Navigation Links
Medivation Announces Positive Top-Line Results From Phase 2 Dimebon Study in Huntington's Disease
Date:7/7/2008

g," said Lynn Seely, M.D., chief medical officer of Medivation. "These data are also important because they provide further support for our belief that Dimebon is exerting its benefits through a novel mechanism of action targeting mitochondrial dysfunction, a contributor to the loss of neuronal function in Huntington's disease. Medivation is committed to aggressively advancing development of Dimebon for patients and families devastated by Huntington's disease."

Full results from the Phase 2 study will be submitted for presentation at an upcoming scientific meeting.

About Huntington's Disease

Huntington's disease is a progressive, neurodegenerative disease that affects approximately 30,000 people in the U.S., with an additional 150,000 at risk, qualifying it as an orphan drug indication. It is caused by the death of specific brain cells and is characterized by the gradual development of involuntary muscle movement, progressive deterioration of cognitive processes and memory (dementia) and severe behavioral disturbances. There are currently no drugs approved by the U.S. Food and Drug Administration to treat this uniformly fatal genetic disorder.

About Dimebon

Dimebon is an orally-available small molecule that has been shown to inhibit brain cell death in preclinical models relevant to Alzheimer's disease and Huntington's disease, making it a potential treatment for these and other neurodegenerative diseases. The Company is currently enrolling patients in an international confirmatory Phase 3 clinical trial evaluating the efficacy and safety of Dimebon in patients with mild-to-moderate Alzheimer's disease. Preclinical data generated to date suggest that Dimebon operates through a novel mitochondrial mechanism of action.

Teleconference/Webcast Details

Medivation will host a teleconference at 5:00 p.m. Eastern Daylight Time today. To participate in the live call by telephone, please dial 877-419-6590 from the U.S. or 719-3
'/>"/>

SOURCE Medivation, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Medivations MDV3100 Demonstrates Substantial PSA Reductions in First Patient Groups Treated in Phase 1-2 Hormone Refractory Prostate Cancer Trial
2. Medivations Dimebon(TM) Stabilizes Behavioral Symptoms in Alzheimers Disease Patients, Resulting in Reduced Caregiver Distress
3. Medivations Dimebon(TM) Significantly Improved Daily Function in Alzheimers Disease Patients, Resulting in Reduced Need for Caregiver Assistance
4. Medivations Dimebon(TM) Significantly Improved Thinking and Memory in Alzheimers Disease Patients Over One Year
5. Medivation Announces Presentation of MDV3100 Clinical Data in Patients With Castration-Resistant Prostate Cancer at 44th American Society of Clinical Oncology Annual Meeting
6. Medivation Announces Presentation of Positive MDV3100 Clinical Data in Castration-Resistant Prostate Cancer Patients at 44th ASCO Annual Meeting
7. Medivation Initiates Second Pivotal Phase 3 Trial of Dimebon(TM) in Patients With Alzheimers Disease
8. Medivation to Host Conference Call at 5 p.m. EDT Monday to Discuss Top-Line Phase 2 Study Results in Huntingtons Disease
9. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
10. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
11. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... India , July 11, 2014  Major ... treatment of cancer are being highlighted in a ... Mumbai from 10-12 July, 2014.  Renowned national ... to share best practices and exchange knowledge on ... precise, accurate and efficient. The ...
(Date:7/10/2014)... , July 10, 2014  Breg, Inc., a ... has launched the FreeRunner™ knee brace with new ... from patella mal-tracking return to active lifestyles.  FreeRunner,s ... other braces, providing support when patients need it ... they don,t. Patellofemoral issues are the ...
(Date:7/10/2014)... 2014 Yesterday, former Congressman Patrick ... manufacturing facility. Rep. Kennedy and Dick Moberg ... cutting-edge research in neurological disease and treatment. ... advocate, Garen Staglin , created One Mind, ... changes that will radically accelerate the development and ...
Breaking Medicine Technology:Improving quality and access to advanced cancer care in India and South Asia 2Improving quality and access to advanced cancer care in India and South Asia 3Improving quality and access to advanced cancer care in India and South Asia 4Improving quality and access to advanced cancer care in India and South Asia 5Breg Introduces Knee Brace to Help Runners with Patellofemoral Pain Syndrome 2Representative Patrick Kennedy visits Moberg's medical device facility to discuss improvement in brain injury care 2
... 22 Mylan Inc. (Nasdaq: MYL ) announced today that it ... 2010 , at 10 a.m. ET , to review the company,s financial ... Mylan will release its financial results on April 29 before the ... The dial-in number to ...
... April 22 Ampio Pharmaceuticals, Inc. (OTC Bulletin Board: AMPE), today ... acquire DMI Biosciences, Inc. , , ... This acquisition will give AMPIO access to all rights, royalties and patents ... a specialty pharmaceutical company after demonstrating safety and efficacy in a Phase ...
Cached Medicine Technology:Mylan Schedules First Quarter 2010 Financial Results Conference Call and Live Webcast 2Ampio Pharmaceuticals to Acquire DMI Biosciences, Inc. 2Ampio Pharmaceuticals to Acquire DMI Biosciences, Inc. 3
(Date:7/14/2014)... that promote mental activity, and moderate physical activity ... development of Alzheimer,s disease and dementia in later ... the Alzheimer,s Association International Conference 2014 (AAIC 2014) ... 2014 also showed that sleep problems especially ... may increase dementia risk in veterans. Additionally, in ...
(Date:7/14/2014)... (PRWEB) July 14, 2014 Spine ... in complete spine care—from diagnosis to treatment and recovery. ... are either certified in or training for certification in ... Adame, have recently completed the extensive program. , “We ... The McKenzie Method results in better outcomes for spine ...
(Date:7/14/2014)... 2014 Cadeon Associates Inc. ... into Money,” today announced that it has joined ... that helps partners resell, deploy, and develop solutions ... platform. TIBCO Software Inc. is a global leader ... Spotfire analytics, providing businesses the ability to capture ...
(Date:7/13/2014)... 2014 Recently, TopDresses100.com, a popular dress ... range of multi-colored Quinceanera dresses to its ... of these colorful outfits are guaranteed to be quality ... to 68% off. , TopDresses100.com has a wide variety ... all its items are in stock and ready to ...
(Date:7/13/2014)... July 14, 2014 Worldwide ladies are ... selection. Angeldress.co.uk has taken a different approach and has ... items are offered in more colour choices that responded ... famous brand of women’s special occasion apparels. The company’s ... dress specialists are working hard to create the best ...
Breaking Medicine News(10 mins):Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 2Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 3Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 4Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 5Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 6Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 2Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 3Health News:Cadeon Associates Inc. Joins TIBCO Spotfire Partner Network 2Health News:Cadeon Associates Inc. Joins TIBCO Spotfire Partner Network 3Health News:Cheap Multi-colored Quinceanera Dresses From TopDresses100.com 2Health News:Angeldress.co.uk Announces Summer Sale For Pink And Red Bridesmaid Dresses; The Current Discount Is Up To 80% Off 2
... said that Asians including Indians are being hit the most ... done by doctors that fails to// detect these problems. ... measure of weight divided by height- is used in the ... East and South Asians were affected by weight-related ill health ...
... hang heavy with heart problems, going back at least two ... she hit age 50,// Catherine got nervous. ,A ... and perhaps those of others in her family tree. She ... causes her heart muscle to grow too thick. The extra ...
... healers in Ghana claim to have developed a product ... system in much the same way as Anti-Retroviral Therapy ... ,Ghana Aids Commission (GAC), Catholic Relief Services (CRS) ... this project. Dr Anthony Normeshie, Executive Director, Health For ...
... pounds) is to have a fat removal surgery in Italy. ... world.// The Mexican is no longer able to move around ... , "We will hold a meeting in the coming days ... prepare the operating theater and the appropriate surgical tools," Head ...
... U.S.. 18 million people of the 28 million suffering from ... of these women get themselves treated, in spite of the ... ,Mayo Clinic in Arizona Women's Health Internal Medicine physicians ... last 5 years in order to understand this matter better. ...
... that although the heart treatment from Canadian biotech firm Vasogen ... still helped more than 70 per cent of patients.// ... was confident the detailed analysis presented at the World Congress ... promising commercial future. ,According to Celacade if all ...
Cached Medicine News:Health News:Fight Back Against Inherited Sudden-Death Heart Condition 2Health News:Fight Back Against Inherited Sudden-Death Heart Condition 3Health News:Fight Back Against Inherited Sudden-Death Heart Condition 4Health News:Migraine in women 2Health News:Migraine in women 3Health News:Heart Treatment from Vasogen Shows Promise 2
... GE's surgical navigation for ... system to integrate C-arm ... technology. It features automatic ... image to the patient's ...
... 20 years of CT engineering innovation and ... the forefront of the revolution in CT ... data at high speed with superb spatial ... extensive clinical experience and close cooperation with ...
... a family of multislice CT scanners. In ... also is available in an affordable Dual ... friendly user interface, advanced applications and high ... and Quad systems can be upgraded to ...
... 10 offers premium-level performance with a range of ... systems in the 8- and 10-slice market. ... time, and submillimeter isotropic imaging set it apart ... simple upgrade to a 16-slice system make the ...
Medicine Products: