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Medivir Notes That Partner Tibotec Announced Week 24 Interim Results From Phase 2b TMC435 PILLAR Study to be Presented as a Late-Breaker at AASLD
Date:11/1/2010

HUDDINGE, Sweden, November 1, 2010 /PRNewswire/ -- Medivir AB (OMX:MVIR), the research-based speciality pharmaceutical company focused on the development of high-value treatments for infectious diseases, notes that its development partner, Tibotec Pharmaceuticals, has announced the results of a Week-24 planned interim analysis of the Phase 2 response-guided PILLAR study for TMC435, Medivir's key pipeline asset, a hepatitis C protease inhibitor dosed once-daily. The study was conducted in treatment-naive patients with chronic genotype 1 Hepatitis C virus (HCV) and is part of a late-breaker oral presentation at the 61st Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) in Boston, MA., USA.

Highlights of the data: - 79% to 86% of patients were able to stop all therapy at week-24 - No relevant differences for adverse events between TMC435 treatment groups and placebo

Commenting on the announcement by Medivir's development partner, Tibotec, Ron Long, Chief Executive of Medivir, said: "We are very pleased to have such exciting TMC435 data presented by our partner, Tibotec, at the AASLD. The data announced shows the significant impact that TMC435 could have on the way we treat hepatitis C."

Please note that Medivir will be hosting meetings for Investors, Analysts and the Media at the AASLD (see end of press release).

Tibotec released the following statement on the results on Saturday 30th October:

Week 24 interim results from phase 2b PILLAR study to be presented as late-breaker at AASLD

-- Data show high antiviral activity, safety and tolerability comparable to placebo

Boston, MA. Saturday 30th October 2010 - Tibotec Pharmaceuticals (Tibotec) today will present the results of a Week-24 planned interim analysis of the phase 2 response-guided PILLAR study in treatment-naive patients with chronic genotype 1 hepatitis C virus (HCV) as part of a late-breaker oral presentation at the
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SOURCE Medivir
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