Navigation Links
Medivation Announces Publication in The Lancet of Dimebon Pivotal Trial Results in Alzheimer's Disease
Date:7/17/2008

- Dimebon Improved the Clinical Course of Alzheimer's Disease; Patients Experienced Statistically Significant Improvements in Memory and Thinking,

Activities of Daily Living, Behavior and Overall Function -

SAN FRANCISCO, July 17 /PRNewswire-FirstCall/ -- Medivation, Inc. (Nasdaq: MDVN) today announced publication of the results of its first Alzheimer's disease pivotal clinical trial of the investigational drug Dimebon in the July 19, 2008 issue of The Lancet. In this double-blind, placebo-controlled trial, patients with mild-to-moderate Alzheimer's disease treated with Dimebon experienced statistically significant improvements compared to placebo in all the key aspects of the disease: memory and thinking, activities of daily living, behavior and overall function.

After both six months and a full year of treatment, Dimebon-treated patients were significantly better than placebo-treated patients on all key aspects of the disease. The benefit on the primary endpoint, the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) at six months, was highly significant (p<0.0001). Patients treated with Dimebon were also significantly improved at six months over baseline on all measures (p=0.005 on ADAS-cog). Dimebon's benefit over placebo continued to increase throughout the 12-month treatment period. At the end of 12 months, Dimebon-treated patients preserved their starting level of function on each measure of Alzheimer's disease.

"In this study, Dimebon improved the clinical course of Alzheimer's disease, which is important given that the natural course is progressive deterioration over time," said Rachelle Doody, M.D., Ph.D., lead author and the Effie Marie Cain Chair in Alzheimer's Disease Research at
'/>"/>

SOURCE Medivation, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Medivation Announces Positive Top-Line Results From Phase 2 Dimebon Study in Huntingtons Disease
2. Medivation to Host Conference Call at 5 p.m. EDT Monday to Discuss Top-Line Phase 2 Study Results in Huntingtons Disease
3. Medivation Initiates Second Pivotal Phase 3 Trial of Dimebon(TM) in Patients With Alzheimers Disease
4. Medivation Announces Presentation of Positive MDV3100 Clinical Data in Castration-Resistant Prostate Cancer Patients at 44th ASCO Annual Meeting
5. Medivation Announces Presentation of MDV3100 Clinical Data in Patients With Castration-Resistant Prostate Cancer at 44th American Society of Clinical Oncology Annual Meeting
6. Medivations Dimebon(TM) Significantly Improved Thinking and Memory in Alzheimers Disease Patients Over One Year
7. Medivations Dimebon(TM) Significantly Improved Daily Function in Alzheimers Disease Patients, Resulting in Reduced Need for Caregiver Assistance
8. Medivations Dimebon(TM) Stabilizes Behavioral Symptoms in Alzheimers Disease Patients, Resulting in Reduced Caregiver Distress
9. Medivations MDV3100 Demonstrates Substantial PSA Reductions in First Patient Groups Treated in Phase 1-2 Hormone Refractory Prostate Cancer Trial
10. Vical Announces Breakthrough for Pandemic Influenza DNA Vaccines With Preliminary Human Data
11. Biodel Inc. Announces the Completion of Its Two Pivotal Trials and the Release of EASD Abstracts Containing Additional Interim Data From Its VIAject(TM) Program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... CHENGDU, China , Dec. 23, 2014 /PRNewswire/ ... a pharmaceutical company that specializes in patented biopharmaceutical, ... active pharmaceutical ingredients (API) today announced that the ... for its Good Manufacturing Practice (GMP) certificate of ... & Drug Administration,s (CFDA). The public notice period ...
(Date:12/22/2014)... , Dec. 22, 2014 NxStage ... manufacturer of innovative dialysis products, announced today that ... cleared its System One™ to perform hemodialysis overnight ... as home nocturnal hemodialysis. NxStage,s® System One is ... the FDA for this indication. ...
(Date:12/22/2014)... Dec. 22, 2014  ConvaTec, a privately-held medical products ... been appointed Interim Chief Executive Officer of the company, ... Ken Berger .  "The Board of Directors of ... ConvaTec over the past three years," said Magnus ... "We are confident that the company is well positioned ...
Breaking Medicine Technology:TPI QLF Achieved Public Notice Status of GMP Certification 2TPI QLF Achieved Public Notice Status of GMP Certification 3NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 2NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 3ConvaTec Names Paul Moraviec Interim CEO Effective December 22, 2014 2
... FRISCO, Texas, Oct. 21 Assured Pharmacy (Pink Sheets: ... medications to more than 3,000 sufferers of chronic pain, announced ... month of September 2010 were $1,391,331 which equates to $66,253 ... when compared with total sales of $1,226,245 for September 2009 ...
... announces that a new market research report is available in ... 2010 http://www.reportlinker.com/p0316666/Japanese-Market-for-Urological-Devices-2010.html By ... nearly triple in value. This report analyzes the markets for ... - Prostate cancer - Urinary incontinence ...
Cached Medicine Technology:Assured Pharmacy Reports Same Store Sales for the Month of September 2010 2Reportlinker Adds Japanese Market for Urological Devices 2010 2Reportlinker Adds Japanese Market for Urological Devices 2010 3Reportlinker Adds Japanese Market for Urological Devices 2010 4Reportlinker Adds Japanese Market for Urological Devices 2010 5Reportlinker Adds Japanese Market for Urological Devices 2010 6Reportlinker Adds Japanese Market for Urological Devices 2010 7Reportlinker Adds Japanese Market for Urological Devices 2010 8Reportlinker Adds Japanese Market for Urological Devices 2010 9Reportlinker Adds Japanese Market for Urological Devices 2010 10Reportlinker Adds Japanese Market for Urological Devices 2010 11Reportlinker Adds Japanese Market for Urological Devices 2010 12Reportlinker Adds Japanese Market for Urological Devices 2010 13Reportlinker Adds Japanese Market for Urological Devices 2010 14Reportlinker Adds Japanese Market for Urological Devices 2010 15Reportlinker Adds Japanese Market for Urological Devices 2010 16
(Date:12/25/2014)... BambooFlooringChina.com sells many bamboo products and the business is ... company announces big discounts on its bamboo mats , ... is the world’s leader in bamboo flooring. According to ... 20, 2015. , The bamboo mats are made from ... All the bamboo strips for the mats are boiled ...
(Date:12/25/2014)... 2014 Recently, LunaDress.co.uk has updated its blog to ... accessories. Now, all of the models at LunaDress.co.uk come with big ... lifts the wedding veil can turn out to be a most ... wedding veil can always bring surprise to a wedding. On the ... to choose veils for a big day . , Going ...
(Date:12/25/2014)... (HealthDay News) -- Overeating is common during the holidays, but ... an expert says. "Don,t arrive at a party hungry. ... know you,ll be attending a party, but deprivation leads to ... at Northern Westchester Hospital in Mount Kisco, N.Y., said in ... during the day and even to have a snack before ...
(Date:12/25/2014)... AngelWeddingDress.com tries its best to translate the experience ... business has introduced its new collection of 2015 prom ... The new prom outfits are guaranteed to contain the ... are specially designed for 2015. Anyone who wants to ... its website before Jan. 26, 2015, the deadline of ...
(Date:12/25/2014)... Viejo, California (PRWEB) December 25, 2014 ... release of ProFire 5k. A fully customizable business presentation ... . , “Adding the ProFire 5k business tool, users ... Said Christina Austin, CEO of Pixel Film Studios. “ProFire ... look and style to add professionalism to a presentation” ...
Breaking Medicine News(10 mins):Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2Health News:LunaDress Provides Professional Tips On Shopping Wedding And Prom Dresses 2Health News:Angelweddingdress 2015 Prom Dresses Online Now 2Health News:Announcing a new ProFire 5k plugin from Pixel Film Studios for Final Cut Pro X Professionals 2
... cardiovascular disease increase dramatically in Australian winters because many ... cold, a Queensland University of Technology seasonal researcher has ... of Health and Biomedical Innovation) said the numbers showed ... health than winters in cold northern European countries such ...
... outside reduced falls among active, ,outdoorsy, elders, study says ... might avoid falls if they take off their bifocal ... and rely on single-vision lenses instead, a new study ... difficulty seeing things at close range, even if they ...
... Electronic Payment Exchange ... a means of securing credit card and ACH transaction data. , ... Wilmington, DE (Vocus) May 26, 2010 -- Electronic Payment ... as a means of securing credit card and ACH transaction data. , , , , ...
... ... DSPanel today announced the availability of their latest product ... announced the availability of DSPanel Performance Canvas 2.2 with Planning, the ... to be used as an accompaniment to Sharepoint 2010 and SQL ...
... ... Cities area can now learn more about the plumbing services that this leading Hermosa ... as get updates on plumbing specials and coupons. , ... (PRWEB) May 26, 2010 -- George Carter of ...
... have used a magnetic resonance imaging (MRI) technique called ... flow patterns in schizophrenic patients quickly and without using ... online edition and July printed issue of the journal ... powerful technique that can help reduce the cost and ...
Cached Medicine News:Health News:Killed by cold: Heart and stroke deaths peak in winter 2Health News:Eyeglass Change Might Keep Elderly From Falling 2Health News:Electronic Payment Exchange Enters its Tenth Year of Issuing Tokens for Securing Credit Card and ACH Transaction Data 2Health News:Electronic Payment Exchange Enters its Tenth Year of Issuing Tokens for Securing Credit Card and ACH Transaction Data 3Health News:DSPanel's New Mobile Analytics Server for Business Intelligence: Data Analysis, Monitoring and Planning When and Where You Need It 2Health News:DSPanel's New Mobile Analytics Server for Business Intelligence: Data Analysis, Monitoring and Planning When and Where You Need It 3Health News:George Carter of Carter's Plumbing & Rooter Announces the Launch of His New Website, CartersPlumbingRedondoBeach.com 2Health News:Blood flows differently through the brains of schizophrenic patients 2
... advanced motorized inverted microscope from Olympus. , ... provides 9 access ports for multiple input ... can have simultaneous access to a primary ... 6-position nosepiece and light path selector, the ...
... Designed to provide exceptional performance ... SteREO Lumar has unrivaled fluorescence ... light microscopy instruments. Developed for ... SteREO Lumar offers first-class optical ...
... TIRF slider, which allows laser coupling via ... for observing rapid membrane processes even ... times extremely short. The easy ... and the effective laser safety equipment of ...
... The MicroFire is a 2-megapixel, 12-bit FireWire digital camera. ... be acquired effortlessly. Imaging has never been this easy! ... CCD - 2/3" Color ... Time - 500 microseconds - 60 seconds ...
Medicine Products: