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Miami Jewish Home and Hospital, Berma Research Group and Segal Institute for Clinical Research Enrolling Local Patients in Study of Investigational Therapy to Treat Alzheimer's Disease
Date:11/12/2008

efficacy and safety results from the first pivotal trial showing that Dimebon improved the clinical course of Alzheimer's disease. In that study, patients treated with Dimebon showed significant improvement over patients treated with placebo (sugar pill) in each of the five most important aspects of Alzheimer's: memory, thinking, behavior, activities of daily living (such as eating and hygiene) and overall function. These improvements were seen after as little as 12 weeks of treatment with Dimebon and were maintained over a full year of treatment. Dimebon was well tolerated throughout the one-year treatment period.

About the CONNECTION Study

The CONNECTION study will enroll 525 patients in the United States -- as well as sites in Europe and South America -- to test the effects of Dimebon in patients with mild-to-moderate Alzheimer's disease. The study will evaluate the impact of Dimebon on cognition (thinking and awareness), memory, daily functioning, behavior and the ability to care for oneself.

Patients age 50 and older who are not taking any other Alzheimer's prescription medications may be eligible for the six-month study. Patients will randomly be chosen to receive either Dimebon or placebo. After six months of treatment, all patients -- including those receiving placebo -- will be offered the opportunity to receive Dimebon in an extension trial.

For more information on eligibility and enrollment, patients and caregivers can contact:

Miami Jewish Home & Hospital: 305-514-8503, http://www.mjhha.org

Berma Research Group: 305-702-9453, http://www.bermaresearch.com

Segal Institute for Clinical Research: 1-877-SEGAL-88,

http://www.segaltrials.com

CONNECTION study: 1-877-888-6386, http
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SOURCE Miami Jewish Home & Hospital; Berma Research Group; SegalInstitute
Copyright©2008 PR Newswire.
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