Navigation Links
Merz Pharmaceuticals Announces Results of Three Clinical Trials With NT-201 (Botulinum Neurotoxin Type A Free From Complexing Proteins) in Movement Disorder Patients
Date:4/28/2009

SEATTLE, April 28 /PRNewswire/ -- Results from two prospective, double-blind placebo controlled multi-center studies in patients with cervical dystonia and blepharospasm, and pooled European efficacy and safety data in patients with focal dystonia and upper limb spasticity will be presented at the American Academy of Neurology's (AAN) 61st annual meeting in Seattle. The studies were sponsored by Merz Pharmaceuticals, which plans to file a Biologic License Application (BLA) for NT-201 in the USA in the near future.

"The data to be presented at AAN complement the European data. We now have robust U.S. data for Xeomin (the brand name for NT-201 in Europe) for the symptomatic management of movement disorders," said Eric Pappert, M.D., Vice President of Medical Affairs, Merz Pharmaceuticals, USA.

NT-201 is a botulinum neurotoxin type A free from complexing proteins approved for marketing in Europe since 2007 to treat various movement disorders, and recently approved in Canada for the indications of symptomatic management of blepharospasm, cervical dystonia and post-stroke spasticity of the upper limb. Through advanced manufacturing processes, NT-201 combines high biologic activity with low bacterial protein load, making it a neurotoxin therapy free from complexing proteins. In pre-clinical work, the exposure to complexing proteins has been found to heighten the immune system response to botulinum toxin.

"Xeomin - the proposed brand name for NT-201 -- potentially offers a new option to treat movement disorders. Because Xeomin combines high biologic activity with low protein load, it is a neurotoxin that is free from complexing proteins," said David M. Simpson, M.D., Professor of Neurology and Neuromuscular Diseases at Mount Sinai Medical Center in New Yo
'/>"/>

SOURCE Merz Pharmaceuticals
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. Lexicon Pharmaceuticals Provides Clinical Pipeline Update and Reports 2009 First Quarter Results
2. Affitech-Discovered Anti-PS Antibodies in Development by Peregrine Pharmaceuticals Show Excellent Functionality in Preclinical Studies
3. Ferring Pharmaceuticals Launches Phase IIIB Trial of Degarelix as Intermittent Therapy
4. Addrenex Pharmaceuticals Reports Positive Results in Second Phase 3 Study of ADHD Medication
5. NovaBay(R) Pharmaceuticals Enters into Agreement to Broaden Intellectual Property Estate and Expand Clinical Opportunities for Its Aganocide(R) Compounds
6. Peregrine Pharmaceuticals Reports Positive Preliminary Data From Phase II Bavituximab Lung Cancer Trial
7. Trubion Pharmaceuticals, Inc. Announces Upcoming Presentation at the 2009 American Association of Cancer Research Annual Meeting
8. VentiRx Pharmaceuticals Initiates Phase I Clinical Trial of VTX-1463, a Novel TLR8 Agonist for the Treatment of Allergic Rhinitis
9. Osprey Pharmaceuticals U.S.A., Inc. Initiates Phase Ib Clinical Trial in IgA Nephropathy
10. Optimer Pharmaceuticals Receives Production Patent for Lead Product Candidate Fidaxomicin
11. Raptor Pharmaceuticals Appoints Dr. Patrice P. Rioux as Chief Medical Officer

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/25/2009)...ire-FirstCall/ -- Pharmasset, Inc. (Nasdaq: VRUS ...ed to discovering, developing and commercializing ...nancial results for the fiscal year ended Septembe...$58.4 million in cash, cash equivalents and short ... Highlights ,, RG7128 ,, Phase 2b Trial...
(Date:11/25/2009)...ire/ -- The FDA granted traditional approval for I...ide reverse transcriptase inhibitor (NNRTI). INTEL...use in treatment-experienced adults who are experi...ant to an NNRTI and other antiretroviral (ARV) age... data from two Phase 3 studies known as DUET-1 and...
(Date:11/25/2009)...ewswire/ -- Regado Biosciences, a privately held c...ptamers with active control agents, announced that...enting at the Piper Jaffray 21st Annual Health Car...ork City. Dr. Mazzo,s presentation will be given ...clude an overview of the Company,s pipeline with e...
Breaking Medicine Technology:Pharmasset Reports Fiscal Year End 2009 Financial Results 2Pharmasset Reports Fiscal Year End 2009 Financial Results 3Pharmasset Reports Fiscal Year End 2009 Financial Results 4Pharmasset Reports Fiscal Year End 2009 Financial Results 5Pharmasset Reports Fiscal Year End 2009 Financial Results 6Pharmasset Reports Fiscal Year End 2009 Financial Results 7Pharmasset Reports Fiscal Year End 2009 Financial Results 8Pharmasset Reports Fiscal Year End 2009 Financial Results 9Pharmasset Reports Fiscal Year End 2009 Financial Results 10U.S. Food And Drug Administration (FDA) Grants Traditional Approval for INTELENCE(R) (etravirine) 2U.S. Food And Drug Administration (FDA) Grants Traditional Approval for INTELENCE(R) (etravirine) 3U.S. Food And Drug Administration (FDA) Grants Traditional Approval for INTELENCE(R) (etravirine) 4U.S. Food And Drug Administration (FDA) Grants Traditional Approval for INTELENCE(R) (etravirine) 5Regado Biosciences to Present at the Piper Jaffray 21st Annual Health Care Conference on December 1, 2009 2FRC Calls on President Obama Speaker Pelosi and Senator Reid to Repudiate Diana DeGettes Religious Bigotry 61579 1FRC Calls on President Obama Speaker Pelosi and Senator Reid to Repudiate Diana DeGettes Religious Bigotry 61579 22010 International SPA Association Trend Watch 61576 12010 International SPA Association Trend Watch 61576 22010 International SPA Association Trend Watch 61576 32010 International SPA Association Trend Watch 61576 4IEHP Ranks 232 in California Among Medicaid Health Plans 61573 1IEHP Ranks 232 in California Among Medicaid Health Plans 61573 2
.../PRNewswire-FirstCall/ --,SuperGen, Inc. today ann...r, will present at the C.E. Unterberg, Towbin Emer...July 12, 2007 at the Mandarin,Oriental Hotel in Ne... Unterberg, Towbin Emerging,Growth Opportunities C...A live webcast of the presentation will be availab...
...SWICK, New Jersey, July 03, 2007,/PRNewswire-First...,company, announced today that J. Michael French, ...erberg, Towbin Emerging Growth,Opportunities Confe...Mandarin Oriental Hotel in New York. , A live audi...,the "Investors" section of the company,s website,...
Other Medicine Technology:SuperGen to Present at the C.E. Unterberg, Towbin Emerging Growth,Opportunities Conference 2Rosetta Genomics to Webcast Presentation at CE Unterberg, Towbin,Emerging Growth Opportunities Conference 2
(Date:11/30/2009)...king stuffer that saves lives? Holiday shoppers re...DS® , Pet Collars and Leashes because they ar...hat make a difference. , ... you like to give a gift this holiday season that ... super-reflective POP BANDS® made with 3M,s Sc...
(Date:11/30/2009)... Island courtroom to recreate scene of accident, p...e for client’s accident. , ...- A Staten Island, N.Y. jury awarded a verdict of ...njured at a New York City construction site in 200...tion Company et al (Index No. 102557/05, Cal. No. ...
(Date:11/30/2009)...EETING, Pa., Nov. 30 The Universit...at it has signed an agreement with ECRI Institute&...ic medical center members special pricing on ECRI,...eement will offer UHC members current data to assi...dent nonprofit organization, is a leader in provid...
(Date:11/30/2009)...aled that beverage can pull-tabs were being swallo...cturers to stay-tabs. But a study presented today ...of North America (RSNA) found that the new tabs ar...g factors leading the change in beverage can const...wallowing of the pull-tab and potential related in...
(Date:11/29/2009)...ope show a steady decline in mortality between the...cancers in the European Union (EU) between these t...ercent in women, with a large drop among the middl...e in the cancer journal, Annals of Oncology [1] ... there was an average 185.2 deaths per 100,000 of ...
Breaking Medicine News(10 mins):Health News:Fun and Fashionable Holiday Gifts that Save Lives 2Health News:Fun and Fashionable Holiday Gifts that Save Lives 3Health News:Fun and Fashionable Holiday Gifts that Save Lives 4Health News:Raphaelson & Levine Secures $1.1 Million Verdict for Victim of New York Construction Accident 2Health News:University HealthSystem Consortium and ECRI Institute(R) to Provide Enhanced Health Technology Assessment Services 2Health News:University HealthSystem Consortium and ECRI Institute(R) to Provide Enhanced Health Technology Assessment Services 3Health News:Beverage can stay-tabs pose swallowing risk 2Health News:New figures on cancer in Europe show a steady decline in mortality but big variations 2Health News:New figures on cancer in Europe show a steady decline in mortality but big variations 3Health News:New figures on cancer in Europe show a steady decline in mortality but big variations 4Health News:New figures on cancer in Europe show a steady decline in mortality but big variations 5
...tland has planned to raise its legal age for buyin...Health Ministry said //that the new legislation wo... was planned following the recommendations made by...obacco to minors and introducing negative licensin...
...the Kingdom of Saudi Arabia have taken a decision ...Pakistan regardless //of age and vaccination statu...accine prior to departure for Saudi Arabia. This d...lth & Family Welfare has immediately asked all Sta...
...ennifer Aniston says yoga helped her deal with her...oga she was able to get her mind and body back in ...had "emotions she needed to move" before she comme...yes during yoga and adds, "I was crying through mo...
... unique? Of the many explanations that can be offe...elin.// Conventional wisdom holds that myeli... long fiber that conducts the neuron’s electrical ...or George Bartzokis, M.D., has already shown that ...
...bs the number of pounds women put on as they age, ... led by an Indian-American doctor.// In a study t...s, the team headed by Dr Sanjay Patel of Case West...published in the American Journal of Epidemiology ...
...y shed light on a nagging mystery in neurobiology:...s contain// considerable pools of free zinc ions. ...ubstances that regulate neuronal signaling in the ...a central role for zinc in modulating signaling am...
Other Medicine News:Health News:Blame Myelin for Many Neuropsychiatric Disorders 2Health News:Zinc – A New Key Player In Brain Circuitr 2
...is a rapid, real-time thermal cycler used for iden...By automating much of the testing process, and mak...it is the fastest, easiest to use, and most flexib...ers highly accurate and consistent test results in...
...is a rapid, real-time thermal cycler used for iden...By automating much of the testing process, and mak...it is the fastest, easiest to use, and most flexib...ers highly accurate and consistent test results in...
...is a rapid, real-time thermal cycler used for iden...By automating much of the testing process, and mak...it is the fastest, easiest to use, and most flexib...ers highly accurate and consistent test results in...
...rmal Block and its operation software are optimize...expression, genotyping, counting bacterial/viral l...array results. Exicycler is capable of measuring m...protein-protein and protein-ligand, using fluoresc...
Medicine Products: