Navigation Links
Metabolic Solutions Development Company presents Phase 2a clinical trial results at the 14th International Conference on Alzheimer's Drug Discovery
Date:9/9/2013

KALAMAZOO, Mich., Sept. 9, 2013 /PRNewswire/ -- Metabolic Solutions Development Company, LLC (MSDC) has announced that Jerry Colca, PhD, co-founder and chief scientific officer of MSDC, will present results of a Phase 2a study on September 9 at the 14th International Conference on Alzheimer's Drug Discovery. In people with dementia due to Alzheimer's disease (AD) who were not diabetic, the study found that the mTOT™-modulating insulin sensitizer (MSDC-0160) maintained glucose metabolism in key regions of the brain associated with cognitive decline due to AD, as confirmed by FDG-PET imaging.

(Photo: http://photos.prnewswire.com/prnh/20130909/CG75830-INFO )

Glucose is a major energy source for cells, and alterations in glucose metabolism by nerve cells (neurons) in the brain have been associated with AD pathology.[1],[2]  Moreover, reduced brain glucose metabolism is region specific.[3],[4],[5]  In this study, in participants treated with placebo, the measure of glucose uptake significantly declined in key regions of the brain associated with cognitive decline in persons with dementia due to Alzheimer's disease; however,  this did not occur in the subjects treated with MSDC-0160.

"We are in urgent need of new approaches in Alzheimer's drug research because there are currently no approved therapies to halt or even slow progression of the disease," said Howard Fillit, MD, Executive Director and Chief Science Officer of the Alzheimer's Drug Discovery Foundation. "The mitochondrially-targeted insulin sensitizers are an exciting new class of drugs in Alzheimer's disease. The current results provide the basis for further clinical investigation of MSDC-0160 in Alzheimer's patients."

"Evaluation of an mTOT Mo
'/>"/>

SOURCE Metabolic Solutions Development Company, LLC
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. KemPharms KP201 Demonstrates Complete Metabolic Cleavage of Prodrug and Steady-State Pharmacokinetic Profiles for Hydrocodone, Hydromorphone and Acetaminophen
2. Metabolic Solutions Development Company announces publication of data describing potential for new drugs to maintain pancreatic beta-cells in treating diabetes
3. Unigene and Nordic Bioscience Enter Equity Transfer and Exclusive License Agreement for Proprietary Metabolic Peptide Analogs
4. Abide Therapeutics Announces Collaboration With Merck to Develop Novel Therapies for Type 2 Diabetes and Metabolic Diseases
5. Oramed Pharmaceuticals Chosen to Present at the 5th International Congress on Prediabetes and the Metabolic Syndrome in Vienna, Austria; April 18-20, 2013
6. Metabolic Solutions Development Company Awarded Funding by The Michael J. Fox Foundation
7. Metabolic Solutions Development Company announces publication of Phase 2b data in Clinical Pharmacology & Therapeutics
8. Isis Pharmaceuticals Reports Positive Phase 1 Data On Three Drugs In Development To Treat Metabolic Disorders
9. Polaris Group Lead Therapeutic Candidate ADI-PEG 20 Demonstrates Potential Anticancer Activity in Various Metastatic Sarcomas and Bladder Cancers That Are Deficient in Key Metabolic Protein, and Enhanced Effects with Combination Therapy in Melanoma
10. Profil Institute Partners with Florida Hospital to Establish East Coast Center for Clinical Metabolic Research
11. Sound World Solutions Expands Distribution Of The CS10 Personal Sound Amplifier
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... 2014   Acutus Medical, Inc. (ACM), ... 3D Cardiac Chamber Imaging and Dipole Density Mapping system ... sustain complex cardiac arrhythmias, including atrial fibrillation, announced it ... its imaging/mapping system as well as bring to market ... Medical to complete work on the AcQMap TM ...
(Date:9/30/2014)... PAUL, Minn. , Sept. 30, 2014 ... the United States abused prescription pain relievers ... include detoxification or maintenance treatment, which entails the use ... costs of these treatments are important when developing and ... by pharmacy benefit manager Prime Therapeutics LLC ...
(Date:9/30/2014)... Calif. , Sept. 30, 2014  Life ... group focused on supporting promising emerging biotech, medical ... been named the Top Angel Investment Group in ... as the best performer out of 370 angel ... historical performance, network strength (connections), selection aptitude and ...
Breaking Medicine Technology:Acutus Medical, Inc. Completes Additional $26.2M Series B Financing to Fund Portfolio Expansion 2Acutus Medical, Inc. Completes Additional $26.2M Series B Financing to Fund Portfolio Expansion 3Studies show cost and use of opioid dependence treatment are increasing, spurring the need for care management programs 2Studies show cost and use of opioid dependence treatment are increasing, spurring the need for care management programs 3Life Science Angels Ranked the Top Angel Investment Group in the U.S. 2Life Science Angels Ranked the Top Angel Investment Group in the U.S. 3
... FORT WASHINGTON, Pa., Nov. 13 ReSearch Pharmaceutical Services, ... integrated clinical development outsourcing solutions to the bio-pharmaceutical industry, ... quarter and nine months ended September 30, 2009. ... the quarter and nine months ended September 30, 2008. ...
... Calif., Nov. 13 Walt Maclay, President of ... been selected to speak on "Data Acquisition for ... 9, 2009. BIOMEDevice ( http://www.devicelink.com/expo/biomed09/index.html ) ... leaders in medical devices. The show offers a ...
Cached Medicine Technology:ReSearch Pharmaceutical Services, Inc. Unaudited Quarterly Report for the Period Ended September 30, 2009 2ReSearch Pharmaceutical Services, Inc. Unaudited Quarterly Report for the Period Ended September 30, 2009 3ReSearch Pharmaceutical Services, Inc. Unaudited Quarterly Report for the Period Ended September 30, 2009 4ReSearch Pharmaceutical Services, Inc. Unaudited Quarterly Report for the Period Ended September 30, 2009 5ReSearch Pharmaceutical Services, Inc. Unaudited Quarterly Report for the Period Ended September 30, 2009 6ReSearch Pharmaceutical Services, Inc. Unaudited Quarterly Report for the Period Ended September 30, 2009 7ReSearch Pharmaceutical Services, Inc. Unaudited Quarterly Report for the Period Ended September 30, 2009 8ReSearch Pharmaceutical Services, Inc. Unaudited Quarterly Report for the Period Ended September 30, 2009 9ReSearch Pharmaceutical Services, Inc. Unaudited Quarterly Report for the Period Ended September 30, 2009 10ReSearch Pharmaceutical Services, Inc. Unaudited Quarterly Report for the Period Ended September 30, 2009 11Voler Systems President Speaks at BIOMEDevice San Jose 2Voler Systems President Speaks at BIOMEDevice San Jose 3
(Date:10/1/2014)... Chicago IL (PRWEB) October 01, 2014 ... it has launched a new Other-Sonic Ultrasound ... public with information about the litigation surrounding the ... William Beaumont Hospital in Royal Oak, Michigan, which ... gel. The Firm is representing William Beaumont patients ...
(Date:10/1/2014)... Indosoft, Inc., a leading provider of scalable Asterisk-based ... added support for Sangoma Lyra Answering Machine Detection ... a history of bringing innovative products to market in the ... benefit to those using Asterisk as a platform for their ... of Q-Suite. , In the past decades, outbound call centers ...
(Date:10/1/2014)... 2014 The annual Social Security cost-of-living adjustment ... says a new forecast by The Senior Citizens League ... index (CPI) data through August, TSCL forecasts that COLAs will ... sixth consecutive year of record low COLAs,” states TSCL Chairman, ... automatic in 1975,” he notes. , Over the past five ...
(Date:10/1/2014)... October 01, 2014 QueenBeeTickets.com is giving music ... the singer’s upcoming North American tour, which has him traveling ... come. , Click here to view the selection ... performer’s newest album, is due to come out on October ... shortly thereafter. Bob Seger concert tickets are available for shows ...
(Date:9/30/2014)... same time could stop them from becoming resistant to ... Research * today (Wednesday). , The researchers, ... MedImmune, the global biologics research and development arm of ... two treatments helped the immune system hunt down and ... radiotherapy in mice with breast, skin and bowel cancers. ...
Breaking Medicine News(10 mins):Health News:Other-Sonic Ultrasound Gel Lawsuit Page Launched by The Oliver Law Group P.C. To Provide Information On Pseudomonas Outbreak Linked to Recalled Ultrasound Gel 2Health News:Other-Sonic Ultrasound Gel Lawsuit Page Launched by The Oliver Law Group P.C. To Provide Information On Pseudomonas Outbreak Linked to Recalled Ultrasound Gel 3Health News:Other-Sonic Ultrasound Gel Lawsuit Page Launched by The Oliver Law Group P.C. To Provide Information On Pseudomonas Outbreak Linked to Recalled Ultrasound Gel 4Health News:Indosoft Announces Q-Suite Support For Sangoma Lyra 2Health News:The Senior Citizens League (TSCL) Says Sixth Consecutive Year Of Record Low COLAs “Unprecedented” 2Health News:The Senior Citizens League (TSCL) Says Sixth Consecutive Year Of Record Low COLAs “Unprecedented” 3Health News:Bob Seger Presale Tickets: QueenBeeTickets.com Delights Fans with Discounted Tickets for All 20 Stops on Seger’s “Ride Out” Tour with The Silver Bullet Band 2Health News:Immunotherapy could stop resistance to radiotherapy 2
... Kaiser ... medical surge facility at the 2010 Pasadena Marathon in California. , ... Pasadena, CA (Vocus) March 17, 2010 -- Kaiser ... DRASH medical surge facility at the 2010 Pasadena Marathon in California., , , ...
... million more Americans access to health insurance , ... year of fierce partisan debate, the Democrat-controlled House ... $940 billion health-care reform bill, which would extend ... prevent insurance companies from denying coverage to people ...
... the genomes of thousands of "never smokers" diagnosed with lung cancer ... say could be responsible for a significant number of those cancers. ... Lancet Oncology , the researchers reported that about 30 percent ... the same uncommon variant, or allele, residing in a gene known ...
... organization Eagle Forum, made the following remarks after the public announcement that formerly pro-life Democrat Bart Stupak (D-MI) will cast a "yes" vote for the Senate ... ... ... ...
... more Americans access to health insurance , FRIDAY, March ... furiously debated $940 billion health-care reform bill moving toward ... boils down to one simple tenet: More Americans should ... is the coverage of 31 million uninsured individuals, and ...
... 21 Family Research Council President Tony Perkins released the following statement in response to reports that President Obama may issue an executive order regarding government funding of ... ... ... ...
Cached Medicine News:Health News:DRASH Keeps Marathon Runners On Track 2Health News:DRASH Keeps Marathon Runners On Track 3Health News:House Democrats Approve Health-Care Reform Bill 2Health News:House Democrats Approve Health-Care Reform Bill 3Health News:House Democrats Approve Health-Care Reform Bill 4Health News:Gene is linked to lung cancer development in never-smokers 2Health News:Gene is linked to lung cancer development in never-smokers 3Health News:Gene is linked to lung cancer development in never-smokers 4Health News:Schlafly: Health Care Vote Set to Expose the Myth of the 'Pro-Life Democrat' 2Health News:Schlafly: Health Care Vote Set to Expose the Myth of the 'Pro-Life Democrat' 3Health News:Showdown Over Health-Care Reform Bill Nears 2Health News:Showdown Over Health-Care Reform Bill Nears 3Health News:Showdown Over Health-Care Reform Bill Nears 4Health News:Executive Order Will In No Way Prevent Federal Funding of Elective Abortion 2Health News:Executive Order Will In No Way Prevent Federal Funding of Elective Abortion 3Health News:Executive Order Will In No Way Prevent Federal Funding of Elective Abortion 4
... in two tip styles- the ... staggered eyes, and the angled ... catheter valve options, SAFE-T-VAC and ... with virtually no residual vacuum ...
Sterile Single Loop Pediatric Suction Catheters with TOUCH-TROL Valve...
... Our Tri-Flo® suction catheter design ... to your patients while still providing ... pediatric catheters (5/6, 8 or 10 ... facilitate proper catheter placement. Our complete ...
Suction catheter with thumb valve, two eyes, whistle tip...
Medicine Products: