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MiStent SES demuestra ser único en el entorno clínico
Date:10/28/2013

tent SES

El sistema de stent coronario liberador de sirolimus y de polímero absorbente MiStent (MiStent SES®) se ha diseñado para optimizar el cicatrizado en los pacientes con enfermedad arterial coronaria. El recubrimiento de rápida absorción de MiStent tiene como objetivo controlar la liberación del fármaco de forma precisa y consistente y limitar la exposición del polímero para reducir los riesgos de seguridad asociados a las tecnologías de stent liberador de fármaco comercialmente disponible.

El innovador sistema MiStent SES incluye un recubrimiento de stent propio que contiene un fármaco cristalino (sirolimus) y un polímero absorbente. El recubrimiento proporciona liberación controlada y sostenida a niveles terapéuticos del fármaco, al tiempo que el polímero se reblandece y se dispersa desde el stent hasta dentro del tejido adyacente. Estas propiedades está previsto que mejoren la seguridad en comparación con los polímeros permanentes convencionales DES.

Usando un fármaco aprobado (sirolimus) y un polímero (PLGA), la tecnología de fluido supercrítico patentada de Micell permite un control riguroso del recubrimiento fármaco/polímero que se aplicará en un stent metálico. MiStent SES mejora los beneficios del sistema de stent coronario cobalto-cromo Genius® MAGIC de Eurocor (Marca CE), un stent metálico de última generación, que ha demostrado un suministro excelente, conformación y flexibilidad.

Los resultados realizados en estudios de animales han determinado que el recubrimiento se libera del stent en un periodo de entre 45 y 60 días, dejando el stent metálico y al polímero absorbido de forma completa dentro del tejido colindante a los 90 días para promover la permeabilidad a largo plazo y compatibilidad con la arteria.

Micell recibió la ap
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SOURCE Micell Technologies
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