Navigation Links
Medivation Initiates Second Pivotal Phase 3 Trial of Dimebon(TM) in Patients With Alzheimer's Disease
Date:6/9/2008

each of the five primary aspects of the disease -- memory, thinking, activities of daily living, behavior and overall clinical function. Significant gains over placebo were evident after as little as 12 weeks of treatment, and were maintained after both six months and a full year of treatment. Importantly, overall benefit compared to placebo continued to increase over time, and was larger at one year than at six months. Dimebon was well-tolerated throughout the entire one-year treatment period. The majority of adverse events were mild. Dry mouth (18.0 percent Dimebon, 1.1 percent placebo) and depressed mood were the most common events. Patients treated with Dimebon experienced significantly fewer serious adverse events than those treated with placebo at one year.

About Dimebon

Dimebon is an orally-available small molecule that has been shown to inhibit brain cell death in preclinical models relevant to Alzheimer's disease and Huntington's disease, making it a potential treatment for these and other neurodegenerative diseases. Preclinical data generated to date suggest that Dimebon operates through a novel mitochondrial mechanism of action.

Medivation is also evaluating Dimebon in an ongoing Phase 2 clinical trial in Huntington's disease.

About Medivation

Medivation, Inc. is a biopharmaceutical company focused on the rapid development of novel small molecule drugs to treat serious diseases of the central nervous system and cancers for which there are limited treatment options. Medivation aims to revolutionize the treatment of these diseases and offer hope to critically ill patients and their caregivers. The Company's current clinical development program includes a pivotal and confirmatory Phase 3 trial of Dimebon(TM) in Alzheimer's disease, a Phase 2 clinical trial of Dimebon in patients with Huntington's disease, and a Phase 1-2 clinical trial of MDV3100 in patients with castration-resistant (also known as hormone-refractory) prost
'/>"/>

SOURCE Medivation, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Medivation Announces Presentation of Positive MDV3100 Clinical Data in Castration-Resistant Prostate Cancer Patients at 44th ASCO Annual Meeting
2. Medivation Announces Presentation of MDV3100 Clinical Data in Patients With Castration-Resistant Prostate Cancer at 44th American Society of Clinical Oncology Annual Meeting
3. Medivations Dimebon(TM) Significantly Improved Thinking and Memory in Alzheimers Disease Patients Over One Year
4. Medivations Dimebon(TM) Significantly Improved Daily Function in Alzheimers Disease Patients, Resulting in Reduced Need for Caregiver Assistance
5. Medivations Dimebon(TM) Stabilizes Behavioral Symptoms in Alzheimers Disease Patients, Resulting in Reduced Caregiver Distress
6. Medivations MDV3100 Demonstrates Substantial PSA Reductions in First Patient Groups Treated in Phase 1-2 Hormone Refractory Prostate Cancer Trial
7. TorreyPines Therapeutics Initiates Clinical Trial to Evaluate Analgesic Effect of Oral Prodrug of Tezampanel
8. Nuvelo Initiates Phase 1B Clinical Trial of Anticoagulant NU172
9. Anadys Pharmaceuticals Initiates Phase I Clinical Trial of ANA598
10. Wyeth Initiates INTORACT -- A New Clinical Trial to Examine TORISEL Plus Avastin for First-Line Treatment of Advanced Kidney Cancer
11. Human Genome Sciences Initiates First Clinical Trial of Lead IAP Inhibitor HGS1029 in Advanced Solid Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... 22, 2014 /CNW/ - On Aug. 20, at its ... Canadian Medical Association (CMA) voted on and approved a ... including medicinal cannabis. Bedrocan Cannabis Corp., a leading Canadian ... CMA motion. The CMA is quite right ... with smoking any plant material, including medicinal cannabis. While ...
(Date:8/22/2014)... -- MC Medical, a subsidiary of Mitsubishi Corporation (MCM), and ... medical device company, have formally agreed to an ... system in Japan . It is anticipated ... Japan in the latter half of 2015. ... portfolio in endoscopic surgery market in Japan ...
(Date:8/22/2014)... DUBLIN , Aug. 22, 2014 ... the "Global and Chinese Particulate Respirators Industry Report ... The Global and Chinese Particulate Respirators Industry Report 2014 ... state of the global particulate respirators industry with a ... a basic overview of the industry including definitions, classifications, ...
Breaking Medicine Technology:Bedrocan Canada Statement Regarding Canadian Medical Association Motion on Smoking Marijuana 2MC Medical agrees to be the exclusive distributor of FloShield products in Japan 2Global and Chinese Particulate Respirators Industry Report 2014 2
... WASHINGTON, Sept. 15 A home medical equipment provider ... "competitive" bidding program for durable medical equipment and services. ... and wound care specialist at Allcare Medical, in Sayreville, ... on Health that the bidding program, as designed by ...
... Angioslide Commercializes in the U.S. First Device to Combine Balloon Angioplasty and... -- MINNEAPOLIS, Minnesota, September 15, ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... BitlyCB.alertResponse = function(data) { var s = ,; var first_result; // Results are keyed by longUrl, so ...
Cached Medicine Technology:Homecare Provider Testifies on Downside of Medicare 'Competitive' Bidding Program Before House Energy and Commerce Subcommittee 2Homecare Provider Testifies on Downside of Medicare 'Competitive' Bidding Program Before House Energy and Commerce Subcommittee 3Homecare Provider Testifies on Downside of Medicare 'Competitive' Bidding Program Before House Energy and Commerce Subcommittee 4Homecare Provider Testifies on Downside of Medicare 'Competitive' Bidding Program Before House Energy and Commerce Subcommittee 5Homecare Provider Testifies on Downside of Medicare 'Competitive' Bidding Program Before House Energy and Commerce Subcommittee 6Homecare Provider Testifies on Downside of Medicare 'Competitive' Bidding Program Before House Energy and Commerce Subcommittee 7Angioslide Commercializes in the U.S. First Device to Combine Balloon Angioplasty and Embolic Capture 2Angioslide Commercializes in the U.S. First Device to Combine Balloon Angioplasty and Embolic Capture 3Angioslide Commercializes in the U.S. First Device to Combine Balloon Angioplasty and Embolic Capture 4Angioslide Commercializes in the U.S. First Device to Combine Balloon Angioplasty and Embolic Capture 5Angioslide Commercializes in the U.S. First Device to Combine Balloon Angioplasty and Embolic Capture 6Angioslide Commercializes in the U.S. First Device to Combine Balloon Angioplasty and Embolic Capture 7Angioslide Commercializes in the U.S. First Device to Combine Balloon Angioplasty and Embolic Capture 8
(Date:8/23/2014)... New York, New York (PRWEB) August 23, 2014 ... ( http://www.consumerinjurylawyers.com/wright-conserve-hip-replacement.html ) filed on behalf of ... in the Conserve hip replacement line continue to ... District of Georgia, Bernstein Liebhard LLP reports. According ... has established a bellwether trial program that would ...
(Date:8/23/2014)... Boston, MA (PRWEB) August 23, 2014 ... now have a study aid in preparing for Food ... safety practice test by Dynamic Path. , Dynamic ... study module, which includes more than 200 review questions ... study materials are designed to cover requirements of the ...
(Date:8/23/2014)... Teen drug and alcohol abuse is a ... Wilmington, NC. Substance abuse can happen to people of ... and alcohol dependency in higher numbers than ever before. ... abuse, but don’t know where to find professional youth ... a challenge because most treatment options are designed for ...
(Date:8/22/2014)... August 23, 2014 2014 Deep ... a professional and in-depth research report on the ... Meter information, including Glucose Meter definition, classification, application, ... overview. This research covers the international market analysis, ... analysis covering macroeconomic environment & economic situation analysis. ...
(Date:8/22/2014)... Top 10 Best SEO Hosting (Top10BestSEOHosting.com) has recently ... recommended FatCow ( http://www.top10bestseohosting.com/go/FatCow.com/ ) and BlueHost to ... Best SEO Hosting states, “It is hard to ... these companies have outperformed their competitors on hosting ... can get the best web hosting at affordable ...
Breaking Medicine News(10 mins):Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 2Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 3Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 4Health News:Food Handler Safety Certification Made Easy with Dynamic Path 2Health News:Troubled Teens Wilmington Helpline Guides Adolescents to the Path of Recovery 2Health News:Glucose Meter Industry Global (Europe, Asia, NA, ROW) Analysis Now Available at ReportsnReports.com 2Health News:Glucose Meter Industry Global (Europe, Asia, NA, ROW) Analysis Now Available at ReportsnReports.com 3Health News:FatCow Reviews Released by Top10BestSEOHosting.com 2
... Pay Copay Inspired Members to ... More Strongly Embrace Generics, PHILADELPHIA, Dec. 12 ... more people are learning about the effectiveness,safety and cost saving benefits ... by Independence Blue Cross (IBC). Three-quarters,of the IBC members surveyed believe ...
... organizations and Babies "R" Us to help prepare local moms for ... ... Ind., Dec. 12 With a traditional theme of,pink and blue, ... and Blue Shield hosts a community-wide baby shower today,for local moms-to-be ...
... DD ),has appointed Phuong Tram Chief Information Officer (CIO), ... DuPont Information Technology,(IT) Integrated Service Delivery, Tram, 53, ... retire Dec.,31 after 39 years of service with DuPont., ... a variety of business and,functional management positions in Australia ...
... reach their target levels, survey finds , , WEDNESDAY, Dec. ... adults with conditions that increase their risk for cardiovascular ... of a University of California, Irvine study that looked ... a national health survey. , Overall, 1,671 (31.4 ...
... but somebody,s got to do it. Hair Fairies - The Head Lice, ... first and only ... Chicago., CHICAGO, Dec. 12 No two words in the English ... camps, day care centers, and other kid-centric services are often,sent into crisis ...
... in control of their health; Gives, health plans and employers a ... ... N.C., Dec. 12 Medcryption, Inc. today announced,a major update to VitalChart, ... health, For consumers, VitalChart offers a secure, convenient way to access ...
Cached Medicine News:Health News:Generic Prescription Drugs Show Increasingly Greater Use in Southeastern Pennsylvania 2Health News:Generic Prescription Drugs Show Increasingly Greater Use in Southeastern Pennsylvania 3Health News:Generic Prescription Drugs Show Increasingly Greater Use in Southeastern Pennsylvania 4Health News:Anthem Blue Cross and Blue Shield Celebrates Local Moms-to-Be at Community Baby Shower 2Health News:Anthem Blue Cross and Blue Shield Celebrates Local Moms-to-Be at Community Baby Shower 3Health News:High Blood Pressure Key Factor for Cardiovascular Disease 2Health News:Head Lice Removal Service Opens in Chicago 2Health News:Head Lice Removal Service Opens in Chicago 3Health News:VitalChart Launches Free Personal Health Record with Rewards System 2
... HPLC system designed to provide fast and ... aid in the comprehensive identification and quantitation ... glycemic control., ,The A1c assay combines the ... accuracy of boronate affinity columns. The result ...
... fastest blood gas analyzers for ... on the market. Equally suitable ... testing. The Roche COMPACT ... reliable assessment of acid-base status ...
... sets the standard for testing blood ... at your patient's side - the ... self contained system can easily be ... ICU, or wherever you need it ...
Flatbed Agitator....
Medicine Products: