreement with Alphatec Spine 3Health News:2 children suffering from adrenoleukodystrophy saved thanks to the ELA Association 2Health News:2 children suffering from adrenoleukodystrophy saved thanks to the ELA Association 3Health News:2 children suffering from adrenoleukodystrophy saved thanks to the ELA Association 4
... drape sheets with a low-profile, roomy ... the operative site during arthroscopic surgery. ... ports for drainage. , ,The ... a standard pack, or in custom ...
The Quantum II Dual Wavelength Analyzer measures differential absorbances of liquid samples and converts those readings into analytical values....
... The ABBOTT PRISM is a fully ... enhance the safety of the blood supply. ... blood supply, it is tested for evidence ... disease. This screening process involves numerous assays, ...
... The First Consolidated Workstation to Automate ... Slide Staining,Now you can perform deparaffinization, ... and routine slide washing with a ... using preprogrammed Vysis protocols for fluorescence ...
Medicine Products: