Navigation Links
Metamark Genetics Announces Cancer Cell Study Highlighting Discovery of Key Molecules that Drive Progression of Malignant Melanoma in Humans
Date:7/11/2011

CAMBRIDGE, Mass., July 11, 2011 /PRNewswire/ -- Metamark Genetics, Inc., a privately-held oncology-focused molecular diagnostics company, today announced results from a melanoma study published in Cancer Cell.  The study describes the identification and functional characterization of proteins that confer metastatic and invasive properties to early stage primary melanomas, the most deadly form of skin cancer in humans. The studies were conducted in the laboratories of Metamark Scientific Founders Lynda Chin, M.D., and Ron DePinho, M.D., from the Belfer Institute for Applied Sciences and Dana Farber Cancer Institute, and David Rimm, M.D., Ph.D. of Yale University.

"The findings from this study represent an important milestone in our efforts to predict whether or not an early melanoma lesion will eventually progress to metastatic and deadly disease," said Dr. Chin. "Moreover, since these proteins are functionally involved in the tumor progression, they are also potential drug target candidates."

Melanoma is a form a cancer that originates in pigment-forming cells, or melanocytes, and is most commonly found in the skin where it typically arises from moles. In the United States alone, there were 68,130 new cases of melanoma last year, and approximately 8,700 deaths from the disease.

Cancer Cell study investigators utilized a novel approach that involved integrating results from refined, genetically engineered mouse models with human cancer data and subsequent functional studies. The researchers were able to identify and validate six genes that are crucial for invasion and metastatic behavior of cutaneous melanomas.

"We believe that these findings significantly contribute to our molecular understanding of malignant melanoma with the potential to improve methods of defining prognosis and selection of optimal treatment strategies for patients with this disease," said Dr. Chin. "Our functional studies show that these proteins
'/>"/>

SOURCE Metamark Genetics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Metamark Genetics Partners with Definiens on Tissue-Based Cancer Diagnostics
2. Signal Genetics and DiagnoCure Announce a US$13.3M Collaboration for the Commercialization of Previstage™ GCC Colorectal Cancer Staging Test
3. Research 2.0 Updates Coverage of Viral Genetics with Research Report Focused on VG Energy
4. Viral Genetics Updates HIV/AIDS and Drug Resistant Cancer Research Programs
5. Signal Genetics Announces Commercialization Partnership with NeoGenomics Laboratories for Multiple Myeloma Gene Expression Test
6. USP Hospitales of Spain to Offer Interleukin Genetics Heart Health Test Throughout Its Hospital Network
7. Interleukin Genetics and Metagenics Initiate Research Collaboration
8. Technology Collaboration Between New England Biolabs and Sequenom Delivers First Product for Epigenetics
9. LABS, Inc. Announces Alliance with Ambry Genetics to Expand Testing Solutions for the Reproductive Health Industry
10. RainDance Technologies and Ambry Genetics Expand Collaboration to Address ADME Analysis
11. JS Genetics Develops New Non-Invasive Test, XCAT-TS, to Help Doctors Diagnose Turner Syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... Research and Markets ( http://www.researchandmarkets.com/research/vzhr6h/video ) has announced ... Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020" ... been the topic of fascination since the era of the ... and the Soviet Russia. Earlier even a small glimpse of ...
(Date:1/23/2015)...  Northwest Biotherapeutics, Inc. (NASDAQ: NWBO )("NW Bio"), a ... and inoperable solid tumor cancers, announced today that CEO ... Annual Phacilitate Immunotherapy Forum in Washington D.C. ... place on January 26 at 10:30 a.m. EST at the ...
(Date:1/23/2015)... all-time hits leader, is the new spokesperson for the topical ... announced. "Pete,s a Hall of Famer in our ... with Myoflex," said Ducere Pharma Chief Executive Officer Chris ... across all generations. The passion and intensity that Pete brought ...
Breaking Medicine Technology:Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3Pete Rose bets on Myoflex to relieve aches and pains 2
... MediSapiens Ltd , a Finnish bioinformatics company, has released the ... use. The data is available through a graphical tool, ... Ltd , allowing exploration of the expression activity of genes ... sequencing of the human genome, understanding which genes are expressed ...
... Systems (NYSE: VAR ) announced today that it ... following the close of regular trading on Thursday, October 27, ... available to all interested parties at 2:00 p.m. PT.  The ... will be available on the company website at: www.varian.com/investor ...
Cached Medicine Technology:Transcriptome Viewer - Comprehensive Genome-wide Map of Human Gene Expression Activity Released for Public by MediSapiens 2Varian Medical Systems Schedules Fourth Quarter FY2011 News Release and Conference Call 2
(Date:1/22/2015)... New York, New York (PRWEB) January 22, 2015 ... filed after Fresenius Medical Care recalled its GranuFlo ... the federal multidistrict litigation underway in U.S. District Court, ... an Order dated January 20th, the Court has remanded ...
(Date:1/22/2015)... NJ (PRWEB) January 22, 2015 Joan ... and keynote speaker at the upcoming 32nd Annual ... ACCME-accredited Physicians’ Education Resource®, LLC (PER®) , shares ... would have gone undetected if she had not followed ...
(Date:1/22/2015)... IsoComforter, Inc. has introduced the most innovative ... design to treat specific body parts and muscle groups. , ... easy to use patented cold therapy machine with the innovative ... and muscle injuries. IsoComforter has become the industry leader ...
(Date:1/22/2015)... As interest in the value of spiritual support as ... Rev. Eric J. Hall , president and CEO of the ... the keynote speaker on January 27 at an international summit ... The conference, “Hope and Resilience: Innovative and Interdisciplinary Spiritual Care,” ...
(Date:1/22/2015)... 22, 2015 Step into a macabre ... Science Museum of Virginia. Wicked Plants, the Museum’s latest ... unearths 75 poisonous, carnivorous and diabolical plants inside of ... to uncover the biochemical, physical and neurological processes between ...
Breaking Medicine News(10 mins):Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Wicked Plants are taking over the Science Museum of Virginia 2
... ... feature that allows project managers to find out about changes across multiple projects in ... ... a leader in online project management software innovations, sets a new project ...
... to return to normal state of alertness , WEDNESDAY, June ... of having to start the day without a cup of ... way. , Regular coffee drinkers seem to need caffeine to ... the side effects of caffeine withdrawal such as headaches. That ...
... Minority organ donations have more than doubled since the ... new retrospective study published in the May issue of the ... 2010, the percentage of minority donors is expected to reach ... Since the first organ transplant in 1954, the shortage of ...
... are reporting development of the first "dipstick" test for instantly ... a few pennies. Their study on the test, which involves ... strip, appears in ACS, semi-monthly journal Analytical Chemistry , ... health care in developing countries. The test also could be ...
... After years of research and anticipation, insulin pills that could ... diabetes are finally moving ahead in clinical trials and a ... in a two-part cover story on drug manufacturing in the ... C&EN ), ACS, weekly newsmagazine. C&EN ...
... -- Cancer-related fatigue is often a major problem ... and after completing therapy. Researchers at Mayo Clinic ... Treatment Group ( http://ncctg.mayo.edu/ ) (NCCTG) recently completed ... cancer-related fatigue and found that, while it did ...
Cached Medicine News:Health News:Wrike Introduces a Game-Changing Microblogging Tool for Project Managers 2Health News:Coffee's Jolt Just an Illusion? 2Health News:Coffee's Jolt Just an Illusion? 3Health News:Grassroots programs to encourage minority organ donation prove successful 2Health News:Results from a study testing methylphenidate for cancer-related fatigue 2Health News:Results from a study testing methylphenidate for cancer-related fatigue 3
... capability to quickly deliver up to 250 ... for powerful single-pulse ablation. This type of ... coldest and cleanest CO2 surgical laser available ... with the independent adjustment of pulse energy ...
... is a new CO2 laser system with ... panel and an exclusive design for easy ... SmarXide is the leader in a ... traditional features of Dekas laser devices, like ...
... removal for all skin types, ... for leg and facial veins, ... a large spot sizes with ... treatment. An optional scanner ...
... through an ultra thin flexible 400 - 1000 ... of movement when performing surgery. The MedArt® ... of handpieces. Handpieces are supplied with standard ... Straight and angled fiber guides with different ...
Medicine Products: