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MiStent SES Shown to be Unique in Clinical Setting
Date:10/28/2013

DURHAM, N.C., Oct. 28, 2013 /PRNewswire/ -- Micell Technologies, Inc. today announced that imaging and clinical results from the DESSOLVE I and DESSOLVE II trials of its MiStent Sirolimus Eluting Absorbable Polymer Coronary Stent System (MiStent SES®) were presented at the 25th Annual Transcatheter Cardiovascular Therapeutics (TCT) Conference held in San Francisco, October 27 – November 1, 2013. The MiStent SES is a thin-strut drug-eluting stent distinguished by a rapidly absorbable coating designed to control drug release, and which was developed to optimize vessel healing in patients with coronary artery disease.

The data presentation, "MiStent: 2-year Randomized Trial Results from a Sirolimus-eluting Stent with a Bioabsorbable Coating," was part of the Scientific Symposium, "Next Generation DES and Bioabsorbable Scaffolds" conducted on Sunday, October 27.  John Ormiston, M.B.Ch.B., Interventional Cardiologist with the Mercy Angiography Unit, Auckland, New Zealand presented the data. Dr. Ormiston is a principal investigator in the DESSOLVE studies.

Two-year follow-up data from the DESSOLVE I and II trials were presented. The DESSOLVE I trial demonstrated minimal progression of late lumen loss between eight and 18 months follow up, with no target lesion MACE events through two years. The DESSOLVE II randomized trial two-year MACE rate was 6.7% for MiStent and 13.3% for Endeavor DES control group. There were no probable or definite stent thromboses related to MiStent use in either trial through two years. Detailed IVUS, angiographic and OCT imaging with endothelial function testing conducted across the two trials demonstrated bare-metal stent type healing with maintenance of normal endothelial function.

Dr. Ormiston commented, "MiStent is the only product in its class to optimize local drug delivery properties by providing up to nine
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SOURCE Micell Technologies
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