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Micell Technologies Enrolls First Patient in CE Mark DESSOLVE II Study of MiStent™ Drug-Eluting Coronary Stent (DES)
Date:2/17/2011

ardiac events and revascularization rates, the extent of stent coverage and re-endothelialization, via optical coherence tomography (OCT), and endothelial function (vasomotor response) will be evaluated in a subgroup of patients at nine months.  More information on the DESSOLVE II trial can be found at ClinicalTrials.gov.

"Drug-eluting stents have significantly improved and expanded our ability to treat coronary atherosclerotic lesions compared to bare-metal stents," said William Wijns, M.D., Cardiovascular Center, Aalst, Belgium, and principal investigator of the study. "However, cardiologists are still looking for options to improve safety and outcomes. The MiStent DES may address some of these issues directly.  Based on recent GLP animal data, the polymer and drug are gone from the stent within 45 to 60 days.  This may reduce the risk of late-stent thrombosis related to long-term exposure to DES non-erodible polymers.  Given the relatively short residence time of polymer on the stent, MiStent DES may allow for a shorter duration of dual anti-platelet therapy and be a safer choice for non-compliant patients. These performance-enhancing properties are what interventional cardiologists are looking for in a new drug-eluting stent."

Arthur J. Benvenuto, Chairman and Chief Executive Officer of Micell, added, "The MiStent DES has the potential to uniquely combine safety and efficacy with excellent deliverability.  If these important patient benefits are confirmed in clinical trials, the MiStent DES performance and safety would be highly differentiated from both current DES offerings and from DES candidates known to be in development."

About the MiStent DESThe MiStent DES is a drug-eluting stent designed to optimize healing. The Company's rapid-absorbing drug/polymer formulation is inten
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SOURCE Micell Technologies Inc.
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