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Merz Pharmaceuticals Joins Patient Advocates to Raise Awareness of Cervical Dystonia and Blepharospasm
Date:4/14/2011

n involuntary contractions in the eyelids which can vary from an increased blink rate and intermittent eyelid spasm to eye closing for most of the day. Blepharospasm usually begins in the fifth to sixth decade of life and is more common in women than in men.

According to an epidemiology study conducted in Rochester, Minn., focal dystonia (which includes cervical dystonia and blepharospasm) is estimated to affect 295 per million people in the U.S.

About XEOMIN® (incobotulinumtoxinA)
XEOMIN is a prescription medicine that is used to treat adults with cervical dystonia to decrease the severity of abnormal head position and neck pain, as well as the abnormal spasm of the eyelids (blepharospasm) in adults who have had prior treatment with onabotulinumtoxinA (Botox®). XEOMIN has been used around the world since 2005 and was introduced to the U.S. market in 2010 by Merz Pharmaceuticals, LLC.

Botulinum toxin is a naturally occurring protein produced by the bacteria Clostridium botulinum. Botulinum toxin type A—the active ingredient in XEOMIN—is produced commercially from C. botulinum serotype A.

XEOMIN is injected into muscles to decrease their activity. XEOMIN blocks the release of a chemical messenger—acetylcholine—that conveys the signal from nerve terminals and causes muscle fibers to contract. Not all terminals are affected by botulinum toxin, so the muscles can still contract, just less forcefully. This allows the muscles to contract more normally.

IMPORTANT SAFETY INFORMATION

XEOMIN® may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems any time (hours to weeks) after treatment with XEOMIN:

  • Problems with swallowing, speaking, or breathing can happen after an injection of XEOMIN if the muscles that you use to brea
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SOURCE Merz Pharmaceuticals, LLC
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