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Metamark Genetics Announces Cancer Cell Study Highlighting Discovery of Key Molecules that Drive Progression of Malignant Melanoma in Humans
Date:7/11/2011

are driving the aggressive behavior of melanoma. Further, when they are expressed across other tumor types they may play a similar role. This is supported by the fact that when we analyzed human breast cancer samples, some of these proteins were also able to predict the prognosis for patients with these tumors."

Metamark has exclusively licensed a portfolio of technologies, including those described in this manuscript, from the Dana Farber Cancer Institute. Based on the results of the Cancer Cell study, Metamark is developing a novel test for determining the prognosis of early stage melanoma.

"The reported Cancer Cell findings are of great importance for Metamark and further our efforts to predict the prognosis of early stage cancers, including malignant melanoma," said Peter Blume-Jensen, M.D., Ph.D., Chief Scientific Officer of Metamark. "This research is a concrete example of the value provided through the functional identification of molecules that play a direct role in tumor aggressiveness and supports Metamark's founding principle that early stage tumors contain key molecular information about their progression propensity. Our next goal is to incorporate markers such as these into molecular tests that will enable the identification of patients at high risk for progression independent of traditional risk parameters, such as lymph node status and thickness of the primary lesions."

This Cancer Cell study can be found at the following URL: http://www.cell.com/cancer-cell/abstract/S1535-6108(11)00195-4

About Metamark Genetics, Inc.

Metamark is a privately held oncology company focused on the development of function-based prognostic assays for early staged cancers. The MetamarkDx™ Prognostic Assays under development are based on Metamark's proprietary Prognosis Determinants™, genes discovered through leading edge ca
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SOURCE Metamark Genetics, Inc.
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