Navigation Links
Metabolic Solutions Development Company presents Phase 2a clinical trial results at the 14th International Conference on Alzheimer's Drug Discovery
Date:9/9/2013

KALAMAZOO, Mich., Sept. 9, 2013 /PRNewswire/ -- Metabolic Solutions Development Company, LLC (MSDC) has announced that Jerry Colca, PhD, co-founder and chief scientific officer of MSDC, will present results of a Phase 2a study on September 9 at the 14th International Conference on Alzheimer's Drug Discovery. In people with dementia due to Alzheimer's disease (AD) who were not diabetic, the study found that the mTOT™-modulating insulin sensitizer (MSDC-0160) maintained glucose metabolism in key regions of the brain associated with cognitive decline due to AD, as confirmed by FDG-PET imaging.

(Photo: http://photos.prnewswire.com/prnh/20130909/CG75830-INFO )

Glucose is a major energy source for cells, and alterations in glucose metabolism by nerve cells (neurons) in the brain have been associated with AD pathology.[1],[2]  Moreover, reduced brain glucose metabolism is region specific.[3],[4],[5]  In this study, in participants treated with placebo, the measure of glucose uptake significantly declined in key regions of the brain associated with cognitive decline in persons with dementia due to Alzheimer's disease; however,  this did not occur in the subjects treated with MSDC-0160.

"We are in urgent need of new approaches in Alzheimer's drug research because there are currently no approved therapies to halt or even slow progression of the disease," said Howard Fillit, MD, Executive Director and Chief Science Officer of the Alzheimer's Drug Discovery Foundation. "The mitochondrially-targeted insulin sensitizers are an exciting new class of drugs in Alzheimer's disease. The current results provide the basis for further clinical investigation of MSDC-0160 in Alzheimer's patients."

"Evaluation of an mTOT Mo
'/>"/>

SOURCE Metabolic Solutions Development Company, LLC
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. KemPharms KP201 Demonstrates Complete Metabolic Cleavage of Prodrug and Steady-State Pharmacokinetic Profiles for Hydrocodone, Hydromorphone and Acetaminophen
2. Metabolic Solutions Development Company announces publication of data describing potential for new drugs to maintain pancreatic beta-cells in treating diabetes
3. Unigene and Nordic Bioscience Enter Equity Transfer and Exclusive License Agreement for Proprietary Metabolic Peptide Analogs
4. Abide Therapeutics Announces Collaboration With Merck to Develop Novel Therapies for Type 2 Diabetes and Metabolic Diseases
5. Oramed Pharmaceuticals Chosen to Present at the 5th International Congress on Prediabetes and the Metabolic Syndrome in Vienna, Austria; April 18-20, 2013
6. Metabolic Solutions Development Company Awarded Funding by The Michael J. Fox Foundation
7. Metabolic Solutions Development Company announces publication of Phase 2b data in Clinical Pharmacology & Therapeutics
8. Isis Pharmaceuticals Reports Positive Phase 1 Data On Three Drugs In Development To Treat Metabolic Disorders
9. Polaris Group Lead Therapeutic Candidate ADI-PEG 20 Demonstrates Potential Anticancer Activity in Various Metastatic Sarcomas and Bladder Cancers That Are Deficient in Key Metabolic Protein, and Enhanced Effects with Combination Therapy in Melanoma
10. Profil Institute Partners with Florida Hospital to Establish East Coast Center for Clinical Metabolic Research
11. Sound World Solutions Expands Distribution Of The CS10 Personal Sound Amplifier
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... 2014 Research and Markets has ... Industry Report, 2014-2017" report to their offering. ... proportion of reimbursement for medical expenses, the Chinese orthopedic ... scale presenting a CAGR of 19.2% during 2009-2013. Trauma ... segments of orthopedic instruments in China ...
(Date:8/29/2014)... , Aug. 29, 2014 Research ... "Research and Development Trend Forecast of Pharmaceutical Equipment ... Research and Development Trend Forecast of ... 2014-2018 mainly analyzes China,s pharmaceutical ... supply & demand, competition landscape, and business performance of ...
(Date:8/29/2014)... , Aug. 29, 2014  Unilife Corporation ("Unilife" or ... today that it intends to release its financial results ... June 30, 2014 after market trading ends on Tuesday, ... a conference call for 4:30 p.m. U.S. EDT on ... 6:30 a.m. AEST), to review the Company,s financial results, commercial ...
Breaking Medicine Technology:China Orthopedic Instrument Industry Report, 2014-2017 2Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2Unilife Corporation to Announce Financial Results for Fiscal Year 2014 Fourth Quarter and Year End on Tuesday, September 9, 2014 2
... May 4, 2007 – Isotechnika Inc.,(TSX:ISA) announced today that ... our partner Lux Biosciences, has,been selected as the subject ... and Ophthalmology (ARVO) annual,meeting, being held May 6-10 in ... an oral presentation being given on May 5 during ...
... Conn.--(BUSINESS WIRE)--May 7, 2007 - NanoViricides,Inc. (Pink Sheets: ... and BSL3 in vitro studies against a Clade ... Symposium of the Pan,American Society for Clinical Virology ... Society for Clinical Virology (PASCV):,Clinical Virology Symposium), The ...
Cached Medicine Technology:Isotechnika's Lead Drug, ISA247, To Be Highlighted at the,Association for Research in Vision and Ophthalmology (ARVO) Annual,Meeting 2Isotechnika's Lead Drug, ISA247, To Be Highlighted at the,Association for Research in Vision and Ophthalmology (ARVO) Annual,Meeting 3Isotechnika's Lead Drug, ISA247, To Be Highlighted at the,Association for Research in Vision and Ophthalmology (ARVO) Annual,Meeting 4NanoViricides Drugs Found To Be Highly Effective Against Most,Recent Strain of the H5N1 Avian Flu Virus 2
(Date:8/30/2014)... Daily Gossip reveals in its review a program created ... who shows a unique formula to get inside a man’s ... that the program goes beyond mere attraction and actually helps ... indicates that the program was created by dating expert Alex ... to make a man feel emotionally addicted. , Learn more ...
(Date:8/30/2014)... 2014 RB SEO Services, a well-recognized ... for small businesses. , RBSEO Services knows this very ... search engine optimization service. So, the company has introduced ... account. , On being asked about the service, ... low cost SEO service because many small businesses expressed ...
(Date:8/30/2014)... Market Research Report on Global ... professional and in-depth market survey on Global and ... the basic information of Cell Disruptor including its ... explores global and China’s top manufacturers of Cell ... and market share etc. The report further analyzes ...
(Date:8/30/2014)... By Randy Dotinga ... -- About one in five patients operated on for broken ... after surgery, a new study finds. Less-educated patients ... times more likely to be "doctor shoppers," said study lead ... Lexington, Ky. Overall, he said, the study suggests that doctors ...
(Date:8/30/2014)... Dallas, Texas (PRWEB) August 30, 2014 ... Lab Oven Industry, 2009-2019 is a professional and ... Oven industry. The report firstly reviews the basic ... and manufacturing technology. The report then explores global ... their product specification, capacity, production value, and market ...
Breaking Medicine News(10 mins):Health News:Make Him Desire You Review Reveals Powerful Formula to Make a Man Emotionally Addicted 2Health News:RBSEO Services Introduces Low Cost SEO Service for Small Businesses 2Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 2Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 3Health News:Cell Disruptor Industry Global and Chinese Analysis for 2009-2019 in New Research Report at ReportsnReports.com 4Health News:'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds 2Health News:'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds 3Health News:Lab Oven Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 2Health News:Lab Oven Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 3Health News:Lab Oven Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 4
... In a promising development for cancer patients in New ... at Hackensack University Medical Center announced today that it ... to acquire an innovative system that enables a radically ... known as the TrueBeam system. The new radiotherapy system ...
... years after the signing of the Americans with Disabilities ... to measure whether public facilities are in compliance. ... who is reasonably intelligent but not necessarily a techie," ... Technology Research Institute (ATRI) at Misericordia University in Dallas, ...
... Va., July 16, 2010Framing climate change as a public ... significant and understandable to members of the publiceven some ... to preliminary research by George Mason University,s Center for ... an exploratory study in the United States of people,s ...
... MD, associate professor at Case Western Reserve University and ... primary affiliate, has received nearly $500,000 from Susan G. ... study aimed at improving outcomes for older women with ... expectancy coupled with aging as a risk factor for ...
... HealthDay Reporter , SUNDAY, July 18 (HealthDay News) ... flu vaccine through a stick-on skin patch instead of a ... containing tiny, painless "microneedles" to deliver the influenza vaccine may ... microneedles -- less than 1 millimeter in length, or about ...
... Reporter , FRIDAY, July 16 (HealthDay News) -- High heels ... of wearing them is even steeper than the sky-high price ... feet and a variety of foot deformities, years of high-heel ... and tendons, according to a study by researchers in England, ...
Cached Medicine News:Health News:John Theurer Cancer Center first cancer center in N.J. to acquire new radiotherapy system 2Health News:John Theurer Cancer Center first cancer center in N.J. to acquire new radiotherapy system 3Health News:Toolkit allows anyone to test for ADA compliance 2Health News:Toolkit allows anyone to test for ADA compliance 3Health News:When climate change becomes a health issue, are people more likely to listen? 2Health News:Susan G. Komen awards Case Western Reserve nearly $500,000 to study breast cancer in older women 2Health News:Susan G. Komen awards Case Western Reserve nearly $500,000 to study breast cancer in older women 3Health News:Flu Vaccine Via Skin Patch Shows Promise in Mice 2Health News:Flu Vaccine Via Skin Patch Shows Promise in Mice 3Health News:Those To-Die-For High Heels May Alter Anatomy 2Health News:Those To-Die-For High Heels May Alter Anatomy 3
... are designed for endomyocardial biopsies. The ... 3-pull ring handle, stainless steel cutting jaws, and ... to accommodate any position. ,A spring in the ... are opened by moving the double rings away ...
The only solution for in-line digital measurement...
A highly precise stereotactic radiosurgery system for the treatment of intra-cranial lesions....
Clinac EX Platinum accelerators offer all the high performance features of the EX series and come with the latest high-precision dose sculpting technology for advanced tumor control....
Medicine Products: