Navigation Links
Memory Pharmaceuticals and Roche Expand R3487/MEM 3454 Development Program
Date:9/17/2008

- Amendment Results in Accelerated Payments of $8.5 Million -

MONTVALE, N.J., Sept. 17 /PRNewswire-FirstCall/ -- Memory Pharmaceuticals Corp. (Nasdaq: MEMY) today announced that it has amended its nicotinic alpha-7 receptor agonist agreement with Roche to expand the Phase 2 development program for R3487/MEM 3454 in cognitive impairment associated with schizophrenia (CIAS). Memory Pharmaceuticals is currently conducting a Phase 2 trial of R3487/MEM 3454 in CIAS, and the companies have agreed to expand the study to allow for an increase in the target number of patients enrolled in the trial to up to approximately 212 patients, which will provide for a more robust data set and increase the potential for the study to facilitate advancing the compound into a pivotal trial. In addition, Roche has notified Memory Pharmaceuticals that it intends to initiate a Phase 2 trial of R3487/MEM 3454 in Alzheimer's disease starting either at the end of this year or at the beginning of 2009.

Under the terms of the amendment, Roche will provide funding to Memory Pharmaceuticals, in advance, for all costs associated with the increase in enrollment and will accelerate a portion of the $17.0 million payment associated with the completion of the Phase 2 CIAS trial as follows: $3.5 million in connection with entering into this amendment and $5.0 million upon the completion of enrollment for the CIAS trial. The payment of the remaining $8.5 million will become due 30 days following the availability of top-line data from the Phase 2 CIAS trial, which is now expected in the second quarter of 2009.

"Our CIAS trial is the first major trial evaluating a nicotinic alpha-7 receptor agonist in this indication, and this amendment reflects our joint
'/>"/>

SOURCE Memory Pharmaceuticals Corp.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related medicine technology :

1. Study Suggests a Possible Way to Offset Chemobrain Memory Loss
2. Alzheimers Foundation of America Survey: Americans With Memory Concerns Fall Short of Talking to Doctors
3. Memory Pharmaceuticals Highlights Progress with Key Programs at its R&D Day
4. Roche Exercises its Option to Further Develop and Commercialize Memory Pharmaceuticals Nicotinic Alpha-7 Agonist, MEM 3454
5. Medivations Dimebon(TM) Significantly Improved Thinking and Memory in Alzheimers Disease Patients Over One Year
6. How Big Is Your Brain? Its Size May Protect You from Memory Loss
7. Memory Pharmaceuticals Reports Fourth Quarter and Full Year 2007 Financial Results
8. Memory Pharmaceuticals & Roche Expand Development Program for MEM 3454 in Schizophrenia
9. Experts Call for Widespread Use of Memory Screenings and Emphasize Value of Early Detection of Dementia
10. Memory Pharmaceuticals Announces Results for Phase 2a Trial of MEM 1003 in Alzheimers Disease
11. Memory Pharmaceuticals Commences Phase 1 Clinical Program for R4996/MEM 63908
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... Corporation (NYSE: HAE ) announced today that ... present at The Deutsche Bank 38 th Annual dbAccess ... on May 29, 2013 at 1:30pm Eastern time.  ... may access Mr. Lindop,s presentation live via webcast at: ... (NYSE: HAE ) is a global healthcare company ...
(Date:5/23/2013)... KNOXVILLE, Tenn. , May 23, 2013 /PRNewswire/ ... of 24-hour nurse triage and nurse advice lines, ... 10-person committee, comprising physician, nursing and administrative leaders, ... providing safe, quality and cost-effective services for hospital ... "As our national healthcare system evolves, it,s imperative ...
(Date:5/23/2013)... Mich. , May 23, 2013  Every day, their ... of air to his lungs. April and Bryan ... dire predictions weren,t true. "Quite a few doctors ... hospital alive," says April Gionfriddo , about ... desperate. Anything that would work, we would take it and ...
Breaking Medicine Technology:TeamHealth Medical Call Center Forms Clinical Advisory Committee 2Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 2Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 3Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 4
... 12, 2011 Southern Home Medical Equipment, Inc. ... healthcare professionals and equipment to medical institutions, announced ... operations for fiscal year 2010 have been restated ... Medical Staffing. In a previous announcement ...
... Inc., a privately held medical device company focused on ... announced the initial launch of its Durango™ Stand-Alone ALIF ... was made at the 2011 American Association of Neurological ... The Durango system is intended to treat degenerative disc ...
Cached Medicine Technology:Southern Home Medical Equipment Reports Additional Revenues and Profits for 2010 2Lanx®, Inc. Launches Durango™ Stand-Alone ALIF System 2
(Date:5/24/2013)... Drugs commonly used to treat glaucoma may cause droopy ... vision, according to a new study. The drugs, ... reduce eye pressure, have already been shown to cause ... researchers said, suggesting that the new findings could lead ... be conservative when prescribing these drugs, the researchers added, ...
(Date:5/24/2013)... New York, New York (PRWEB) May 24, 2013 ... naturally white teeth. It is not uncommon for the majority ... natural teeth. Whether it is due to a coffee addiction ... this is why whitening procedures are so popular. ... of a new and very effective whitening system: Venus White ...
(Date:5/24/2013)... May 24, 2013 Area homeowners dreaming about ... new hot tubs to choose from at factory-direct pricing during ... The sales event takes place at Emerald Pool and ... , Jacuzzi, the industry's leading hot tub brand, scheduled ... the country. The event will feature popular hot tub models ...
(Date:5/24/2013)... (PRWEB) May 24, 2013 The nation’s ... involving Intuitive Surgical Inc.’s da Vinci Surgical System concluded ... records, a Washington State Court jury ruled in a ... training a surgeon who performed a da Vinci prostatectomy ... The patient’s family had alleged in their lawsuit that ...
(Date:5/24/2013)... Two mutations central to the development of infantile myofibromatosis ... bone, and soft tissuemay provide new therapeutic targets, according ... Mount Sinai. The findings, published in the American ... treatment options for this debilitating disease, for which the ... the tumors. , IM is an inheritied disorder that ...
Breaking Medicine News(10 mins):Health News:Common Glaucoma Drug May Cause Droopy Eyelids, Study Finds 2Health News:Herald Square Dental Introduces New In-office Whitening System: Venus White Max 2Health News:Truckload of Jacuzzi® Hot Tubs Rolls into Bend, Oregon on May 24, 2013 for Sales Event 2Health News:Da Vinci Robot Lawsuit News: Bernstein Liebhard LLP Comments on Verdict in Nation’s First Trial Involving Alleged Da Vinci Complications 2Health News:Da Vinci Robot Lawsuit News: Bernstein Liebhard LLP Comments on Verdict in Nation’s First Trial Involving Alleged Da Vinci Complications 3Health News:Researchers identify first drug targets in childhood genetic tumor disorder 2
... but are prepared to try and lessen the number of ... studying healthcare literature, a team of Cochrane Researchers could find ... of cutting down the number of cigarettes. ,The ... helping them to stop smoking completely. But, little thought has ...
... it doesnt come cheap. But the new bionic hand, developed by a ... , ,It can't click its fingers or play the ... ,It can, for instance, turn a key in a lock, hold ... , ,David Gow who works with with Lothian NHS in ...
... Researchers have revealed that combining a non-pyrethroid insecticide, ... to be an effective insecticide-repellent synergy against ... ,A combination of the two had proved ... addition of their respective properties. Mosquito nets soaked ...
... a 10 million dollar specialist cancer hospital which will enable ... . ,Mwanawasa said the National Cancer Diseases Hospital ... cancer patients in Zambia who have previously had to be ... average 10,000 dollars per person. ,"Treatment at the ...
... with the U.K.-based Oxford Brookes University, has opened a ... ,For the people of the city that subsist ... development. For now scientific testing methodology is generating enough ... which food is converted into blood glucose) to prompt ...
... the premier institute of medicine AIIMS and has been asked ... State Consumer Commission . ,All India Institute of Medical ... cancer patient and removing her breast as a part of ... by Justice J D Kapoor held the hospital guilty of ...
Cached Medicine News:Health News:Chain Smokers Prepared to Lessen Their Daily Cigs Rather Than Quitting 2Health News:Scottish Engineer Devises Versatile Hand 2Health News:Insecticide and Repellent Combo Effective in Eliminating Malarial Mosquitoes 2Health News:A Centre for Glycemic Index Testing Opened in Chennai 2Health News:AIIMS Fined Rs 5 Lakhs for Negligence 2
... is made of two probes which are ... sensor distance., ,VersaFlex disposable catheters for ... VersaFlex catheters are the smallest diameter esophageal ... are the perfect combination of flexibility and ...
... Slimline multi-use catheters are designed ... solution with the following benefits:, ... reference: ,In procedures where the multi-use ... Gel creates stable contact to the ...
FLEXILOG accessory....
FLEXILOG spare part....
Medicine Products: