Navigation Links
Medivation Announces Publication in The Lancet of Dimebon Pivotal Trial Results in Alzheimer's Disease
Date:7/17/2008

the Alzheimer's Disease and Memory Disorders Center, Baylor College of Medicine in Houston. "There is a clear need for new treatments that can add value and enduring benefit to the treatment of Alzheimer's disease. The results of this trial suggest that, if the findings are replicated, Dimebon could advance Alzheimer's treatment, offering more hope for patients and their caregivers."

Dimebon was well-tolerated throughout the trial. There was no difference between the Dimebon and placebo groups in the number of patients with adverse events, and the most common side effects seen were dry mouth (18 percent versus 1 percent for placebo) and depressed mood/depression (15 percent versus 5 percent for placebo). Importantly, fewer patients treated with Dimebon had serious adverse events than did patients on placebo at the end of the study (3 percent versus 12 percent; p=0.03).

Additional analyses of the Dimebon pivotal study data presented at recent medical conferences showed that Dimebon's impact extended to caregivers. Behavioral improvements in Dimebon-treated patients resulted in a significant decrease in caregiver distress at six months and at one year compared to the distress of caregivers of placebo-treated patients. Further, after six months, caregivers of Dimebon-treated patients saved approximately one hour per day assisting patients with activities of daily living compared to caregivers of placebo-treated patients.

"The magnitude, consistency and duration of the beneficial effects of Dimebon demonstrated in this trial are striking," said Paul Aisen, M.D., Director, Alzheimer's Disease Cooperative Study (ADCS) and Professor in the Department of Neurosciences, University of California, San Diego (UCSD). "In addition, the drug has been well-tolerated to date and, if the safety profile is replicated in the ongoing international trial, it will be a substantial advance for this patient population prone to drug side effects."

"We are pleased
'/>"/>

SOURCE Medivation, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Medivation Announces Positive Top-Line Results From Phase 2 Dimebon Study in Huntingtons Disease
2. Medivation to Host Conference Call at 5 p.m. EDT Monday to Discuss Top-Line Phase 2 Study Results in Huntingtons Disease
3. Medivation Initiates Second Pivotal Phase 3 Trial of Dimebon(TM) in Patients With Alzheimers Disease
4. Medivation Announces Presentation of Positive MDV3100 Clinical Data in Castration-Resistant Prostate Cancer Patients at 44th ASCO Annual Meeting
5. Medivation Announces Presentation of MDV3100 Clinical Data in Patients With Castration-Resistant Prostate Cancer at 44th American Society of Clinical Oncology Annual Meeting
6. Medivations Dimebon(TM) Significantly Improved Thinking and Memory in Alzheimers Disease Patients Over One Year
7. Medivations Dimebon(TM) Significantly Improved Daily Function in Alzheimers Disease Patients, Resulting in Reduced Need for Caregiver Assistance
8. Medivations Dimebon(TM) Stabilizes Behavioral Symptoms in Alzheimers Disease Patients, Resulting in Reduced Caregiver Distress
9. Medivations MDV3100 Demonstrates Substantial PSA Reductions in First Patient Groups Treated in Phase 1-2 Hormone Refractory Prostate Cancer Trial
10. Vical Announces Breakthrough for Pandemic Influenza DNA Vaccines With Preliminary Human Data
11. Biodel Inc. Announces the Completion of Its Two Pivotal Trials and the Release of EASD Abstracts Containing Additional Interim Data From Its VIAject(TM) Program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... NEW YORK , Aug. 28, 2014 ... market research report is available in its ... Market Forecast 2014-2024 ... Needle-free delivery – discover technological and commercial ... the needle-free delivery market? Visiongain,s brand new ...
(Date:8/28/2014)... , Aug. 28, 2014 Pharmatech initiated ... investment into this game-changing method for matching cancer ... Today, clinical trials target specific cancers, disease staging, ... factors for the cancer, in the first place. ... this information may not be well known to ...
(Date:8/28/2014)... 2014 Tianyin Pharmaceutical Co., Inc. (NYSE ... that specializes in patented biopharmaceutical, modernized traditional Chinese ... (API) today updates the timeline for the GMP ... The Company is scheduled to submit ... Food & Drug Administration,s (CFDA) review in the ...
Breaking Medicine Technology:Needle-Free Delivery: Technology and Market Forecast 2014-2024 2Needle-Free Delivery: Technology and Market Forecast 2014-2024 3Needle-Free Delivery: Technology and Market Forecast 2014-2024 4Needle-Free Delivery: Technology and Market Forecast 2014-2024 5Needle-Free Delivery: Technology and Market Forecast 2014-2024 6Needle-Free Delivery: Technology and Market Forecast 2014-2024 7Needle-Free Delivery: Technology and Market Forecast 2014-2024 8Needle-Free Delivery: Technology and Market Forecast 2014-2024 9Needle-Free Delivery: Technology and Market Forecast 2014-2024 10Needle-Free Delivery: Technology and Market Forecast 2014-2024 11Needle-Free Delivery: Technology and Market Forecast 2014-2024 12Needle-Free Delivery: Technology and Market Forecast 2014-2024 13Needle-Free Delivery: Technology and Market Forecast 2014-2024 14Needle-Free Delivery: Technology and Market Forecast 2014-2024 15Needle-Free Delivery: Technology and Market Forecast 2014-2024 16Needle-Free Delivery: Technology and Market Forecast 2014-2024 17Needle-Free Delivery: Technology and Market Forecast 2014-2024 18Enrollment in Pharmatech's Revolutionary AccessPPM Program Launches 2TPI Submits Dataset for GMP Inspection at Qionglai Facility (QLF) 2
(Date:8/28/2014)... 2014 Recently, iFitDress.com, the distinguished wedding ... of chic bridesmaid dresses . Included in the ... addition, all of them are provided at deeply discounted ... insists on offering fast and reliable delivery service. All ... order in a short time. As is commonly noted, ...
(Date:8/28/2014)... Recently, iFitDress.com, the popular online supplier of wedding dresses ... range of fashionable bridesmaid dresses . Along with that, ... are offered with big discounts, from 15 to 65 percent ... 16. , The company’s experienced workers never compromise on ... all its products are trendy and graceful. , “We are ...
(Date:8/28/2014)... FL (PRWEB) August 28, 2014 Millennium Treatment ... in America is extremely large, and Millennium Treatment Group is ... and treatment that they need. , According to the ... more than 21 million Americans could have benefited from treatment ... those people received help. This means that there is a ...
(Date:8/28/2014)... TN (PRWEB) August 28, 2014 American ... insurance industry on the Internet will now have a ... Pros company. In one click this year, some of ... at http://quotespros.com/life-insurance.html . , The promoted plans ... Quotes Pros finder tool represent popular policies. The term, ...
(Date:8/28/2014)... As the federal government plans its exit strategy from ... rethink its role in providing health care to veterans, says ... Medicine . , "To simply go on doing more of ... the Veterans Health Administration,s cost and population structure pose in ... for Health Policy & Clinical Practice, and David Auerbach, from ...
Breaking Medicine News(10 mins):Health News:New Selection of Chic Bridesmaid Dresses Available at iFitDress.com 2Health News:Fashionable Bridesmaid Dresses for Autumn 2014 from iFitDress.com 2Health News:Millennium Treatment Group Works to Close Treatment Gap 2Health News:Best Life Insurance Rates for 2014 Now Promoted at Insurer Website 2Health News:A VA exit strategy 2
... 2008 Barr,Pharmaceuticals, Inc. (NYSE: BRL ) today ... 8:30AM Eastern time on Thursday, May 8 to discuss,earnings ... March 31,2008. The number to call from within the ... replay of the conference call will be,available from 10:30AM ...
... 7, 2008 Edmond Medical Center and,ophthalmologists M. Andrew ... Eye Associates, will once again participate in the Mission,Cataract ... those who cannot afford to pay., Appointments can ... If the patient qualifies for the cataract surgery and ...
... to increased risk of falls in the elderly can ... the Electronic Health Record, new Geisinger research shows. ... a persons neurochemistry and may predispose elderly patients to ... death in the elderly. , Geisinger pharmacists and geriatricians ...
... Foster Career School,now offers allied health certificate programs ... offerings include a variety of,online certificate programs such ... broad overview of the human body is ideal ... medical transcriptionists, and,first aid technicians can learn the ...
... Stiefel Laboratories,Inc., the world,s largest independent pharmaceutical company ... has been,promoted to the newly created position of ... chief scientific officer will reinforce the,already critical role ... between,all R&D departments. It also will further strengthen ...
... may not only play a central role in the ... also in much more common acquired chronic lung diseases ... chronic obstructive pulmonary disease (COPD). This is the conclusion ... direction of Assistant Professor Dr. Marcus Mall from the ...
Cached Medicine News:Health News:Barr Will Host An Earnings Conference Call on May 8, 2008 to Discuss the Results for the First Quarter of Calendar 2008 2Health News:Barr Will Host An Earnings Conference Call on May 8, 2008 to Discuss the Results for the First Quarter of Calendar 2008 3Health News:Edmond Medical Center to Provide Free Cataract Surgeries 2Health News:Penn Foster Career School Offers Certificate Programs 2Health News:Stiefel Laboratories Appoints First Chief Scientific Officer 2Health News:Stiefel Laboratories Appoints First Chief Scientific Officer 3Health News:Asthma and smoker's lung: dry airways play a key role 2Health News:Asthma and smoker's lung: dry airways play a key role 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: